Circular biomanufacturing through harvesting solar energy and CO2
Publikation: Bidrag til tidsskrift › Review › Forskning › fagfællebedømt
Using synthetic biology, it is now time to expand the biosynthetic repertoire of plants and microalgae by utilizing the chloroplast to augment the production of desired high-value compounds and of oil-, carbohydrate-, or protein-enriched biomass based on direct harvesting of solar energy and the consumption of CO2. Multistream product lines based on separate commercialization of the isolated high-value compounds and of the improved bulk products increase the economic potential of the light-driven production system and accelerate commercial scale up. Here we outline the scientific basis for the establishment of such green circular biomanufacturing systems and highlight recent results that make this a realistic option based on cross-disciplinary basic and applied research to advance long-term solutions.
| Originalsprog | Engelsk |
|---|---|
| Tidsskrift | Trends in Plant Science |
| Vol/bind | 27 |
| Udgave nummer | 7 |
| Sider (fra-til) | 655-673 |
| Antal sider | 19 |
| ISSN | 1360-1385 |
| DOI | |
| Status | Udgivet - 2022 |
Bibliografisk note
Funding Information:
This work was supported by the VILLUM Center for Plant Plasticity ( VKR023054 ) (B.L.M.), the European Research Council Advanced Grant ( ERC-2012-ADG 20120314 ) (B.L.M.), the Lundbeck Foundation ( R223-2016-85 , ‘Brewing diterpenoids’) (B.L.M.), the Novo Nordisk Foundation Interdisciplinary Synergy ( NNF 16OC0021616 , ‘Desert-loving therapeutics’) and Distinguished Investigator 2019 ( NNF 0054563 , ‘The black holes in the plant universe’) (B.L.M.) programs, a Novo Nordisk Foundation Emerging Investigator 2020 ( NNF 20OC0061048 , SunMade: Engineering the eukaryotic algae N. oceanica for sustainable bioproduction) (JOAR) grant, and a Novo Nordisk Foundation Plant Science , Agriculture and Food Biotechnology-Post Doctoral Fellowship ( 0071074 ) (M.S.). B.H. thanks the Australian Research Council and AstraZeneca for financial support (LP170100717, Light driven P450: using photosynthesis to power fine chemical production) as well as Elizabeth Gillam and Ian Ross (The University of Queensland) for research support. B.H. also thanks the Australian Research Council and FKG for financial support and the project partners for in kind support (LP180100269, The integrated bio-economy project and the controlled biosphere). The authors thank Dr Javiera Patricia Aravena Calvo, Draw My Science, www.drawmyscience.com , for valuable inputs and for making Figures 1, 5, and 6 .
Funding Information:
This work was supported by the VILLUM Center for Plant Plasticity (VKR023054) (B.L.M.), the European Research Council Advanced Grant (ERC-2012-ADG 20120314) (B.L.M.), the Lundbeck Foundation (R223-2016-85, ‘Brewing diterpenoids’) (B.L.M.), the Novo Nordisk Foundation Interdisciplinary Synergy (NNF 16OC0021616, ‘Desert-loving therapeutics’) and Distinguished Investigator 2019 (NNF 0054563, ‘The black holes in the plant universe’) (B.L.M.) programs, a Novo Nordisk Foundation Emerging Investigator 2020 (NNF 20OC0061048, SunMade: Engineering the eukaryotic algae N. oceanica for sustainable bioproduction) (JOAR) grant, and a Novo Nordisk Foundation Plant Science, Agriculture and Food Biotechnology-Post Doctoral Fellowship (0071074) (M.S.). B.H. thanks the Australian Research Council and AstraZeneca for financial support (LP170100717, Light driven P450: using photosynthesis to power fine chemical production) as well as Elizabeth Gillam and Ian Ross (The University of Queensland) for research support. B.H. also thanks the Australian Research Council and FKG for financial support and the project partners for in kind support (LP180100269, The integrated bio-economy project and the controlled biosphere). The authors thank Dr Javiera Patricia Aravena Calvo, Draw My Science, www.drawmyscience.com, for valuable inputs and for making Figures 1, 5, and 6. No interests are declared.
Publisher Copyright:
© 2022 Elsevier Ltd
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