Mohammed Saddik Motawie

Mohammed Saddik Motawie

Associate Professor


  1. 2024
  2. E-pub ahead of print

    Disentangling hydroxynitrile glucoside biosynthesis in a barley (Hordeum vulgare) metabolon provides access to elite malting barleys for ethyl carbamate-free whisky production

    Jørgensen, M. E., Houston, K., Jørgensen, Hans Jørgen Lyngs, Thomsen, H. C., Tekaat, L., Krogh, C. T., Mellor, Silas Busck, Braune, K. B., Damm, M. L., Pedas, P. R., Voss, C., Rasmussen, M. W., Nielsen, K., Skadhauge, B., Motawie, Mohammed Saddik, Møller, Birger Lindberg, Dockter, C. & Sørensen, Mette, 23 Apr 2024, (E-pub ahead of print) In: Plant Journal.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2023
  4. Published

    Biosynthesis and biotechnological production of the anti-obesity agent celastrol

    Zhao, Yong, Hansen, N. L., Duan, Yaotao, Prasad, M., Motawie, Mohammed Saddik, Møller, Birger Lindberg, Pateraki, Irini, Stærk, Dan, Bak, Søren, Miettinen, Karel & Kampranis, Sotirios, 2023, In: Nature Chemistry. 15, p. 1236–1246

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Systematic engineering pinpoints a versatile strategy for the expression of functional cytochrome P450 enzymes in Escherichia coli cell factories

    Poborsky, Michal, Crocoll, C., Motawie, Mohammed Saddik & Halkier, Barbara Ann, 2023, In: Microbial Cell Factories. 22, 10 p., 219.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    The causal mutation leading to sweetness in modern white lupin cultivars

    Mancinotti, Davide, Czepiel, K., Taylor, J. L., Galehshahi, H. G., Møller, L. A., Jensen, M. K., Motawie, Mohammed Saddik, Hufnagel, B., Soriano, A., Yeheyis, L., Kjaerulff, Louise, Péret, B., Stærk, Dan, Wendt, T., Nelson, M. N., Kroc, M. & Geu-Flores, Fernando, 2023, In: Science Advances. 9, 31, 10 p., eadg8866.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. 2022
  8. Published

    Structure-guided engineering of key amino acids in UGT85B1 controlling substrate and stereo-specificity in aromatic cyanogenic glucoside biosynthesis

    Del Giudice, R., Putkaradze, N., dos Santos, B. M., Hansen, Cecilie Ida Cetti, Crocoll, C., Motawie, Mohammed Saddik, Fredslund, F., Laursen, Tomas & Welner, D. H., 2022, In: Plant Journal. 111, 6, p. 1539-1549

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2021
  10. Published

    An independent evolutionary origin for insect deterrent cucurbitacins in Iberis amara

    Dong, L., Almeida Robles, A. R., Pollier, J., Khakimov, Bekzod, Bassard, J. A., Miettinen, K., Stærk, Dan, Mehran, R., Olsen, C. E., Motawie, Mohammed Saddik, Goossens, A. & Bak, Søren, 2021, In: Molecular Biology and Evolution. 38, 11, p. 4659-4673 15 p., msab213.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2020
  12. Published

    The dynamics of cyanide defences in the life cycle of an aposematic butterfly: Biosynthesis versus sequestration

    Pinheiro de Castro, É. C., Demirtas, R., Orteu, A., Olsen, C. E., Motawie, Mohammed Saddik, Zikan Cardoso, M., Zagrobelny, Mika & Bak, Søren, Jan 2020, In: Insect Biochemistry and Molecular Biology. 116, p. 1-9 103259.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    A flavin-dependent monooxygenase catalyzes the initial step in cyanogenic glycoside synthesis in ferns

    Thodberg, S., Sørensen, Mette, Bellucci, M., Crocoll, C., Bendtsen, Amalie Kofoed, Nelson, D. R., Motawie, Mohammed Saddik, Møller, Birger Lindberg & Neilson, Elizabeth Heather Jakobsen, 2020, In: Communications Biology . 3, 11 p., 507.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published
  15. Published

    Golgi-localized exo-β1,3-galactosidases involved in AGP modification and root cell expansion in Arabidopsis

    Nibbering, P., Petersen, Bent L, Motawie, Mohammed Saddik, Jørgensen, Bodil, Ulvskov, Peter & Niittylä, T., 2020, In: Journal of Biological Chemistry. 295, 31, p. 10851-10592

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Golgi-localized exo-β1,3-galactosidases involved in cell expansion and root rowth in Arabidopsis

    Nibbering, P., Petersen, Bent L, Motawie, Mohammed Saddik, Jørgensen, Bodil, Ulvskov, Peter & Niittylä, T., 2020, In: Journal of Biological Chemistry. 295, 31, p. 10581-10592

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Phenolic cross-links: building and de-constructing the plant cell wall

    Mnich, E., Bjarnholt, Nanna, Eudes, A., Harholt, J., Holland, C., Jørgensen, Bodil, Larsen, F. H., Liu, M., Manat, R., Meyer, A. S., Mikkelsen, J. D., Motawie, Mohammed Saddik, Muschiol, J., Møller, Birger Lindberg, Møller, S. R., Perzon, A., Petersen, Bent L, Ravn, J. L. & Ulvskov, Peter, 2020, In: Natural Product Reports. 37, 7, p. 919-961 43 p.

    Research output: Contribution to journalReviewResearchpeer-review

  18. Published

    Stabilization of dhurrin biosynthetic enzymes from Sorghum bicolor using a natural deep eutectic solvent

    Knudsen, C., Bavishi, K., Viborg, K. M., Drew, D. P., Simonsen, H. T., Motawie, Mohammed Saddik, Møller, Birger Lindberg & Laursen, Tomas, 2020, In: Phytochemistry. 170, 9 p., 112214.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Synthetic Biology of Cannabinoids and Cannabinoid Glucosides in Nicotiana benthamiana and Saccharomyces cerevisiae

    Gülck, T., Booth, J. K., Carvalho, Â., Khakimov, Bekzod, Crocoll, C., Motawie, Mohammed Saddik, Møller, Birger Lindberg, Bohlmann, J. & Gallage, N. J., 2020, In: Journal of Natural Products. 83, 10, p. 2877-2893 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. 2019
  21. Published

    An Optimized Screen Reduces the Number of GA Transporters and Provides Insights Into Nitrate Transporter 1/Peptide Transporter Family Substrate Determinants

    Wulff, N., Ernst, H. A., Jørgensen, M. E., Lambertz, S., Maierhofer, T., Belew, Zeinu Mussa, Crocoll, C., Motawie, Mohammed Saddik, Geiger, D., Jørgensen, Flemming Steen, Mirza, Osman Asghar & Nour-Eldin, Hussam Hassan, 3 Oct 2019, In: Frontiers in Plant Science. 10, 18 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Defining optimal electron transfer partners for light-driven cytochrome P450 reactions

    Mellor, Silas Busck, Vinde, M. H., Nielsen, A. Z., Hanke, G. T., Abdiaziz, K., Roessler, M. M., Burow, Meike, Motawie, Mohammed Saddik, Møller, Birger Lindberg & Jensen, Poul Erik, 1 Sep 2019, In: Metabolic Engineering. 55, p. 33-43

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Deletion of biosynthetic genes, specific SNP patterns and differences in transcript accumulation cause variation in hydroxynitrile glucoside content in barley cultivars

    Ehlert, M., Jagd, L. M., Braumann, I., Dockter, C., Crocoll, C., Motawie, Mohammed Saddik, Møller, Birger Lindberg & Lyngkjær, M. F., 5 Apr 2019, In: Scientific Reports. 9, p. 1-10 5730.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Sequestration and functional diversification of cyanogenic glucosides in the life cycle of Heliconius melpomene

    Castro, É. C. P. D., Demirtas, R., Orteu, A., Olsen, C. E., Motawie, Mohammed Saddik, Cardoso, M. Z., Zagrobelny, Mika & Bak, Søren, 2019, bioRxiv, 31 p.

    Research output: Working paperPreprintResearch

  25. 2018
  26. Published

    Glutathione transferases catalyze recycling of auto-toxic cyanogenic glucosides in sorghum

    Bjarnholt, Nanna, Neilson, Elizabeth Heather Jakobsen, Crocoll, C., Jørgensen, Kirsten, Motawie, Mohammed Saddik, Olsen, C. E., Dixon, D. P., Edwards, R. & Møller, Birger Lindberg, 2018, In: Plant Journal. 94, 6, p. 1109-1125

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Synthesis of 11-carbon terpenoids in yeast using protein and metabolic engineering

    Ignea, C., Pontini, M., Motawie, Mohammed Saddik, Maffei, M. E., Makris, A. M. & Kampranis, Sotirios, 2018, In: Nature Chemical Biology. 14, 12, p. 1090-1098 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Vitamin D-5 in Arabidopsis thaliana

    Silvestro, D., Villette, C., Delecolle, J., Olsen, C. E., Motawie, Mohammed Saddik, Geoffroy, P., Miesch, M., Jensen, Poul Erik, Heintz, D. & Schaller, H., 2018, In: Scientific Reports. 8, p. 1-8 16348.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. 2017
  30. Published

    Bottom-up elucidation of glycosidic bond stereochemistry

    Gray, C. J., Schindler, B., Migas, L. G., Picmanova, M., Allouche, A. R., Green, A. P., Mandal, S., Motawie, Mohammed Saddik, Sánchez Pérez, R., Bjarnholt, Nanna, Møller, Birger Lindberg, Rijs, A. M., Barran, P. E., Compagnon, I., Eyers, C. E. & Flitsch, S. L., 2017, In: Analytical Chemistry. 89, 8, p. 4540-4549 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Chemical Synthesis of L-Fucose Derivatives for Acceptor Specificity Characterisation of Plant Cell Wall Glycosyltransferases

    Damager, I., Olsen, C. E., Madsen, J. E., Jørgensen, Bodil, Petersen, Bent L, Ulvskov, Peter, Møller, Birger Lindberg & Motawie, Mohammed Saddik, 2017, In: ChemistrySelect. 2, 3, p. 997-1007 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Degradation of lignin β-aryl ether units in Arabidopsis thaliana expressing LigD, LigF and LigG from Sphingomonas paucimobilis SYK-6

    Mnich, E., Vanholme, R., Oyarce, P., Liu, S., Lu, F., Goeminne, G., Jørgensen, Bodil, Motawie, Mohammed Saddik, Boerjan, W., Ralph, J., Ulvskov, Peter, Møller, Birger Lindberg, Bjarnholt, Nanna & Harholt, J., 2017, In: Plant Biotechnology Journal. 15, 5, p. 581-593 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Development of novel monoclonal antibodies against starch and ulvan - implications for antibody production against polysaccharides with limited immunogenicity

    Rydahl, M. G., Kracun, S. K., Fangel, J. U., Michel, G., Guillouzo, A., Génicot, S., Mravec, Jozef, Harholt, J., Wilkens, C., Motawie, Mohammed Saddik, Svensson, B., Tranquet, O., Ralet, M., Jørgensen, Bodil, Domozych, D. S. & Willats, W. G. T., 2017, In: Scientific Reports. 7, 1, 13 p., 9326.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Origin and evolution of transporter substrate specificity within the NPF family: [with Correction]

    Jørgensen, M. E., Xu, Deyang, Crocoll, C., Ernst, H. A., Ramírez, D., Motawie, Mohammed Saddik, Olsen, C. E., Mirza, Osman Asghar, Nour-Eldin, Hussam Hassan & Halkier, Barbara Ann, 2017, In: eLife. 6, 30 p., e19466.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    The CYP79A1 catalyzed conversion of tyrosine to (E)-p-hydroxyphenylacetaldoxime unravelled using an improved method for homology modeling

    Vazquez Albacete, D., Montefiori, M., Kol, S., Motawie, Mohammed Saddik, Møller, Birger Lindberg, Olsen, L. & Nørholm, M. H. H., 2017, In: Phytochemistry. 135, p. 8-17 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Total biosynthesis of the cyclic AMP booster forskolin from Coleus forskohlii

    Pateraki, Irini, Andersen-Ranberg, Johan, Jensen, N. B., Wubshet, S. G., Heskes, A. M., Forman, Victor, Hallström, B., Hamberger, B., Motawie, Mohammed Saddik, Olsen, C. E., Stærk, Dan, Hansen, J., Møller, Birger Lindberg & Hamberger, B. R., 2017, In: eLife. 6, 28 p., e23001.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Transcript profiling of a bitter variety of narrow-leafed lupin to discover alkaloid biosynthetic genes

    Yang, T., Nagy, I., Mancinotti, Davide, Otterbach, S. L., Andersen, T. B., Motawie, Mohammed Saddik, Asp, T. & Geu-Flores, Fernando, 2017, In: Journal of Experimental Botany. 68, 20, p. 5527-5537 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. 2016
  39. Published

    In vitro biochemical characterization of all barley endosperm starch synthases

    Cuesta-Seijo, J. A., Nielsen, M. M., Ruzanski, C., Krucewicz, K., Beeren, S. R., Rydhal, M. G., Yoshimura, Y., Striebeck, A., Motawie, Mohammed Saddik, Willats, W. G. T. & Palcic, M. M., 2016, In: Frontiers in Plant Science. 6, 17 p., 1265.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Biosynthesis of the leucine derived α-, β- and γ-hydroxynitrile glucosides in barley (Hordeum vulgare L.)

    Knoch, E., Motawie, Mohammed Saddik, Olsen, C. E., Møller, Birger Lindberg & Lyngkjær, M. F., 2016, In: Plant Journal. 88, 2, p. 247-256 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Characterization of a dynamic metabolon producing the defense compound dhurrin in sorghum

    Laursen, Tomas, Borch-Jensen, J., Baden, C. K., Bavishi, K., Torta, F., Martens, Helle Jakobe, Silvestro, D., Hatzakis, Nikos, Wenk, M. R., Dafforn, T. R., Olsen, C. E., Motawie, Mohammed Saddik, Hamberger, B. R., Møller, Birger Lindberg & Bassard, J. A., 2016, In: Science (New York, N.Y.). 354, 6314, p. 890-893 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Fusion of ferredoxin and cytochrome P450 enables direct light-driven biosynthesis

    Mellor, Silas Busck, Nielsen, A. J. Z., Burow, Meike, Motawie, Mohammed Saddik, Jakubauskas, D., Møller, Birger Lindberg & Jensen, Poul Erik, 2016, In: ACS chemical biology. 11, 7, p. 1862-1869 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    General and stereocontrolled approach to the chemical synthesis of naturally occurring cyanogenic glucosides

    Møller, Birger Lindberg, Olsen, C. E. & Motawie, Mohammed Saddik, 2016, In: Journal of Natural Products. 79, 4, p. 1198-1202 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    High throughput screening of starch structures using carbohydrate microarrays

    Tanackovic, V., Rydahl, M. G., Pedersen, H. L., Motawie, Mohammed Saddik, Shaik, S. S., Mikkelsen, M. D., Jensen, S. L., Fangel, J. U., Willats, W. G. T. & Blennow, Andreas, 2016, In: Scientific Reports. 6, 9 p., 30551.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    Metabolic engineering of light-driven cytochrome P450 dependent pathways into Synechocystis sp. PCC 6803

    Wlodarczyk, A. J., Gnanasekaran, Thiyagarajan, Nielsen, A. J. Z., Nokolunga, N., Mellor, Silas Busck, Manja, L., Frederik Bang Thøfner, J., Olsen, C. E., Motawie, Mohammed Saddik, Burow, Meike, Pribil, Mathias, Feussner, I., Møller, Birger Lindberg & Jensen, Poul Erik, 2016, In: Metabolic Engineering. 33, p. 1-11 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    The biosynthetic gene cluster for the cyanogenic glucoside dhurrin in Sorghum bicolor contains its co-expressed vacuolar MATE transporter

    Darbani Shirvanehdeh, B., Motawie, Mohammed Saddik, Olsen, C. E., Nour-Eldin, Hussam Hassan, Møller, Birger Lindberg & Rook, F., 2016, In: Scientific Reports. 6, 8 p., 37079.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Transfer of the cytochrome P450-dependent dhurrin pathway from Sorghum bicolor into Nicotiana tabacum chloroplasts for light-driven synthesis

    Gnanasekaran, Thiyagarajan, Karcher, D., Nielsen, A. J. Z., Martens, Helle Jakobe, Ruf, S., Kroop, X., Olsen, C. E., Motawie, Mohammed Saddik, Pribil, Mathias, Møller, Birger Lindberg, Bock, R. & Jensen, Poul Erik, 2016, In: Journal of Experimental Botany. 67, 8, p. 2495-2506 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. 2015
  49. Published

    Lotus japonicus flowers are defended by a cyanogenic β-glucosidase with highly restricted expression to essential reproductive organs

    Lai, D., Picmanova, M., Hachem, M. A., Motawie, Mohammed Saddik, Olsen, C. E., Møller, Birger Lindberg, Rook, F. & Takos, A. M., 2015, In: Plant Molecular Biology. 89, 1-2, p. 21-34 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    A recycling pathway for cyanogenic glycosides evidenced by the comparative metabolic profiling in three cyanogenic plant species

    Picmanova, M., Neilson, Elizabeth Heather Jakobsen, Motawie, Mohammed Saddik, Olsen, C. E., Agerbirk, Niels, Gray, C. J., Flitsch, S., Meier, S., Silvestro, D., Jørgensen, Kirsten, Sánchez Pérez, R., Møller, Birger Lindberg & Bjarnholt, Nanna, 2015, In: Biochemical Journal. 469, 3, p. 375-389 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Diversified glucosinolate metabolism: biosynthesis of hydrogen cyanide and of the hydroxynitrile glucoside alliarinoside in relation to sinigrin metabolism in Alliaria petiolata

    Frisch, T., Motawie, Mohammed Saddik, Olsen, C. E., Agerbirk, Niels, Møller, Birger Lindberg & Bjarnholt, Nanna, 2015, In: Frontiers in Plant Science. 6, 16 p., 926.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    NMR characterization of chemically synthesized branched alpha-dextrin model compounds

    Petersen, B. O., Motawie, Mohammed Saddik, Møller, Birger Lindberg, Hindsgaul, O. & Meier, S., 2015, In: Carbohydrate Research. 403, p. 149-156 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    The bifurcation of the cyanogenic glucoside and glucosinolate biosynthetic pathways

    Sørensen, Mette, Kannangara, R. M., Olsen, C. E., Blomstedt, C. K., Gleadow, R. M., Jørgensen, Kirsten, Bak, Søren, Motawie, Mohammed Saddik & Møller, Birger Lindberg, 2015, In: The Plant Journal. 84, 3, p. 558-573 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. 2014
  55. Published

    Glucosinolate-related glucosides in Alliaria petiolata: sources of variation in the plant and different metabolism in an adapted specialist herbivore, Pieris rapae

    Frisch, T., Agerbirk, Niels, Davis, S., Cipollini, D., Olsen, C. E., Motawie, Mohammed Saddik, Bjarnholt, Nanna & Møller, Birger Lindberg, 2014, In: Journal of Chemical Ecology. 40, 10, p. 1063-1079 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    Sequestration, tissue distribution and developmental transmission of cyanogenic glucosides in a specialist insect herbivore

    Zagrobelny, Mika, Olsen, C. E., Pentzold, S., Fürstenberg-Hägg, J., Jørgensen, Kirsten, Bak, Søren, Møller, Birger Lindberg & Motawie, Mohammed Saddik, 2014, In: Insect Biochemistry and Molecular Biology. 44, p. 44-53 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    Synthesis of the allelochemical alliarinoside present in garlic mustard (Alliaria petiolata), an invasive plant species in North America

    Olsen, C. E., Møller, Birger Lindberg & Motawie, Mohammed Saddik, 2014, In: Carbohydrate Research. 394, p. 13-16 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  58. Published

    Vanillin formation from ferulic acid in Vanilla planifolia is catalysed by a single enzyme

    Gallage, N. J., Hansen, E. H., Kannangara, R. M., Olsen, C. E., Motawie, Mohammed Saddik, Jørgensen, Kirsten, Holme, I., Hebelstrup, K., Grisoni, M. & Møller, Birger Lindberg, 2014, In: Nature Communications. 5, 6, 14 p., 4037.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. 2013
  60. Published

    Biochemical analysis of a multifunctional cytochrome P450 (CYP51) enzyme required for synthesis of antimicrobial triterpenes in plants

    Geisler, K., Hughes, R. K., Sainsbury, F., Lomonossoff, G. P., Rejzek, M., Fairhurst, S., Olsen, C. E., Motawie, Mohammed Saddik, Melton, R. E., Hemmings, A. M., Bak, Søren & Osbourn, A., 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 35, p. E3360-E3367 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. Published

    Male-to-female transfer of 5-hydroxytryptophan glucoside during mating in Zyagena filipendulae (Lepidoptera)

    Zagrobelny, Mika, Motawie, Mohammed Saddik, Olsen, C. E., Bak, Søren & Møller, Birger Lindberg, 2013, In: Insect Biochemistry and Molecular Biology. 43, 11, p. 1037-1044 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  62. Published

    The use of trimethylsilyl cyanide derivatization for robust and broad-spectrum high-throughput gas chromatography–mass spectrometry based metabolomics

    Khakimov, Bekzod, Motawie, Mohammed Saddik, Bak, Søren & Engelsen, Søren Balling, 2013, In: Analytical and Bioanalytical Chemistry. 405, 28, p. 9193-9205 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. 2012
  64. Published

    Biosynthesis of rhodiocyanosides in Lotus japonicus: Rhodiocyanoside A is synthesized from (Z)-2-methylbutanaloxime via 2-methyl-2-butenenitrile

    Saito, S., Motawie, Mohammed Saddik, Olsen, C. E., Møller, Birger Lindberg & Bak, Søren, 2012, In: Phytochemistry. 77, p. 260-267 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. 2011
  66. Published

    Biosynthesis of the cyanogenic glucosides linamarin and lotaustralin in cassava: isolation, biochemical, characterization, and expression pattern of CYP71E7, the oxime-metabolizing cytochrome P450 enzyme

    Jørgensen, Kirsten, Morant, A. V., Morant, M., Jensen, N. B., Olsen, C. E., Kannangara, R. M., Motawie, Mohammed Saddik, Møller, Birger Lindberg & Bak, Søren, 2011, In: Plant Physiology. 155, 1, p. 282-292 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  67. Published

    Characterization and expression profile of two UDP-glucosyltransferases, UGT85K4 and UGT85K5, catalyzing the last step in cyanogenic glucoside biosynthesis in cassava

    Kannangara, R. M., Motawie, Mohammed Saddik, Hansen, N. K. K., Paquette, S. M., Olsen, C. E., Møller, Birger Lindberg & Jørgensen, Kirsten, 2011, In: Plant Journal. 68, 2, p. 287-301 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Genomic clustering of cyanogenic glucoside biosythetic genes aids their identification in Lotus japonicus and suggests the repeated evolution of this chemical defence pathway

    Takos, A. M., Knudsen, C., Lai, D., Kannangara, R. M., Mikkelsen, L., Motawie, Mohammed Saddik, Olsen, C. E., Sato, S., Tabata, S., Jørgensen, Kirsten, Møller, Birger Lindberg & Rook, F., 2011, In: Plant Journal. 68, 2, p. 273-286 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. Published

    Phenylalanine derived cyanogenic diglucosides from Eucalyptus camphora and their abundances in relation to ontogeny and tissue type

    Neilson, Elizabeth Heather Jakobsen, Goodger, J. Q. D., Motawie, Mohammed Saddik, Bjarnholt, Nanna, Frisch, T., Olsen, C. E., Møller, Birger Lindberg & Woodrow, I. E., 2011, In: Phytochemistry. 72, 18, p. 2325-2334 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  70. Published

    Phosphate esters in amylopectin clusters of potato tuber starch

    Wikman, J., Larsen, F. H., Motawie, Mohammed Saddik, Blennow, Andreas & Bertoft, E., 2011, In: International Journal of Biological Macromolecules. 48, 4, p. 639-649 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. 2010
  72. Published

    A combined nuclear magnetic resonance and molecular dynamics study of the two structural motifs for mixed-linkage ß-glucans: methyl ß-cellobioside and methyl ß-laminarabioside

    Christensen, Niels Johan, Hansen, P. I., Larsen, F. H., Folkerman, T., Motawie, Mohammed Saddik & Engelsen, Søren Balling, 2010, In: Carbohydrate Research. 345, 4, p. 474-486 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. Published

    Dissipation of cyanogenic glucosides and cyanide in soil amended with white clover (Trifolium repens L.)

    Refsgaard, K., Bjarnholt, Nanna, Møller, Birger Lindberg, Motawie, Mohammed Saddik & Hansen, Hans Chr. Bruun, 2010, In: Soil Biology & Biochemistry. 42, 7, p. 1108-1113 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  74. Published

    First principles insight into the a-Glucan structures of starch: their synthesis, conformation, and hydration

    Damager, I., Engelsen, Søren Balling, Blennow, Andreas, Møller, Birger Lindberg & Motawie, Mohammed Saddik, 2010, In: Chemical Reviews. 110, 4, p. 2049-2080 31 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    First principles insight into the α-glucan structures of starch: their synthesis, conformation, and hydration

    Damager, I., Engelsen, Søren Balling, Blennow, Andreas, Møller, Birger Lindberg & Motawie, Mohammed Saddik, 2010, In: Chemical Reviews. 110, 4, p. 2049-2080 32 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Genetic screening identifies cyanogenesis-deficient mutants of Lotus japonicus and reveals enzymatic specificity in hydroxynitrile glucoside metabolism

    Takos, A. M., Lai, D., Mikkelsen, L., Abou Hachem, M., Shelton, D. A., Motawie, Mohammed Saddik, Olsen, C. E., Wang, T. L., Martin, C. R. & Rook, F., 2010, In: Plant Cell. 22, p. 1605-1619 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. 2009
  78. Published
  79. Published

    A toolkit for engineering multi-enzyme pathways into higher plants

    Geu-Flores, Fernando, Nielsen, M. T., Motawie, Mohammed Saddik, Olsen, C. E. & Halkier, Barbara Ann, 2009.

    Research output: Contribution to conferencePosterResearch

  80. Published

    A toolkit for engineering multi-enzyme pathways into higher plants

    Geu-Flores, Fernando, Nielsen, M. T., Møldrup, M. E., Olsen, C. E., Motawie, Mohammed Saddik & Halkier, Barbara Ann, 2009. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  81. Published

    De novo biosynthesis of vanillin in fission yeast (Schizosaccharomyces pombe) and baker's yeast (Saccharomyces cerevisiae)

    Hansen, E. H., Møller, Birger Lindberg, Kock, G. R., Bünner, C. M., Kristensen, C., Jensen, O. R., Okkels, F. T., Olsen, C. E., Motawie, Mohammed Saddik & Hansen, J., 2009, In: Applied and Environmental Microbiology. 75, 9, p. 2765-2774 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  82. Published

    Engineering benzylglucosinolate into tobacco

    Mikkelsen, M. D., Geu-Flores, Fernando, Nielsen, M. T., Nafisi, M., Møldrup, M. E., Olsen, C. E., Motawie, Mohammed Saddik & Halkier, Barbara Ann, 2009. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  83. Published

    Engineering of benzyl glucosinolate identifies a critical γ-glutamyl peptidase

    Geu-Flores, Fernando, Nielsen, M. T., Nafisi, M., Møldrup, M. E., Olsen, C. E., Motawie, Mohammed Saddik & Halkier, Barbara Ann, 2009. 1 p.

    Research output: Contribution to conferencePosterResearch

  84. Published

    Glucosinolate engineering identifies a missing biosynthetic enzyme

    Geu-Flores, Fernando, Nielsen, M. T., Nafisi, M., Møldrup, M. E., Motawie, Mohammed Saddik, Olsen, C. E. & Halkier, Barbara Ann, 2009. 1 p.

    Research output: Contribution to conferencePosterResearch

  85. Published

    Glucosinolate engineering identifies a ¿-glutamyl peptidase

    Geu-Flores, Fernando, Nielsen, M. T., Nafisi, M., Møldrup, M. E., Olsen, C. E., Motawie, Mohammed Saddik & Halkier, Barbara Ann, 2009, In: Nature Chemical Biology. 5, p. 575-577 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  86. Published

    Glycosyltransferases involved in the plant cell wall polysaccharides biosynthesis

    Geshi, N., Okawa, A., Yin, L., Motawie, Mohammed Saddik & Scheller, H. V., 2009.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  87. Published

    Glycosyltransferases involved in the plant cell wall polysaccharides biosynthesis

    Geshi, N., Oikawa, A., Yin, L., Motawie, Mohammed Saddik & Scheller, H. V., 2009.

    Research output: Contribution to conferencePosterResearch

  88. Published

    Glycosyltransfserases Involved in the Plant Cell Wall Polysaccharides Biosynthesis

    Geshi, N., Oikawa, A., Yin, L., Motawie, Mohammed Saddik & Scheller, H. V., 2009.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  89. Published

    Isolation and characterization of a cassava cyanohydrin glycosultransferase, MeUGT85.1

    Kannangara, R. M., Jørgensen, Kirsten, Sørensen, Charlotte Syvbæk Dahl, Motawie, Mohammed Saddik, Paquette, S. & Møller, Birger Lindberg, 2009. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  90. Published
  91. Published

    Localization of individual ß-Glycosidases in almond (Prunus dulcis) using a specific sugar reducing assay

    Sánchez Pérez, R., Jørgensen, Kirsten, Motawie, Mohammed Saddik, Jørgensen, B., Dicenta, F. & Møller, Birger Lindberg, 2009. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  92. Published

    Localization of individual ß-glycosidases in almond (Prunus dulcis) using a specific sugar reducing assay

    Sánchez-Pérez, R., Jørgensen, Kirsten, Motawie, Mohammed Saddik, Jørgensen, B., Dicenta, F. & Møller, Birger Lindberg, 2009. 1 p.

    Research output: Contribution to conferencePosterResearch

  93. Published

    Molecular interactions between barley and oat ß-Glucans and phenolic derivatives

    Simonsen, H. T., Nielsen, M. S., Christensen, Niels Johan, Christensen, U., la Cour, T. V., Motawie, Mohammed Saddik, Jespersen, Birthe P Møller, Engelsen, Søren Balling & Møller, Birger Lindberg, 2009, In: Journal of Agricultural and Food Chemistry. 57, 5, p. 2056-2064 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  94. Published

    Starch phosphorylation - maltosidic restrains upon 3´- and 6´-phosphorylation investigated by chemical synthesis, molecular dynamics and NMR spectroscopy

    Hansen, P. I., Spraul, M., Dvortsak, P., Larsen, F. H., Blennow, Andreas, Motawie, Mohammed Saddik & Engelsen, Søren Balling, 2009, In: Biopolymers. 91, 3, p. 179-193 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Tissue and cellular localization of individual ß-glycosidases using a substrate-specific sugar reducing assay

    Sánchez-Pérez, R., Jørgensen, Kirsten, Motawie, Mohammed Saddik, Dicenta, F. & Møller, Birger Lindberg, 2009, In: Plant Journal. 60, 5, p. 894-906 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  96. 2008
  97. Published

    Acid-catalysed rearrangement of glycosyl trichloroacetimidates: a novel route to glycosylamines

    Larsen, K., Olsen, C. E. & Motawie, Mohammed Saddik, 2008, In: Carbohydrate Research. 343, 2, p. 383-387 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  98. Published

    Cell Wall Biosynthesis: Heterologous expression of Arabidopsis glycosyltransferases in Nicotiana benthamiana

    Scheller, H. V., Oikawa, A., Manabe, Y., Johansen, J., Höfte, H., Motawie, Mohammed Saddik & Geshi, N., 2008.

    Research output: Contribution to conferencePosterResearch

  99. Published

    Diversification of an ancient theme: hydroxynitrile glucosides

    Bjarnholt, Nanna, Rook, F., Motawie, Mohammed Saddik, Cornett, Claus, Jørgensen, C., Olsen, C. E., Jaroszewski, J. W., Bak, Søren & Møller, Birger Lindberg, 2008, In: Phytochemistry. 69, 7, p. 1507-1516 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  100. Published

    Diversification of an ancient theme: hydroxynitrile glucosides

    Bjarnholt, Nanna, Rook, F., Motawie, Mohammed Saddik, Cornett, Claus, Olsen, C. E., Jaroszewski, J. W., Bak, Søren & Møller, Birger Lindberg, 2008.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  101. Published

    Structure and hydration of the amylopectin trisaccharide building blocks - synthesis, NMR, and molecular dynamics

    Hansen, P. I., Larsen, F. H., Motawie, Mohammed Saddik, Blennow, Andreas, Spraul, M. & Dvortsak, P., 2008, In: Biopolymers. 89, 12, p. 1179-1193 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  102. 2007
  103. Published

    The molecular hydration of starch

    Hansen, P. I., Larsen, F. H., Motawie, Mohammed Saddik, Blennow, Andreas & Engelsen, Søren Balling, 2007. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  104. Published

    The structure and hydration of alpha-glucan model compounds

    Hansen, P. I., Larsen, F. H., Motawie, Mohammed Saddik, Blennow, Andreas & Engelsen, Søren Balling, 2007. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  105. 2006
  106. Published

    Arabidopsis thaliana RGXT1 and RGXT2 encode Golgi-localized (1,3)-alpha-D-xylosyltransferases involved in the synthesis of pectic rhamnogalacturonan-II

    Madsen, J. E., Petersen, Bent L, Motawie, Mohammed Saddik, Damager, I., Faik, A., Olsen, C. E., Ishii, T., Clausen, Henrik, Ulvskov, Peter & Geshi, N., 2006, In: Plant Cell. 18, 10, p. 2593-2607 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  107. Published

    Chemical synthesis of defined oligosaccarides for plant biochemical studies

    Motawie, Mohammed Saddik, 2006. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  108. 2005
  109. Published

    Chemical synthesis of a dual branched malto-decaose: a potential substrate for a-Amylases

    Damager, I., Jensen, M. T., Olsen, C. E., Blennow, Andreas, Møller, Birger Lindberg, Svensson, B. & Motawie, Mohammed Saddik, 2005, In: ChemBioChem. 6, 7, p. 1224-1233 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  110. Published

    Comparative study of small linear and branched alfa-glucans using size exclusion chromatography and static and dynamic light scattering

    Motawie, Mohammed Saddik, Damager, I., Olsen, C. E., Møller, Birger Lindberg, Engelsen, Søren Balling, Hansen, S. L., Øgendal, Lars Holm & Bauer, R., 2005, In: Biomacromolecules. 6, p. 143-151 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  111. Published

    Hydration of the double helical segment of amylopectin

    Hansen, P. I., Blennow, Andreas, Motawie, Mohammed Saddik & Engelsen, Søren Balling, 2005, Abstracts. Eurocarb, p. 1 1 p.

    Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearch

  112. Published

    Making and breaking the starch granule - plants dealing with crystalline matter

    Blennow, Andreas, Baunsgaard, L., Mikkelsen, R., Motawie, Mohammed Saddik, Glaring, M. A., Houborg, K., Mogensen, H. & Christiansen, C., 2005, Plant Biotech Denmark. p. 1 1 p.

    Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearch

  113. 2004
  114. Published

    A hydration study of (1->4) and (1->6) linked a-glucans by comparative 10 ns molecular dynamics simulations and 500-MHz NMR

    Corzana, F., Motawie, Mohammed Saddik, Du Penhoat, C. H., Perez, S., Tschampel, S. M., Woods, R. J. & Engelsen, Søren Balling, 2004, In: Journal of Chemistry. 25, 4, p. 573-586 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  115. Published

    Hydration of the Amylopectin Branch Point. Evidence of Restricted Conformational Diversity of the a-(1-6) Linkage

    F. Corzana, Motawie, Mohammed Saddik, C. Herve du Penhoat, F. van den Berg & A. Blennow, A., 2004, In: Journal of the American Chemical Sociaty. 126, p. 13144-13155 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  116. Published

    Hydration of the amylopectin branch point: evidence of restricted conformational diversity of the a-(1-6) linkage

    Corzana, F., Motawie, Mohammed Saddik, Penhoat, C. H. D., van der Berg, Franciscus Winfried J, Blennow, Andreas, Perez, S. & Engelsen, Søren Balling, 2004, In: Journal of the American Chemical Society. 126, 40, p. 13144-13155 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  117. Published

    Identification and characterization of novel glycosyltransferases in Arabidopsis thaliana: Xylosyltransferases involved in the synthesis of rhamnogalacturonan II

    Egelund, J., Petersen, Bent L, Faik, A., Motawie, Mohammed Saddik, Olsen, C. E., Ishii, T., Clausen, H., Ulvskov, Peter & Geshi, N., 2004.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  118. Published

    The crystal structure of a defined starch granule assembly unit

    Houborg, K., Motawie, Mohammed Saddik & Blennow, Andreas, 2004.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  119. 2003
  120. Published

    A facile protocol for direct conversion of unprotected sugars into phenyl 4,6,-O-acetylated-1,2-trans-thioglycosides

    Larsen, K., Olsen, C. E. & Motawie, Mohammed Saddik, 2003, In: Carbohydrate Research. 338, p. 199-202 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  121. Published

    A facile protocol fordirect conversion of unprotected sugars into phenyl 4,6-O-benzylidene-per-O-acetylated-1,2-trans-thioglycosides

    Larsen, K., Olsen, C. E. & Motawie, Mohammed Saddik, 2003, In: Carbohydrate Research. 338, p. 199-202 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  122. Published

    Chemical synthesis of methyl 6'-a-maltosyl-a-maltotrioside and its use for investigation of the action of starch synthase II

    Damager, I., Olsen, C. E., Blennow, Andreas, Denyer, K., Møller, Birger Lindberg & Motawie, Mohammed Saddik, 2003, In: Carbohydrate Research. 338, p. 189-197 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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