Copper release from copper intrauterine devices removed after up to 8 years of use

Research output: Contribution to journalJournal articleResearchpeer-review

Standard

Copper release from copper intrauterine devices removed after up to 8 years of use. / Kjær, Andreas; Laursen, Kjeld; Thormann, Lene; Borggaard, Ole; Lebech, Paul Erik.

In: Contraception, Vol. 47, No. 4, 04.1993, p. 349-358.

Research output: Contribution to journalJournal articleResearchpeer-review

Harvard

Kjær, A, Laursen, K, Thormann, L, Borggaard, O & Lebech, PE 1993, 'Copper release from copper intrauterine devices removed after up to 8 years of use', Contraception, vol. 47, no. 4, pp. 349-358. https://doi.org/10.1016/0010-7824(93)90032-3

APA

Kjær, A., Laursen, K., Thormann, L., Borggaard, O., & Lebech, P. E. (1993). Copper release from copper intrauterine devices removed after up to 8 years of use. Contraception, 47(4), 349-358. https://doi.org/10.1016/0010-7824(93)90032-3

Vancouver

Kjær A, Laursen K, Thormann L, Borggaard O, Lebech PE. Copper release from copper intrauterine devices removed after up to 8 years of use. Contraception. 1993 Apr;47(4):349-358. https://doi.org/10.1016/0010-7824(93)90032-3

Author

Kjær, Andreas ; Laursen, Kjeld ; Thormann, Lene ; Borggaard, Ole ; Lebech, Paul Erik. / Copper release from copper intrauterine devices removed after up to 8 years of use. In: Contraception. 1993 ; Vol. 47, No. 4. pp. 349-358.

Bibtex

@article{88b35584e7064e39a6c04f31a6cb9ea9,
title = "Copper release from copper intrauterine devices removed after up to 8 years of use",
abstract = "We studied the copper-releasing ability, weight and microscopic appearance of 2 copper-bearing intrauterine devices (IUDs), Copper-T Cu 200 (CuT) and Nova-T Cu 200 Ag (NovaT), after they had been in utero for up to 8 years. In addition, we studied whether IUDs removed from pregnant women showed different copper release. We found that IUD weight was a linear, negative function of duration of use, and that less than 20% of total copper would be released over a period of 8 years. The average copper-releasing ability was significantly higher for CuT than for NovaT (82.6 ± 6.4 vs. 42.7 ± 2.6 μg/day). The copper release was constant and thus unrelated to duration of use. Copper-releasing ability was similar in IUDs removed from pregnant and non-pregnant women. Fragmentation or minor defects only occurred in 3% of the IUDs and no correlation was found between deposits or corrosion and copper release rates. We conclude that CuT and NovaT both have constant copper release for at least 5-6 years and that the useful life-span probably can be prolonged to 6-8 years or more.",
author = "Andreas Kj{\ae}r and Kjeld Laursen and Lene Thormann and Ole Borggaard and Lebech, {Paul Erik}",
year = "1993",
month = apr,
doi = "10.1016/0010-7824(93)90032-3",
language = "English",
volume = "47",
pages = "349--358",
journal = "Contraception",
issn = "0010-7824",
publisher = "Elsevier",
number = "4",

}

RIS

TY - JOUR

T1 - Copper release from copper intrauterine devices removed after up to 8 years of use

AU - Kjær, Andreas

AU - Laursen, Kjeld

AU - Thormann, Lene

AU - Borggaard, Ole

AU - Lebech, Paul Erik

PY - 1993/4

Y1 - 1993/4

N2 - We studied the copper-releasing ability, weight and microscopic appearance of 2 copper-bearing intrauterine devices (IUDs), Copper-T Cu 200 (CuT) and Nova-T Cu 200 Ag (NovaT), after they had been in utero for up to 8 years. In addition, we studied whether IUDs removed from pregnant women showed different copper release. We found that IUD weight was a linear, negative function of duration of use, and that less than 20% of total copper would be released over a period of 8 years. The average copper-releasing ability was significantly higher for CuT than for NovaT (82.6 ± 6.4 vs. 42.7 ± 2.6 μg/day). The copper release was constant and thus unrelated to duration of use. Copper-releasing ability was similar in IUDs removed from pregnant and non-pregnant women. Fragmentation or minor defects only occurred in 3% of the IUDs and no correlation was found between deposits or corrosion and copper release rates. We conclude that CuT and NovaT both have constant copper release for at least 5-6 years and that the useful life-span probably can be prolonged to 6-8 years or more.

AB - We studied the copper-releasing ability, weight and microscopic appearance of 2 copper-bearing intrauterine devices (IUDs), Copper-T Cu 200 (CuT) and Nova-T Cu 200 Ag (NovaT), after they had been in utero for up to 8 years. In addition, we studied whether IUDs removed from pregnant women showed different copper release. We found that IUD weight was a linear, negative function of duration of use, and that less than 20% of total copper would be released over a period of 8 years. The average copper-releasing ability was significantly higher for CuT than for NovaT (82.6 ± 6.4 vs. 42.7 ± 2.6 μg/day). The copper release was constant and thus unrelated to duration of use. Copper-releasing ability was similar in IUDs removed from pregnant and non-pregnant women. Fragmentation or minor defects only occurred in 3% of the IUDs and no correlation was found between deposits or corrosion and copper release rates. We conclude that CuT and NovaT both have constant copper release for at least 5-6 years and that the useful life-span probably can be prolonged to 6-8 years or more.

UR - http://www.scopus.com/inward/record.url?scp=0027466743&partnerID=8YFLogxK

U2 - 10.1016/0010-7824(93)90032-3

DO - 10.1016/0010-7824(93)90032-3

M3 - Journal article

C2 - 8508664

AN - SCOPUS:0027466743

VL - 47

SP - 349

EP - 358

JO - Contraception

JF - Contraception

SN - 0010-7824

IS - 4

ER -

ID: 283516725