The invasive butterbur contaminates stream and seepage water in groundwater wells with toxic pyrrolizidine alkaloids

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

The invasive butterbur contaminates stream and seepage water in groundwater wells with toxic pyrrolizidine alkaloids. / Kisielius, Vaidotas; Hama, Jawameer R.; Skrbic, Natasa; Hansen, Hans Christian Bruun; Strobel, Bjarne W.; Rasmussen, Lars Holm.

In: Scientific Reports, Vol. 10, No. 1, 19784, 2020.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Kisielius, V, Hama, JR, Skrbic, N, Hansen, HCB, Strobel, BW & Rasmussen, LH 2020, 'The invasive butterbur contaminates stream and seepage water in groundwater wells with toxic pyrrolizidine alkaloids', Scientific Reports, vol. 10, no. 1, 19784. https://doi.org/10.1038/s41598-020-76586-1

APA

Kisielius, V., Hama, J. R., Skrbic, N., Hansen, H. C. B., Strobel, B. W., & Rasmussen, L. H. (2020). The invasive butterbur contaminates stream and seepage water in groundwater wells with toxic pyrrolizidine alkaloids. Scientific Reports, 10(1), [19784]. https://doi.org/10.1038/s41598-020-76586-1

Vancouver

Kisielius V, Hama JR, Skrbic N, Hansen HCB, Strobel BW, Rasmussen LH. The invasive butterbur contaminates stream and seepage water in groundwater wells with toxic pyrrolizidine alkaloids. Scientific Reports. 2020;10(1). 19784. https://doi.org/10.1038/s41598-020-76586-1

Author

Kisielius, Vaidotas ; Hama, Jawameer R. ; Skrbic, Natasa ; Hansen, Hans Christian Bruun ; Strobel, Bjarne W. ; Rasmussen, Lars Holm. / The invasive butterbur contaminates stream and seepage water in groundwater wells with toxic pyrrolizidine alkaloids. In: Scientific Reports. 2020 ; Vol. 10, No. 1.

Bibtex

@article{afc137faa58b462fbe98c41b8d6c9b5a,
title = "The invasive butterbur contaminates stream and seepage water in groundwater wells with toxic pyrrolizidine alkaloids",
abstract = "Pyrrolizidine alkaloids (PAs) are persistent mutagenic and carcinogenic compounds produced by many common plant species. Health authorities recommend minimising human exposure via food and medicinal products to ensure consumer health and safety. However, there is little awareness that PAs can contaminate water resources. Therefore, no regulations exist to limit PAs in drinking water. This study measured a PA base concentration of similar to 70 ng/L in stream water adjacent to an invasive PA-producing plant Petasites hybridus (Asteraceae). After intense rain the PA concentration increased tenfold. In addition, PAs measured up to 230 ng/L in seepage water from groundwater wells. The dominant PAs in both water types corresponded to the most abundant PAs in the plants (senkirkine, senecionine, senecionine N-oxide). The study presents the first discovery of persistent plant toxins in well water and their associated risks. In addition, it for the first time reports monocrotaline and monocrotaline N-oxide in Petasites sp.",
keywords = "PETASITES-HYBRIDUS, N-OXIDE, HONEY, PHYTOTOXINS, QUANTIFICATION, ISOPETASIN, PLANTS, FEED, FOOD",
author = "Vaidotas Kisielius and Hama, {Jawameer R.} and Natasa Skrbic and Hansen, {Hans Christian Bruun} and Strobel, {Bjarne W.} and Rasmussen, {Lars Holm}",
year = "2020",
doi = "10.1038/s41598-020-76586-1",
language = "English",
volume = "10",
journal = "Scientific Reports",
issn = "2045-2322",
publisher = "nature publishing group",
number = "1",

}

RIS

TY - JOUR

T1 - The invasive butterbur contaminates stream and seepage water in groundwater wells with toxic pyrrolizidine alkaloids

AU - Kisielius, Vaidotas

AU - Hama, Jawameer R.

AU - Skrbic, Natasa

AU - Hansen, Hans Christian Bruun

AU - Strobel, Bjarne W.

AU - Rasmussen, Lars Holm

PY - 2020

Y1 - 2020

N2 - Pyrrolizidine alkaloids (PAs) are persistent mutagenic and carcinogenic compounds produced by many common plant species. Health authorities recommend minimising human exposure via food and medicinal products to ensure consumer health and safety. However, there is little awareness that PAs can contaminate water resources. Therefore, no regulations exist to limit PAs in drinking water. This study measured a PA base concentration of similar to 70 ng/L in stream water adjacent to an invasive PA-producing plant Petasites hybridus (Asteraceae). After intense rain the PA concentration increased tenfold. In addition, PAs measured up to 230 ng/L in seepage water from groundwater wells. The dominant PAs in both water types corresponded to the most abundant PAs in the plants (senkirkine, senecionine, senecionine N-oxide). The study presents the first discovery of persistent plant toxins in well water and their associated risks. In addition, it for the first time reports monocrotaline and monocrotaline N-oxide in Petasites sp.

AB - Pyrrolizidine alkaloids (PAs) are persistent mutagenic and carcinogenic compounds produced by many common plant species. Health authorities recommend minimising human exposure via food and medicinal products to ensure consumer health and safety. However, there is little awareness that PAs can contaminate water resources. Therefore, no regulations exist to limit PAs in drinking water. This study measured a PA base concentration of similar to 70 ng/L in stream water adjacent to an invasive PA-producing plant Petasites hybridus (Asteraceae). After intense rain the PA concentration increased tenfold. In addition, PAs measured up to 230 ng/L in seepage water from groundwater wells. The dominant PAs in both water types corresponded to the most abundant PAs in the plants (senkirkine, senecionine, senecionine N-oxide). The study presents the first discovery of persistent plant toxins in well water and their associated risks. In addition, it for the first time reports monocrotaline and monocrotaline N-oxide in Petasites sp.

KW - PETASITES-HYBRIDUS

KW - N-OXIDE

KW - HONEY

KW - PHYTOTOXINS

KW - QUANTIFICATION

KW - ISOPETASIN

KW - PLANTS

KW - FEED

KW - FOOD

U2 - 10.1038/s41598-020-76586-1

DO - 10.1038/s41598-020-76586-1

M3 - Journal article

C2 - 33188248

VL - 10

JO - Scientific Reports

JF - Scientific Reports

SN - 2045-2322

IS - 1

M1 - 19784

ER -

ID: 253448836