Research Group: Non-coding Transcription

Our lab is interested in the functional consequences of non-coding transcription independent of the lncRNA. We study how the mechanism of transcription of non-coding regions affects nearby gene expression through changes in chromatin packaging and modification. We are pursuing how this dynamic non-coding transcription may be part of plant environmental sensing mechanisms by studying transcription kinetics in environmental interactions.

Only a small proportion of DNA in higher organisms represents genes. Interestingly, most non-coding sequences are actively transcribed to yield long non-coding RNA (lncRNA). Gene promoters represent a conserved source of lncRNA through divergent non-coding transcription. However, the generated lncRNA molecules are not usually conserved, whereas genome-wide non-coding transcription is found in wide range of organisms.






























Group members

Navn Titel Telefon E-mail
Giorgio Gullotta Ph.d.-stipendiat +4535327444 E-mail
Karina Chalenko Ph.d.-stipendiat +4535331992 E-mail
Katerina Adamusová Postdoc +4535335655 E-mail
María Luz Annacondia López Postdoc +4535331082 E-mail

Contact research group leader

Sebastian Marquardt
Associate Professor
Ph: +45 35 33 13 05