Plant P4-ATPase lipid flippases: How are they regulated?

Research output: Contribution to journal › Review › Research › peer-review

Standard

Plant P4-ATPase lipid flippases : How are they regulated? / Villagrana, Richard; López-Marqués, Rosa Laura.

In: Biochimica et Biophysica Acta - Molecular Cell Research, Vol. 1871, No. 1, 119599, 2024.

Research output: Contribution to journal › Review › Research › peer-review

Harvard

Villagrana, R & López-Marqués, RL 2024, 'Plant P4-ATPase lipid flippases: How are they regulated?', Biochimica et Biophysica Acta - Molecular Cell Research, vol. 1871, no. 1, 119599. https://doi.org/10.1016/j.bbamcr.2023.119599

APA

Villagrana, R., & López-Marqués, R. L. (2024). Plant P4-ATPase lipid flippases: How are they regulated? Biochimica et Biophysica Acta - Molecular Cell Research, 1871(1), [119599]. https://doi.org/10.1016/j.bbamcr.2023.119599

Vancouver

Villagrana R, López-Marqués RL. Plant P4-ATPase lipid flippases: How are they regulated? Biochimica et Biophysica Acta - Molecular Cell Research. 2024;1871(1). 119599. https://doi.org/10.1016/j.bbamcr.2023.119599

Author

Villagrana, Richard ; López-Marqués, Rosa Laura. / Plant P4-ATPase lipid flippases : How are they regulated?. In: Biochimica et Biophysica Acta - Molecular Cell Research. 2024 ; Vol. 1871, No. 1.

Bibtex

@article{eedac6a5d429442b8d5f0745f2d23334,
title = "Plant P4-ATPase lipid flippases: How are they regulated?",
abstract = "P4 ATPases are active membrane transporters that translocate lipids towards the cytosolic side of the biological membranes in eukaryotic cells. Due to their essential cellular functions, P4 ATPase activity is expected to be tightly controlled, but fundamental aspects of the regulation of plant P4 ATPases remain unstudied. In this mini-review, our knowledge of the regulatory mechanisms of yeast and mammalian P4 ATPases will be summarized, and sequence comparison and structural modelling will be used as a basis to discuss the putative regulation of the corresponding plant lipid transporters.",
keywords = "Autoinhibition, Flippases, Kinase regulation, P4 ATPases, Structural modelling",
author = "Richard Villagrana and L{\'o}pez-Marqu{\'e}s, {Rosa Laura}",
note = "Funding Information: Work in the L{\'o}pez-Marqu{\'e}s lab is financed by the Novo Nordisk Foundation (Project number NNF19OC0056580/NovoCrops ), the Carlsberg Foundation (project number CF21-0389 ) and the Independent Research Fund Denmark | Nature and Universe (FNU, project number 1026-00024B ). Publisher Copyright: {\textcopyright} 2023 The Author(s)",
year = "2024",
doi = "10.1016/j.bbamcr.2023.119599",
language = "English",
volume = "1871",
journal = "B B A - Molecular Cell Research",
issn = "0167-4889",
publisher = "Elsevier",
number = "1",

}

RIS

TY - JOUR

T1 - Plant P4-ATPase lipid flippases

T2 - How are they regulated?

AU - Villagrana, Richard

AU - López-Marqués, Rosa Laura

N1 - Funding Information: Work in the López-Marqués lab is financed by the Novo Nordisk Foundation (Project number NNF19OC0056580/NovoCrops ), the Carlsberg Foundation (project number CF21-0389 ) and the Independent Research Fund Denmark | Nature and Universe (FNU, project number 1026-00024B ). Publisher Copyright: © 2023 The Author(s)

PY - 2024

Y1 - 2024

N2 - P4 ATPases are active membrane transporters that translocate lipids towards the cytosolic side of the biological membranes in eukaryotic cells. Due to their essential cellular functions, P4 ATPase activity is expected to be tightly controlled, but fundamental aspects of the regulation of plant P4 ATPases remain unstudied. In this mini-review, our knowledge of the regulatory mechanisms of yeast and mammalian P4 ATPases will be summarized, and sequence comparison and structural modelling will be used as a basis to discuss the putative regulation of the corresponding plant lipid transporters.

AB - P4 ATPases are active membrane transporters that translocate lipids towards the cytosolic side of the biological membranes in eukaryotic cells. Due to their essential cellular functions, P4 ATPase activity is expected to be tightly controlled, but fundamental aspects of the regulation of plant P4 ATPases remain unstudied. In this mini-review, our knowledge of the regulatory mechanisms of yeast and mammalian P4 ATPases will be summarized, and sequence comparison and structural modelling will be used as a basis to discuss the putative regulation of the corresponding plant lipid transporters.

KW - Autoinhibition

KW - Flippases

KW - Kinase regulation

KW - P4 ATPases

KW - Structural modelling

U2 - 10.1016/j.bbamcr.2023.119599

DO - 10.1016/j.bbamcr.2023.119599

M3 - Review

C2 - 37741575

AN - SCOPUS:85171786421

VL - 1871

JO - B B A - Molecular Cell Research

JF - B B A - Molecular Cell Research

SN - 0167-4889

IS - 1

M1 - 119599

ER -

ID: 391164193