Combined susceptibility and resistance gene-mediated resistance for broad and durable disease resistance in potato

We will explore the effects of combining susceptibility (S)- and resistance (R) gene mediated resistance for obtaining effective and more durable resistance in potato. This involves the use of CRISPR/Cas (S gene loss-of-function) and cis-genesis (R gene gain-of-function) and later monitoring susceptibility towards the late and early blight pest and other pests, e.g. using detached leaf assays or chamber incubations.

Aim: We will evaluate the effects of combining susceptibility (S)- and resistance (R) gene mediated resistance for obtaining effective and more durable resistance in potato.

We expect that results gathered throughout 2026 will enable us to assess these effects by end 2026 or first half of 2027.

For further reference, see this report on Mutations introduced in susceptibility genes through CRISPR/Cas9 genome editing confer increased late blight resistance in potatoes.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

Funded by:

Project: Combined susceptibility and resistance gene-mediated resistance for broad and durable disease resistance in potato
Period:  01.01.2026 - 31.12.2026

Project leader and grant holder

Staffan Persson
Professor
UCPH-PLEN
staffan.persson@plen.ku.dk 
+45 35 32 13 52

Joint project leader

Bent Larsen Petersen 
Research Scientist
KMC amba, with affiliation to PLEN-UCPH
blp@plen.ku.dk 
+45 35 33 33 79