Mohammed Saddik Motawie

Mohammed Saddik Motawie

Associate Professor


  1. Published

    In vitro biochemical characterization of all barley endosperm starch synthases

    Cuesta-Seijo, J. A., Nielsen, M. M., Ruzanski, C., Krucewicz, K., Beeren, S. R., Rydhal, M. G., Yoshimura, Y., Striebeck, A., Motawie, Mohammed Saddik, Willats, W. G. T. & Palcic, M. M., 2016, In: Frontiers in Plant Science. 6, 17 p., 1265.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published
  3. Published

    Lotus japonicus flowers are defended by a cyanogenic β-glucosidase with highly restricted expression to essential reproductive organs

    Lai, D., Picmanova, M., Hachem, M. A., Motawie, Mohammed Saddik, Olsen, C. E., Møller, Birger Lindberg, Rook, F. & Takos, A. M., 2015, In: Plant Molecular Biology. 89, 1-2, p. 21-34 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    A General Method Based on the Use of N-Bromosuccinimide for Removal of the Thiophenyl Group at the Anomeric Position to Generate A Reducing Sugar with the Original Protecting Groups Still Present

    Motawie, Mohammed Saddik, Marcussen, J. & Møller, Birger Lindberg, 1995, In: Journal of Carbohydrate Chemistry. 14, 9, p. 1279-1294 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    A combined nuclear magnetic resonance and molecular dynamics study of the two structural motifs for mixed-linkage ß-glucans: methyl ß-cellobioside and methyl ß-laminarabioside

    Christensen, Niels Johan, Hansen, P. I., Larsen, F. H., Folkerman, T., Motawie, Mohammed Saddik & Engelsen, Søren Balling, 2010, In: Carbohydrate Research. 345, 4, p. 474-486 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    A facile protocol for direct conversion of unprotected sugars into phenyl 4,6,-O-acetylated-1,2-trans-thioglycosides

    Larsen, K., Olsen, C. E. & Motawie, Mohammed Saddik, 2003, In: Carbohydrate Research. 338, p. 199-202 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    A facile protocol fordirect conversion of unprotected sugars into phenyl 4,6-O-benzylidene-per-O-acetylated-1,2-trans-thioglycosides

    Larsen, K., Olsen, C. E. & Motawie, Mohammed Saddik, 2003, In: Carbohydrate Research. 338, p. 199-202 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    A flavin-dependent monooxygenase catalyzes the initial step in cyanogenic glycoside synthesis in ferns

    Thodberg, S., Sørensen, Mette, Bellucci, M., Crocoll, C., Bendtsen, Amalie Kofoed, Nelson, D. R., Motawie, Mohammed Saddik, Møller, Birger Lindberg & Neilson, Elizabeth Heather Jakobsen, 2020, In: Communications Biology . 3, 11 p., 507.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published
  10. Published

    A hydration study of (1->4) and (1->6) linked a-glucans by comparative 10 ns molecular dynamics simulations and 500-MHz NMR

    Corzana, F., Motawie, Mohammed Saddik, Du Penhoat, C. H., Perez, S., Tschampel, S. M., Woods, R. J. & Engelsen, Søren Balling, 2004, In: Journal of Chemistry. 25, 4, p. 573-586 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    A novel route to synthesis of 6'''-a-maltotriosyl-maltohexaose and its use as substrate for starch synthase

    Damager, I., Olsen, C. E., Møller, Birger Lindberg & Motawie, Mohammed Saddik, 2002.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  12. Published

    A recycling pathway for cyanogenic glycosides evidenced by the comparative metabolic profiling in three cyanogenic plant species

    Picmanova, M., Neilson, Elizabeth Heather Jakobsen, Motawie, Mohammed Saddik, Olsen, C. E., Agerbirk, Niels, Gray, C. J., Flitsch, S., Meier, S., Silvestro, D., Jørgensen, Kirsten, Sánchez Pérez, R., Møller, Birger Lindberg & Bjarnholt, Nanna, 2015, In: Biochemical Journal. 469, 3, p. 375-389 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    A toolkit for engineering multi-enzyme pathways into higher plants

    Geu-Flores, Fernando, Nielsen, M. T., Motawie, Mohammed Saddik, Olsen, C. E. & Halkier, Barbara Ann, 2009.

    Research output: Contribution to conferencePosterResearch

  14. Published

    A toolkit for engineering multi-enzyme pathways into higher plants

    Geu-Flores, Fernando, Nielsen, M. T., Møldrup, M. E., Olsen, C. E., Motawie, Mohammed Saddik & Halkier, Barbara Ann, 2009. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  15. Published

    A ¤short route to malto-trisaccharide synthons: synthesis of the branched nonasaccharide, 6'''-alfa-maltotriosyl-maltohexaose

    Damager, I., Olsen, C. E., Møller, Birger Lindberg & Motawie, Mohammed Saddik, 2002, In: Synthesis. 3, p. 418-426 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Acid-catalysed rearrangement of glycosyl trichloroacetimidates: a novel route to glycosylamines

    Larsen, K., Olsen, C. E. & Motawie, Mohammed Saddik, 2008, In: Carbohydrate Research. 343, 2, p. 383-387 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    An Optimized Screen Reduces the Number of GA Transporters and Provides Insights Into Nitrate Transporter 1/Peptide Transporter Family Substrate Determinants

    Wulff, N., Ernst, H. A., Jørgensen, M. E., Lambertz, S., Maierhofer, T., Belew, Zeinu Mussa, Crocoll, C., Motawie, Mohammed Saddik, Geiger, D., Jørgensen, Flemming Steen, Mirza, Osman Asghar & Nour-Eldin, Hussam Hassan, 3 Oct 2019, In: Frontiers in Plant Science. 10, 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    An independent evolutionary origin for insect deterrent cucurbitacins in Iberis amara

    Dong, L., Almeida Robles, A. R., Pollier, J., Khakimov, Bekzod, Bassard, J. A., Miettinen, K., Stærk, Dan, Mehran, R., Olsen, C. E., Motawie, Mohammed Saddik, Goossens, A. & Bak, Søren, 2021, In: Molecular Biology and Evolution. 38, 11, p. 4659-4673 15 p., msab213.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Arabidopsis thaliana RGXT1 and RGXT2 encode Golgi-localized (1,3)-alpha-D-xylosyltransferases involved in the synthesis of pectic rhamnogalacturonan-II

    Madsen, J. E., Petersen, Bent L, Motawie, Mohammed Saddik, Damager, I., Faik, A., Olsen, C. E., Ishii, T., Clausen, Henrik, Ulvskov, Peter & Geshi, N., 2006, In: Plant Cell. 18, 10, p. 2593-2607 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Biochemical analysis of a multifunctional cytochrome P450 (CYP51) enzyme required for synthesis of antimicrobial triterpenes in plants

    Geisler, K., Hughes, R. K., Sainsbury, F., Lomonossoff, G. P., Rejzek, M., Fairhurst, S., Olsen, C. E., Motawie, Mohammed Saddik, Melton, R. E., Hemmings, A. M., Bak, Søren & Osbourn, A., 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 35, p. E3360-E3367 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Biosynthesis and biotechnological production of the anti-obesity agent celastrol

    Zhao, Yong, Hansen, N. L., Duan, Yaotao, Prasad, M., Motawie, Mohammed Saddik, Møller, Birger Lindberg, Pateraki, Irini, Stærk, Dan, Bak, Søren, Miettinen, Karel & Kampranis, Sotirios, 2023, In: Nature Chemistry. 15, p. 1236–1246

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Biosynthesis of rhodiocyanosides in Lotus japonicus: Rhodiocyanoside A is synthesized from (Z)-2-methylbutanaloxime via 2-methyl-2-butenenitrile

    Saito, S., Motawie, Mohammed Saddik, Olsen, C. E., Møller, Birger Lindberg & Bak, Søren, 2012, In: Phytochemistry. 77, p. 260-267 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Biosynthesis of the cyanogenic glucosides linamarin and lotaustralin in cassava: isolation, biochemical, characterization, and expression pattern of CYP71E7, the oxime-metabolizing cytochrome P450 enzyme

    Jørgensen, Kirsten, Morant, A. V., Morant, M., Jensen, N. B., Olsen, C. E., Kannangara, R. M., Motawie, Mohammed Saddik, Møller, Birger Lindberg & Bak, Søren, 2011, In: Plant Physiology. 155, 1, p. 282-292 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Biosynthesis of the leucine derived α-, β- and γ-hydroxynitrile glucosides in barley (Hordeum vulgare L.)

    Knoch, E., Motawie, Mohammed Saddik, Olsen, C. E., Møller, Birger Lindberg & Lyngkjær, M. F., 2016, In: Plant Journal. 88, 2, p. 247-256 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Bottom-up elucidation of glycosidic bond stereochemistry

    Gray, C. J., Schindler, B., Migas, L. G., Picmanova, M., Allouche, A. R., Green, A. P., Mandal, S., Motawie, Mohammed Saddik, Sánchez Pérez, R., Bjarnholt, Nanna, Møller, Birger Lindberg, Rijs, A. M., Barran, P. E., Compagnon, I., Eyers, C. E. & Flitsch, S. L., 2017, In: Analytical Chemistry. 89, 8, p. 4540-4549 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Cell Wall Biosynthesis: Heterologous expression of Arabidopsis glycosyltransferases in Nicotiana benthamiana

    Scheller, H. V., Oikawa, A., Manabe, Y., Johansen, J., Höfte, H., Motawie, Mohammed Saddik & Geshi, N., 2008.

    Research output: Contribution to conferencePosterResearch

  27. Published

    Characterization and expression profile of two UDP-glucosyltransferases, UGT85K4 and UGT85K5, catalyzing the last step in cyanogenic glucoside biosynthesis in cassava

    Kannangara, R. M., Motawie, Mohammed Saddik, Hansen, N. K. K., Paquette, S. M., Olsen, C. E., Møller, Birger Lindberg & Jørgensen, Kirsten, 2011, In: Plant Journal. 68, 2, p. 287-301 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Characterization of a dynamic metabolon producing the defense compound dhurrin in sorghum

    Laursen, Tomas, Borch-Jensen, J., Baden, C. K., Bavishi, K., Torta, F., Martens, Helle Jakobe, Silvestro, D., Hatzakis, Nikos, Wenk, M. R., Dafforn, T. R., Olsen, C. E., Motawie, Mohammed Saddik, Hamberger, B. R., Møller, Birger Lindberg & Bassard, J. A., 2016, In: Science (New York, N.Y.). 354, 6314, p. 890-893 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Chemical Synthesis of L-Fucose Derivatives for Acceptor Specificity Characterisation of Plant Cell Wall Glycosyltransferases

    Damager, I., Olsen, C. E., Madsen, J. E., Jørgensen, Bodil, Petersen, Bent L, Ulvskov, Peter, Møller, Birger Lindberg & Motawie, Mohammed Saddik, 2017, In: ChemistrySelect. 2, 3, p. 997-1007 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Chemical Synthesis of linear malto-oligosaccharides

    Larsen, K., Olsen, C. E., Møller, Birger Lindberg & Motawie, Mohammed Saddik, 2000.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  31. Published

    Chemical synthesis and NMR spectra of a protected branched-tetrasaccharide thioglycoside, a useful intermediate for the synthesis of branched oligosaccharides

    Motawie, Mohammed Saddik, Olsen, C. E., Møller, Birger Lindberg & Marcussen, J., 15 Jan 1994, In: Carbohydrate Research. 252, p. 69-84 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Chemical synthesis of 6'''-alfa-maltotriosyl-maltohexaose as substrate for enzymes in starch biosynthesis and degradation

    Damager, I., Olsen, C. E., Møller, Birger Lindberg & Motawie, Mohammed Saddik, 1999, In: Carbohydrate Research. 320, p. 19-30 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Chemical synthesis of 6´-α-maltosyl-maltotriose, a branched oligosaccharide representing the branch point of starch

    Motawie, Mohammed Saddik, Olsen, C. E., Enevoldsen, K., Marcussen, J. & Møller, Birger Lindberg, 7 Nov 1995, In: Carbohydrate Research. 277, 1, p. 109-123 15.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Chemical synthesis of 6´´´-aplha-maltotriosyl-maltohexaose as substrate for enzymes in starch biosynthesis and degradation

    Damager, I., Olsen, C. E., Møller, Birger Lindberg & Motawie, Mohammed Saddik, 2000.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  35. Published

    Chemical synthesis of a dual branched malto-decaose: a potential substrate for a-Amylases

    Damager, I., Jensen, M. T., Olsen, C. E., Blennow, Andreas, Møller, Birger Lindberg, Svensson, B. & Motawie, Mohammed Saddik, 2005, In: ChemBioChem. 6, 7, p. 1224-1233 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Chemical synthesis of defined linear and branched malto-oligosaccharides containing a-1-4 and a-1-6 linkages for use of starch biosynthesis and degradation

    Motawie, Mohammed Saddik, Damager, I., Larsen, K., Olsen, C. E. & Møller, Birger Lindberg, 2001.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  37. Published

    Chemical synthesis of defined oligosaccarides for plant biochemical studies

    Motawie, Mohammed Saddik, 2006. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  38. Published

    Chemical synthesis of linear malto-oligosaccharides

    Larsen, K., Olsen, C. E., Møller, Birger Lindberg & Motawie, Mohammed Saddik, 2001.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  39. Published

    Chemical synthesis of methyl 6'-a-maltosyl-a-maltotrioside and its use for investigation of the action of starch synthase II

    Damager, I., Olsen, C. E., Blennow, Andreas, Denyer, K., Møller, Birger Lindberg & Motawie, Mohammed Saddik, 2003, In: Carbohydrate Research. 338, p. 189-197 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Chemical synthesis of methyl 6'-alpha-maltotriosyl-alpha-maltotrioside and its use for investigation of the action of starch synthase II

    Damager, I., Olsen, C. E., Blennow, Andreas, Denyern, K., Møller, B. L. & Motawie, Mohammed Saddik, 2003, In: Carbohydrate Research. 338, p. 189-197 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Comparative study of small linear and branched alfa-glucans using size exclusion chromatography and static and dynamic light scattering

    Motawie, Mohammed Saddik, Damager, I., Olsen, C. E., Møller, Birger Lindberg, Engelsen, Søren Balling, Hansen, S. L., Øgendal, Lars Holm & Bauer, R., 2005, In: Biomacromolecules. 6, p. 143-151 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    DISAL glycosyl donors for the synthesis of a linear hexasaccharide under mild conditions

    Petersen, L., Laursen, J. B., Larsen, K., Motawie, Mohammed Saddik & Jensen, Knud Jørgen, 2003, In: Organic Letters. 5, 8, p. 1309-1312 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    De novo biosynthesis of vanillin in fission yeast (Schizosaccharomyces pombe) and baker's yeast (Saccharomyces cerevisiae)

    Hansen, E. H., Møller, Birger Lindberg, Kock, G. R., Bünner, C. M., Kristensen, C., Jensen, O. R., Okkels, F. T., Olsen, C. E., Motawie, Mohammed Saddik & Hansen, J., 2009, In: Applied and Environmental Microbiology. 75, 9, p. 2765-2774 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Defining optimal electron transfer partners for light-driven cytochrome P450 reactions

    Mellor, Silas Busck, Vinde, M. H., Nielsen, A. Z., Hanke, G. T., Abdiaziz, K., Roessler, M. M., Burow, Meike, Motawie, Mohammed Saddik, Møller, Birger Lindberg & Jensen, Poul Erik, 1 Sep 2019, In: Metabolic Engineering. 55, p. 33-43

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Degradation of lignin β-aryl ether units in Arabidopsis thaliana expressing LigD, LigF and LigG from Sphingomonas paucimobilis SYK-6

    Mnich, E., Vanholme, R., Oyarce, P., Liu, S., Lu, F., Goeminne, G., Jørgensen, Bodil, Motawie, Mohammed Saddik, Boerjan, W., Ralph, J., Ulvskov, Peter, Møller, Birger Lindberg, Bjarnholt, Nanna & Harholt, J., 2017, In: Plant Biotechnology Journal. 15, 5, p. 581-593 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Deletion of biosynthetic genes, specific SNP patterns and differences in transcript accumulation cause variation in hydroxynitrile glucoside content in barley cultivars

    Ehlert, M., Jagd, L. M., Braumann, I., Dockter, C., Crocoll, C., Motawie, Mohammed Saddik, Møller, Birger Lindberg & Lyngkjær, M. F., 5 Apr 2019, In: Scientific Reports. 9, p. 1-10 5730.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Development of novel monoclonal antibodies against starch and ulvan - implications for antibody production against polysaccharides with limited immunogenicity

    Rydahl, M. G., Kracun, S. K., Fangel, J. U., Michel, G., Guillouzo, A., Génicot, S., Mravec, Jozef, Harholt, J., Wilkens, C., Motawie, Mohammed Saddik, Svensson, B., Tranquet, O., Ralet, M., Jørgensen, Bodil, Domozych, D. S. & Willats, W. G. T., 2017, In: Scientific Reports. 7, 1, 13 p., 9326.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. E-pub ahead of print

    Disentangling hydroxynitrile glucoside biosynthesis in a barley (Hordeum vulgare) metabolon provides access to elite malting barleys for ethyl carbamate-free whisky production

    Jørgensen, M. E., Houston, K., Jørgensen, Hans Jørgen Lyngs, Thomsen, H. C., Tekaat, L., Krogh, C. T., Mellor, Silas Busck, Braune, K. B., Damm, M. L., Pedas, P. R., Voss, C., Rasmussen, M. W., Nielsen, K., Skadhauge, B., Motawie, Mohammed Saddik, Møller, Birger Lindberg, Dockter, C. & Sørensen, Mette, 23 Apr 2024, (E-pub ahead of print) In: Plant Journal.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    Dissipation of cyanogenic glucosides and cyanide in soil amended with white clover (Trifolium repens L.)

    Refsgaard, K., Bjarnholt, Nanna, Møller, Birger Lindberg, Motawie, Mohammed Saddik & Hansen, Hans Chr. Bruun, 2010, In: Soil Biology & Biochemistry. 42, 7, p. 1108-1113 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Diversification of an ancient theme: hydroxynitrile glucosides

    Bjarnholt, Nanna, Rook, F., Motawie, Mohammed Saddik, Cornett, Claus, Jørgensen, C., Olsen, C. E., Jaroszewski, J. W., Bak, Søren & Møller, Birger Lindberg, 2008, In: Phytochemistry. 69, 7, p. 1507-1516 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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