Cytosolic glutamine synthetase: a target for improvement of crop nitrogen use efficiency?

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Cytosolic glutamine synthetase : a target for improvement of crop nitrogen use efficiency? / Thomsen, Hanne Cecilie; Eriksson, Ulf Dennis; Møller, Inge Skrumsager; Schjørring, Jan Kofod.

In: Trends in Plant Science, Vol. 19, No. 10, 2014, p. 656-663.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Thomsen, HC, Eriksson, UD, Møller, IS & Schjørring, JK 2014, 'Cytosolic glutamine synthetase: a target for improvement of crop nitrogen use efficiency?', Trends in Plant Science, vol. 19, no. 10, pp. 656-663. https://doi.org/10.1016/j.tplants.2014.06.002

APA

Thomsen, H. C., Eriksson, U. D., Møller, I. S., & Schjørring, J. K. (2014). Cytosolic glutamine synthetase: a target for improvement of crop nitrogen use efficiency? Trends in Plant Science, 19(10), 656-663. https://doi.org/10.1016/j.tplants.2014.06.002

Vancouver

Thomsen HC, Eriksson UD, Møller IS, Schjørring JK. Cytosolic glutamine synthetase: a target for improvement of crop nitrogen use efficiency? Trends in Plant Science. 2014;19(10):656-663. https://doi.org/10.1016/j.tplants.2014.06.002

Author

Thomsen, Hanne Cecilie ; Eriksson, Ulf Dennis ; Møller, Inge Skrumsager ; Schjørring, Jan Kofod. / Cytosolic glutamine synthetase : a target for improvement of crop nitrogen use efficiency?. In: Trends in Plant Science. 2014 ; Vol. 19, No. 10. pp. 656-663.

Bibtex

@article{e29869ce5479444089379ce848589a61,
title = "Cytosolic glutamine synthetase: a target for improvement of crop nitrogen use efficiency?",
abstract = "Overexpression of the cytosolic enzyme glutamine synthetase 1 (GS1) has been investigated in numerous cases with the goal of improving crop nitrogen use efficiency. However, the outcome has generally been inconsistent. Here, we review possible reasons underlying the lack of success and conclude that GS1 activity may be downregulated via a chain of processes elicited by metabolic imbalances and environmental constraints. We suggest that a pivotal role of GS1 may be related to the maintenance of essential nitrogen (N) flows and internal N sensing during critical stages of plant development. A number of more refined overexpression strategies exploiting gene stacking combined with tissue and cell specific targeting to overcome metabolic bottlenecks are considered along with their potential in relation to new N management strategies.",
keywords = "Glutamine synthetase, Nitrogen, Nitrogen use efficiency (NUE), Overexpression, Regulation",
author = "Thomsen, {Hanne Cecilie} and Eriksson, {Ulf Dennis} and M{\o}ller, {Inge Skrumsager} and Schj{\o}rring, {Jan Kofod}",
year = "2014",
doi = "10.1016/j.tplants.2014.06.002",
language = "English",
volume = "19",
pages = "656--663",
journal = "Trends in Plant Science",
issn = "1360-1385",
publisher = "Elsevier Ltd. * Trends Journals",
number = "10",

}

RIS

TY - JOUR

T1 - Cytosolic glutamine synthetase

T2 - a target for improvement of crop nitrogen use efficiency?

AU - Thomsen, Hanne Cecilie

AU - Eriksson, Ulf Dennis

AU - Møller, Inge Skrumsager

AU - Schjørring, Jan Kofod

PY - 2014

Y1 - 2014

N2 - Overexpression of the cytosolic enzyme glutamine synthetase 1 (GS1) has been investigated in numerous cases with the goal of improving crop nitrogen use efficiency. However, the outcome has generally been inconsistent. Here, we review possible reasons underlying the lack of success and conclude that GS1 activity may be downregulated via a chain of processes elicited by metabolic imbalances and environmental constraints. We suggest that a pivotal role of GS1 may be related to the maintenance of essential nitrogen (N) flows and internal N sensing during critical stages of plant development. A number of more refined overexpression strategies exploiting gene stacking combined with tissue and cell specific targeting to overcome metabolic bottlenecks are considered along with their potential in relation to new N management strategies.

AB - Overexpression of the cytosolic enzyme glutamine synthetase 1 (GS1) has been investigated in numerous cases with the goal of improving crop nitrogen use efficiency. However, the outcome has generally been inconsistent. Here, we review possible reasons underlying the lack of success and conclude that GS1 activity may be downregulated via a chain of processes elicited by metabolic imbalances and environmental constraints. We suggest that a pivotal role of GS1 may be related to the maintenance of essential nitrogen (N) flows and internal N sensing during critical stages of plant development. A number of more refined overexpression strategies exploiting gene stacking combined with tissue and cell specific targeting to overcome metabolic bottlenecks are considered along with their potential in relation to new N management strategies.

KW - Glutamine synthetase

KW - Nitrogen

KW - Nitrogen use efficiency (NUE)

KW - Overexpression

KW - Regulation

U2 - 10.1016/j.tplants.2014.06.002

DO - 10.1016/j.tplants.2014.06.002

M3 - Journal article

C2 - 25017701

AN - SCOPUS:84908174442

VL - 19

SP - 656

EP - 663

JO - Trends in Plant Science

JF - Trends in Plant Science

SN - 1360-1385

IS - 10

ER -

ID: 130099043