Epigenetic Memories: The Hidden Drivers of Bacterial Persistence?
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- Epigenetic Memories: The Hidden Drivers of Bacterial Persistence?
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Epigenetic modifications, including DNA methylation, stably alter gene expression without modifying genomic sequences. Recent evidence suggests that epigenetic regulation coupled with a long-term 'memory' effect plays a major role within bacterial persistence formation. Today, emerging high-resolution, single-molecule sequencing technologies allow an increased focus on DNA modifications as regulatory epigenetic marks, which presents a unique opportunity to identify possible epigenetic drivers of bacterial persistence.
Original language | English |
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Journal | Trends in Microbiology |
Volume | 29 |
Issue number | 3 |
Pages (from-to) | 190-194 |
Number of pages | 5 |
ISSN | 0966-842X |
DOIs | |
Publication status | Published - 2021 |
- bacterial persistence, DNA methylation, epigenetic inheritance, gene expression regulation, nanopore sequencing, SMRT sequencing
Research areas
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ID: 258399706