Selection in plant breeding has traditionally relied on scoring the phenotype. Marker assisted selection using DNA markers has proven to be useful for direct selection of some individual traits. Dramatic reduction in the price of nucleotide sequencing has led to description of a growing number of crop plants by their whole genome sequence. This, combined with affordable genotyping of individuals, has led to a dramatic increase in marker density for several crop plant species, allowing selection at genomic level to be practical, in the same way that has proven useful in animal breeding. The course focuses on genomic selection and prediction which is becoming possible in plant breeding.