MicroProtein-mediated recruitment of CONSTANS into a TOPLESS trimeric complex represses flowering in Arabidopsis

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Standard

MicroProtein-mediated recruitment of CONSTANS into a TOPLESS trimeric complex represses flowering in Arabidopsis. / Graeff, Moritz; Straub, Daniel; Eguen, Tenai E.; Dolde, Ulla Margrit; Rodrigues, Vandasue Lily; Brandt, Ronny; Wenkel, Stephan.

I: P L o S Genetics, Bind 12, Nr. 3, e1005959, 2016.

Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt

Harvard

Graeff, M, Straub, D, Eguen, TE, Dolde, UM, Rodrigues, VL, Brandt, R & Wenkel, S 2016, 'MicroProtein-mediated recruitment of CONSTANS into a TOPLESS trimeric complex represses flowering in Arabidopsis', P L o S Genetics, bind 12, nr. 3, e1005959. https://doi.org/10.1371/journal.pgen.1005959

APA

Graeff, M., Straub, D., Eguen, T. E., Dolde, U. M., Rodrigues, V. L., Brandt, R., & Wenkel, S. (2016). MicroProtein-mediated recruitment of CONSTANS into a TOPLESS trimeric complex represses flowering in Arabidopsis. P L o S Genetics, 12(3), [e1005959]. https://doi.org/10.1371/journal.pgen.1005959

Vancouver

Graeff M, Straub D, Eguen TE, Dolde UM, Rodrigues VL, Brandt R o.a. MicroProtein-mediated recruitment of CONSTANS into a TOPLESS trimeric complex represses flowering in Arabidopsis. P L o S Genetics. 2016;12(3). e1005959. https://doi.org/10.1371/journal.pgen.1005959

Author

Graeff, Moritz ; Straub, Daniel ; Eguen, Tenai E. ; Dolde, Ulla Margrit ; Rodrigues, Vandasue Lily ; Brandt, Ronny ; Wenkel, Stephan. / MicroProtein-mediated recruitment of CONSTANS into a TOPLESS trimeric complex represses flowering in Arabidopsis. I: P L o S Genetics. 2016 ; Bind 12, Nr. 3.

Bibtex

@article{45d112190330468f8a084d04d06effd5,

title = "MicroProtein-mediated recruitment of CONSTANS into a TOPLESS trimeric complex represses flowering in Arabidopsis",

abstract = "MicroProteins are short, single domain proteins that act by sequestering larger, multi-domain proteins into non-functional complexes. MicroProteins have been identified in plants and animals, where they are mostly involved in the regulation of developmental processes. Here we show that two Arabidopsis thaliana microProteins, miP1a and miP1b, physically interact with CONSTANS (CO) a potent regulator of flowering time. The miP1a/b-type microProteins evolved in dicotyledonous plants and have an additional carboxy-terminal PF(V/L)FL motif. This motif enables miP1a/b microProteins to interact with TOPLESS/TOPLESS-RELATED (TPL/TPR) proteins. Interaction of CO with miP1a/b/TPL causes late flowering due to a failure in the induction of FLOWERING LOCUS T (FT) expression under inductive long day conditions. Both miP1a and miP1b are expressed in vascular tissue, where CO and FT are active. Genetically, miP1a/b act upstream of CO thus our findings unravel a novel layer of flowering time regulation via microProtein-inhibition.",

author = "Moritz Graeff and Daniel Straub and Eguen, {Tenai E.} and Dolde, {Ulla Margrit} and Rodrigues, {Vandasue Lily} and Ronny Brandt and Stephan Wenkel",

year = "2016",

doi = "10.1371/journal.pgen.1005959",

language = "English",

volume = "12",

journal = "P L o S Genetics",

issn = "1553-7390",

publisher = "Public Library of Science",

number = "3",

}

RIS

TY - JOUR

T1 - MicroProtein-mediated recruitment of CONSTANS into a TOPLESS trimeric complex represses flowering in Arabidopsis

AU - Graeff, Moritz

AU - Straub, Daniel

AU - Eguen, Tenai E.

AU - Dolde, Ulla Margrit

AU - Rodrigues, Vandasue Lily

AU - Brandt, Ronny

AU - Wenkel, Stephan

PY - 2016

Y1 - 2016

N2 - MicroProteins are short, single domain proteins that act by sequestering larger, multi-domain proteins into non-functional complexes. MicroProteins have been identified in plants and animals, where they are mostly involved in the regulation of developmental processes. Here we show that two Arabidopsis thaliana microProteins, miP1a and miP1b, physically interact with CONSTANS (CO) a potent regulator of flowering time. The miP1a/b-type microProteins evolved in dicotyledonous plants and have an additional carboxy-terminal PF(V/L)FL motif. This motif enables miP1a/b microProteins to interact with TOPLESS/TOPLESS-RELATED (TPL/TPR) proteins. Interaction of CO with miP1a/b/TPL causes late flowering due to a failure in the induction of FLOWERING LOCUS T (FT) expression under inductive long day conditions. Both miP1a and miP1b are expressed in vascular tissue, where CO and FT are active. Genetically, miP1a/b act upstream of CO thus our findings unravel a novel layer of flowering time regulation via microProtein-inhibition.

AB - MicroProteins are short, single domain proteins that act by sequestering larger, multi-domain proteins into non-functional complexes. MicroProteins have been identified in plants and animals, where they are mostly involved in the regulation of developmental processes. Here we show that two Arabidopsis thaliana microProteins, miP1a and miP1b, physically interact with CONSTANS (CO) a potent regulator of flowering time. The miP1a/b-type microProteins evolved in dicotyledonous plants and have an additional carboxy-terminal PF(V/L)FL motif. This motif enables miP1a/b microProteins to interact with TOPLESS/TOPLESS-RELATED (TPL/TPR) proteins. Interaction of CO with miP1a/b/TPL causes late flowering due to a failure in the induction of FLOWERING LOCUS T (FT) expression under inductive long day conditions. Both miP1a and miP1b are expressed in vascular tissue, where CO and FT are active. Genetically, miP1a/b act upstream of CO thus our findings unravel a novel layer of flowering time regulation via microProtein-inhibition.

U2 - 10.1371/journal.pgen.1005959

DO - 10.1371/journal.pgen.1005959

M3 - Journal article

C2 - 27015278

VL - 12

JO - P L o S Genetics

JF - P L o S Genetics

SN - 1553-7390

IS - 3

M1 - e1005959

ER -

ID: 160405846