Developing human biomonitoring as a 21st century toolbox within the European exposure science strategy 2020–2030
Publikation: Bidrag til tidsskrift › Tidsskriftartikel › Forskning › fagfællebedømt
Human biomonitoring (HBM) is a crucial approach for exposure assessment, as emphasised in the European Commission's Chemicals Strategy for Sustainability (CSS). HBM can help to improve chemical policies in five major key areas: (1) assessing internal and aggregate exposure in different target populations; 2) assessing exposure to chemicals across life stages; (3) assessing combined exposure to multiple chemicals (mixtures); (4) bridging regulatory silos on aggregate exposure; and (5) enhancing the effectiveness of risk management measures. In this strategy paper we propose a vision and a strategy for the use of HBM in chemical regulations and public health policy in Europe and beyond. We outline six strategic objectives and a roadmap to further strengthen HBM approaches and increase their implementation in the regulatory risk assessment of chemicals to enhance our understanding of exposure and health impacts, enabling timely and targeted policy interventions and risk management. These strategic objectives are: 1) further development of sampling strategies and sample preparation; 2) further development of chemical-analytical HBM methods; 3) improving harmonisation throughout the HBM research life cycle; 4) further development of quality control / quality assurance throughout the HBM research life cycle; 5) obtain sustained funding and reinforcement by legislation; and 6) extend target-specific communication with scientists, policymakers, citizens and other stakeholders. HBM approaches are essential in risk assessment to address scientific, regulatory and societal challenges. HBM requires full and strong support from the scientific and regulatory domain to reach its full potential in public and occupational health assessment and in regulatory decision-making.
Originalsprog | Engelsk |
---|---|
Artikelnummer | 107476 |
Tidsskrift | Environment International |
Vol/bind | 168 |
ISSN | 0160-4120 |
DOI | |
Status | Udgivet - 2022 |
Eksternt udgivet | Ja |
Bibliografisk note
Funding Information:
The authors are grateful to all experts from academia, institutes and industry that have participated in discussions that helped formulate the present strategy paper. They would also like to thank ISES Europe for initiating the discussions to prepare a European Exposure Science Strategy 2030. The German Federal Institute for Occupational Safety and Health (BauA), National Institute for Public Health and the Environment (RIVM) and the European Commission Joint Research Centre (JRC) are also acknowledged for each hosting of a meeting in 2018, 2019 and 2020 respectively during which the foundations of the current strategy were built. The views expressed are those of the authors alone and do not necessarily reflect those of the organisations at which they are employed.
Publisher Copyright:
© 2022 The Authors
ID: 333776404