LIFER: Studies on the regulation of lipid flippases (P4 ATPases) by interacting protein partners.

In the LIFER project, supported by Villum Fonden, we are aiming at finding which proteins interact with and regulate plant lipid flippases involved in responses to stress conditions.

As a model, we are using ALA10, and Arabidopsis flippase important for stress responses to phosphate deficiency. This is a major issue in agricultural production as it results in the use of enormous amount of phosphate-containing fertilizers and the pollution of ground-water sources.

Different putative factors regulate the activity of P4 ATPases, including lipids and interacting proteins. What type of proteins interact with plant P4 ATPases? What is the physiological relevance of this interaction?
Different putative factors regulate the activity of P4 ATPases, including lipids and interacting proteins. What type of proteins interact with plant P4 ATPases? What is the physiological relevance of this interaction?

 

 

 

 

Participants

Name Title Phone E-mail
Rosa Laura Lopez Marques Associate professor +45 353-32602 E-mail
Sebastian J Kjeldgaard-Nintemann Senior adviser +45 353-31981 E-mail

Contact

Project leader
Rosa López-Marqués
M: rlo@plen.ku.dk
Ph: +45 35 33 26 02

Funding

The project is funded by Villum Fonden.

Project duration: 1 April 2016 - 15 July 2020.