Mohammed Saddik Motawie

Mohammed Saddik Motawie

Associate Professor


  1. Published
  2. Published

    Glutathione transferases catalyze recycling of auto-toxic cyanogenic glucosides in sorghum

    Bjarnholt, Nanna, Neilson, Elizabeth Heather Jakobsen, Crocoll, C., Jørgensen, Kirsten, Motawie, Mohammed Saddik, Olsen, C. E., Dixon, D. P., Edwards, R. & Møller, Birger Lindberg, 2018, In: Plant Journal. 94, 6, p. 1109-1125

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Diversification of an ancient theme: hydroxynitrile glucosides

    Bjarnholt, Nanna, Rook, F., Motawie, Mohammed Saddik, Cornett, Claus, Olsen, C. E., Jaroszewski, J. W., Bak, Søren & Møller, Birger Lindberg, 2008.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  4. Published

    Diversification of an ancient theme: hydroxynitrile glucosides

    Bjarnholt, Nanna, Rook, F., Motawie, Mohammed Saddik, Cornett, Claus, Jørgensen, C., Olsen, C. E., Jaroszewski, J. W., Bak, Søren & Møller, Birger Lindberg, 2008, In: Phytochemistry. 69, 7, p. 1507-1516 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Making and breaking the starch granule - plants dealing with crystalline matter

    Blennow, Andreas, Baunsgaard, L., Mikkelsen, R., Motawie, Mohammed Saddik, Glaring, M. A., Houborg, K., Mogensen, H. & Christiansen, C., 2005, Plant Biotech Denmark. p. 1 1 p.

    Research output: Chapter in Book/Report/Conference proceedingConference abstract in proceedingsResearch

  6. Published

    Sequestration and functional diversification of cyanogenic glucosides in the life cycle of Heliconius melpomene

    Castro, É. C. P. D., Demirtas, R., Orteu, A., Olsen, C. E., Motawie, Mohammed Saddik, Cardoso, M. Z., Zagrobelny, Mika & Bak, Søren, 2019, bioRxiv, 31 p.

    Research output: Working paperPreprintResearch

  7. Published

    A combined nuclear magnetic resonance and molecular dynamics study of the two structural motifs for mixed-linkage ß-glucans: methyl ß-cellobioside and methyl ß-laminarabioside

    Christensen, Niels Johan, Hansen, P. I., Larsen, F. H., Folkerman, T., Motawie, Mohammed Saddik & Engelsen, Søren Balling, 2010, In: Carbohydrate Research. 345, 4, p. 474-486 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    The bifurcation of the cyanogenic glucoside and glucosinolate biosynthetic pathways

    Sørensen, Mette, Kannangara, R. M., Olsen, C. E., Blomstedt, C. K., Gleadow, R. M., Jørgensen, Kirsten, Bak, Søren, Motawie, Mohammed Saddik & Møller, Birger Lindberg, 2015, In: The Plant Journal. 84, 3, p. 558-573 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Hydration of the amylopectin branch point: evidence of restricted conformational diversity of the a-(1-6) linkage

    Corzana, F., Motawie, Mohammed Saddik, Penhoat, C. H. D., van der Berg, Franciscus Winfried J, Blennow, Andreas, Perez, S. & Engelsen, Søren Balling, 2004, In: Journal of the American Chemical Society. 126, 40, p. 13144-13155 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    A hydration study of (1->4) and (1->6) linked a-glucans by comparative 10 ns molecular dynamics simulations and 500-MHz NMR

    Corzana, F., Motawie, Mohammed Saddik, Du Penhoat, C. H., Perez, S., Tschampel, S. M., Woods, R. J. & Engelsen, Søren Balling, 2004, In: Journal of Chemistry. 25, 4, p. 573-586 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    The hydration of the amylopectin branch point A combined molecular dynamics and NMR study

    Corzana, F., Motawie, Mohammed Saddik & Engelsen, Søren Balling, 2002.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  12. Published

    In vitro biochemical characterization of all barley endosperm starch synthases

    Cuesta-Seijo, J. A., Nielsen, M. M., Ruzanski, C., Krucewicz, K., Beeren, S. R., Rydhal, M. G., Yoshimura, Y., Striebeck, A., Motawie, Mohammed Saddik, Willats, W. G. T. & Palcic, M. M., 2016, In: Frontiers in Plant Science. 6, 17 p., 1265.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    The action of starch synthase II on 6III-alfa-maltotriosyl-maltohexaose comprising the branch point of amylopectin

    Damager, I., Denyer, K., Motawie, Mohammed Saddik, Møller, Birger Lindberg & Blennow, Andreas, 2001, In: FEBS Journal. 268, p. 4878-4884 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    A ¤short route to malto-trisaccharide synthons: synthesis of the branched nonasaccharide, 6'''-alfa-maltotriosyl-maltohexaose

    Damager, I., Olsen, C. E., Møller, Birger Lindberg & Motawie, Mohammed Saddik, 2002, In: Synthesis. 3, p. 418-426 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Chemical synthesis of methyl 6'-a-maltosyl-a-maltotrioside and its use for investigation of the action of starch synthase II

    Damager, I., Olsen, C. E., Blennow, Andreas, Denyer, K., Møller, Birger Lindberg & Motawie, Mohammed Saddik, 2003, In: Carbohydrate Research. 338, p. 189-197 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Chemical synthesis of 6'''-alfa-maltotriosyl-maltohexaose as substrate for enzymes in starch biosynthesis and degradation

    Damager, I., Olsen, C. E., Møller, Birger Lindberg & Motawie, Mohammed Saddik, 1999, In: Carbohydrate Research. 320, p. 19-30 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Chemical synthesis of methyl 6'-alpha-maltotriosyl-alpha-maltotrioside and its use for investigation of the action of starch synthase II

    Damager, I., Olsen, C. E., Blennow, Andreas, Denyern, K., Møller, B. L. & Motawie, Mohammed Saddik, 2003, In: Carbohydrate Research. 338, p. 189-197 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Chemical synthesis of 6´´´-aplha-maltotriosyl-maltohexaose as substrate for enzymes in starch biosynthesis and degradation

    Damager, I., Olsen, C. E., Møller, Birger Lindberg & Motawie, Mohammed Saddik, 2000.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  19. Published

    Chemical Synthesis of L-Fucose Derivatives for Acceptor Specificity Characterisation of Plant Cell Wall Glycosyltransferases

    Damager, I., Olsen, C. E., Madsen, J. E., Jørgensen, Bodil, Petersen, Bent L, Ulvskov, Peter, Møller, Birger Lindberg & Motawie, Mohammed Saddik, 2017, In: ChemistrySelect. 2, 3, p. 997-1007 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    First principles insight into the a-Glucan structures of starch: their synthesis, conformation, and hydration

    Damager, I., Engelsen, Søren Balling, Blennow, Andreas, Møller, Birger Lindberg & Motawie, Mohammed Saddik, 2010, In: Chemical Reviews. 110, 4, p. 2049-2080 31 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    A novel route to synthesis of 6'''-a-maltotriosyl-maltohexaose and its use as substrate for starch synthase

    Damager, I., Olsen, C. E., Møller, Birger Lindberg & Motawie, Mohammed Saddik, 2002.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  22. Published

    Chemical synthesis of a dual branched malto-decaose: a potential substrate for a-Amylases

    Damager, I., Jensen, M. T., Olsen, C. E., Blennow, Andreas, Møller, Birger Lindberg, Svensson, B. & Motawie, Mohammed Saddik, 2005, In: ChemBioChem. 6, 7, p. 1224-1233 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    First principles insight into the α-glucan structures of starch: their synthesis, conformation, and hydration

    Damager, I., Engelsen, Søren Balling, Blennow, Andreas, Møller, Birger Lindberg & Motawie, Mohammed Saddik, 2010, In: Chemical Reviews. 110, 4, p. 2049-2080 32 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    The biosynthetic gene cluster for the cyanogenic glucoside dhurrin in Sorghum bicolor contains its co-expressed vacuolar MATE transporter

    Darbani Shirvanehdeh, B., Motawie, Mohammed Saddik, Olsen, C. E., Nour-Eldin, Hussam Hassan, Møller, Birger Lindberg & Rook, F., 2016, In: Scientific Reports. 6, 8 p., 37079.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Structure-guided engineering of key amino acids in UGT85B1 controlling substrate and stereo-specificity in aromatic cyanogenic glucoside biosynthesis

    Del Giudice, R., Putkaradze, N., dos Santos, B. M., Hansen, Cecilie Ida Cetti, Crocoll, C., Motawie, Mohammed Saddik, Fredslund, F., Laursen, Tomas & Welner, D. H., 2022, In: Plant Journal. 111, 6, p. 1539-1549

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Granule-bound starch synthase I in isolated starch granules elongates malto-oligosaccharides processively

    Denyer, K., Waite, D., Motawie, Mohammed Saddik, Møller, Birger Lindberg & Smith, A. M., 1999, In: Biochemical Journal. 340, p. 183-191 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    An independent evolutionary origin for insect deterrent cucurbitacins in Iberis amara

    Dong, L., Almeida Robles, A. R., Pollier, J., Khakimov, Bekzod, Bassard, J. A., Miettinen, K., Stærk, Dan, Mehran, R., Olsen, C. E., Motawie, Mohammed Saddik, Goossens, A. & Bak, Søren, 2021, In: Molecular Biology and Evolution. 38, 11, p. 4659-4673 15 p., msab213.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Identification and characterization of novel glycosyltransferases in Arabidopsis thaliana: Xylosyltransferases involved in the synthesis of rhamnogalacturonan II

    Egelund, J., Petersen, Bent L, Faik, A., Motawie, Mohammed Saddik, Olsen, C. E., Ishii, T., Clausen, H., Ulvskov, Peter & Geshi, N., 2004.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  29. Published

    Deletion of biosynthetic genes, specific SNP patterns and differences in transcript accumulation cause variation in hydroxynitrile glucoside content in barley cultivars

    Ehlert, M., Jagd, L. M., Braumann, I., Dockter, C., Crocoll, C., Motawie, Mohammed Saddik, Møller, Birger Lindberg & Lyngkjær, M. F., 5 Apr 2019, In: Scientific Reports. 9, p. 1-10 5730.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published
  31. Published

    Hydration of the Amylopectin Branch Point. Evidence of Restricted Conformational Diversity of the a-(1-6) Linkage

    F. Corzana, Motawie, Mohammed Saddik, C. Herve du Penhoat, F. van den Berg & A. Blennow, A., 2004, In: Journal of the American Chemical Sociaty. 126, p. 13144-13155 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Glucosinolate-related glucosides in Alliaria petiolata: sources of variation in the plant and different metabolism in an adapted specialist herbivore, Pieris rapae

    Frisch, T., Agerbirk, Niels, Davis, S., Cipollini, D., Olsen, C. E., Motawie, Mohammed Saddik, Bjarnholt, Nanna & Møller, Birger Lindberg, 2014, In: Journal of Chemical Ecology. 40, 10, p. 1063-1079 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Diversified glucosinolate metabolism: biosynthesis of hydrogen cyanide and of the hydroxynitrile glucoside alliarinoside in relation to sinigrin metabolism in Alliaria petiolata

    Frisch, T., Motawie, Mohammed Saddik, Olsen, C. E., Agerbirk, Niels, Møller, Birger Lindberg & Bjarnholt, Nanna, 2015, In: Frontiers in Plant Science. 6, 16 p., 926.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published
  35. Published

    Vanillin formation from ferulic acid in Vanilla planifolia is catalysed by a single enzyme

    Gallage, N. J., Hansen, E. H., Kannangara, R. M., Olsen, C. E., Motawie, Mohammed Saddik, Jørgensen, Kirsten, Holme, I., Hebelstrup, K., Grisoni, M. & Møller, Birger Lindberg, 2014, In: Nature Communications. 5, 6, 14 p., 4037.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Biochemical analysis of a multifunctional cytochrome P450 (CYP51) enzyme required for synthesis of antimicrobial triterpenes in plants

    Geisler, K., Hughes, R. K., Sainsbury, F., Lomonossoff, G. P., Rejzek, M., Fairhurst, S., Olsen, C. E., Motawie, Mohammed Saddik, Melton, R. E., Hemmings, A. M., Bak, Søren & Osbourn, A., 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 35, p. E3360-E3367 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Glycosyltransfserases Involved in the Plant Cell Wall Polysaccharides Biosynthesis

    Geshi, N., Oikawa, A., Yin, L., Motawie, Mohammed Saddik & Scheller, H. V., 2009.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  38. Published

    Glycosyltransferases involved in the plant cell wall polysaccharides biosynthesis

    Geshi, N., Okawa, A., Yin, L., Motawie, Mohammed Saddik & Scheller, H. V., 2009.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  39. Published

    Glycosyltransferases involved in the plant cell wall polysaccharides biosynthesis

    Geshi, N., Oikawa, A., Yin, L., Motawie, Mohammed Saddik & Scheller, H. V., 2009.

    Research output: Contribution to conferencePosterResearch

  40. Published

    A toolkit for engineering multi-enzyme pathways into higher plants

    Geu-Flores, Fernando, Nielsen, M. T., Møldrup, M. E., Olsen, C. E., Motawie, Mohammed Saddik & Halkier, Barbara Ann, 2009. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  41. Published

    A toolkit for engineering multi-enzyme pathways into higher plants

    Geu-Flores, Fernando, Nielsen, M. T., Motawie, Mohammed Saddik, Olsen, C. E. & Halkier, Barbara Ann, 2009.

    Research output: Contribution to conferencePosterResearch

  42. Published

    Glucosinolate engineering identifies a ¿-glutamyl peptidase

    Geu-Flores, Fernando, Nielsen, M. T., Nafisi, M., Møldrup, M. E., Olsen, C. E., Motawie, Mohammed Saddik & Halkier, Barbara Ann, 2009, In: Nature Chemical Biology. 5, p. 575-577 3 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Engineering of benzyl glucosinolate identifies a critical γ-glutamyl peptidase

    Geu-Flores, Fernando, Nielsen, M. T., Nafisi, M., Møldrup, M. E., Olsen, C. E., Motawie, Mohammed Saddik & Halkier, Barbara Ann, 2009. 1 p.

    Research output: Contribution to conferencePosterResearch

  44. Published

    Glucosinolate engineering identifies a missing biosynthetic enzyme

    Geu-Flores, Fernando, Nielsen, M. T., Nafisi, M., Møldrup, M. E., Motawie, Mohammed Saddik, Olsen, C. E. & Halkier, Barbara Ann, 2009. 1 p.

    Research output: Contribution to conferencePosterResearch

  45. Published

    Transfer of the cytochrome P450-dependent dhurrin pathway from Sorghum bicolor into Nicotiana tabacum chloroplasts for light-driven synthesis

    Gnanasekaran, Thiyagarajan, Karcher, D., Nielsen, A. J. Z., Martens, Helle Jakobe, Ruf, S., Kroop, X., Olsen, C. E., Motawie, Mohammed Saddik, Pribil, Mathias, Møller, Birger Lindberg, Bock, R. & Jensen, Poul Erik, 2016, In: Journal of Experimental Botany. 67, 8, p. 2495-2506 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Bottom-up elucidation of glycosidic bond stereochemistry

    Gray, C. J., Schindler, B., Migas, L. G., Picmanova, M., Allouche, A. R., Green, A. P., Mandal, S., Motawie, Mohammed Saddik, Sánchez Pérez, R., Bjarnholt, Nanna, Møller, Birger Lindberg, Rijs, A. M., Barran, P. E., Compagnon, I., Eyers, C. E. & Flitsch, S. L., 2017, In: Analytical Chemistry. 89, 8, p. 4540-4549 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Synthetic Biology of Cannabinoids and Cannabinoid Glucosides in Nicotiana benthamiana and Saccharomyces cerevisiae

    Gülck, T., Booth, J. K., Carvalho, Â., Khakimov, Bekzod, Crocoll, C., Motawie, Mohammed Saddik, Møller, Birger Lindberg, Bohlmann, J. & Gallage, N. J., 2020, In: Journal of Natural Products. 83, 10, p. 2877-2893 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    De novo biosynthesis of vanillin in fission yeast (Schizosaccharomyces pombe) and baker's yeast (Saccharomyces cerevisiae)

    Hansen, E. H., Møller, Birger Lindberg, Kock, G. R., Bünner, C. M., Kristensen, C., Jensen, O. R., Okkels, F. T., Olsen, C. E., Motawie, Mohammed Saddik & Hansen, J., 2009, In: Applied and Environmental Microbiology. 75, 9, p. 2765-2774 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    The molecular hydration of starch

    Hansen, P. I., Larsen, F. H., Motawie, Mohammed Saddik, Blennow, Andreas & Engelsen, Søren Balling, 2007. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  50. Published

    Structure and hydration of the amylopectin trisaccharide building blocks - synthesis, NMR, and molecular dynamics

    Hansen, P. I., Larsen, F. H., Motawie, Mohammed Saddik, Blennow, Andreas, Spraul, M. & Dvortsak, P., 2008, In: Biopolymers. 89, 12, p. 1179-1193 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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