Thomas Günther-Pomorski

Thomas Günther-Pomorski

Professor


  1. Published

    Biophysical study of resin acid effects on phospholipid membrane structure and properties

    Jagalski, V., Barker, R., Topgaard, D., Pomorski, Thomas Guenther, Hamberger, B. R. & Cardenas Gomez, M., 2016, In: BBA Biomembranes. 1858, 11, p. 2827-2838 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Measuring H+ pumping and membrane potential formation in sealed membrane vesicle systems

    Wielandt, A. G., Palmgren, Michael, Fuglsang, Anja Thoe, Pomorski, Thomas Guenther & Justesen, B. H., 2016, P-Type ATPases: methods and protocols. Bublitz, M. (ed.). Springer, Vol. Part II. p. 171-180 10 p. (Methods in Molecular Biology, Vol. 1377).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  3. Published

    Chromatographic and electrophoretic methods for nanodisc purification and analysis

    Justesen, B. H. & Pomorski, Thomas Guenther, 2014, In: Reviews in Analytical Chemistry. 33, 3, p. 165-172 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    P4-ATPases: lipid flippases in cell membranes

    Lopez Marques, Rosa Laura, Theorin, L., Palmgren, Michael & Pomorski, Thomas Guenther, 2014, In: Pflügers Archiv - European Journal of Physiology. 466, 7, p. 1227-1240 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Short-chain lipid-conjugated pH sensors for imaging of transporter activities in reconstituted systems and living cells

    Kuehnel, R. M., Grifell-Junyent, M., Jørgensen, I. L., Kemmer, G. C., Schiller, J., Palmgren, Michael, Justesen, B. H. & Pomorski, Thomas Guenther, 2019, In: Analyst. 144, 9, p. 3030-3037

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Label-Free Fluorescence Quantification of Hydrolytic Enzyme Activity on Native Substrates Reveals How Lipase Function Depends on Membrane Curvature

    Bohr, S. S., Thorlaksen, C., Kühnel, R. M., Pomorski, Thomas Guenther & Hatzakis, Nikos, 16 Jun 2020, In: Langmuir. 36, 23, p. 6473-6481 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Small-angle Neutron Scattering Shows that the Solution Structures of the Bacterial Mg2+-Channel CorA are Overall Similar with and without Mg2+ Bound

    Arleth, Lise, Johansen, Nicolai Tidemand, Bengtsen, T., Larsen, A. H., Tidemand, Frederik Grønbæk, Pomorski, Thomas Guenther & Lindorff-Larsen, Kresten, 7 Feb 2020, In: Biophysical Journal. 118, 3, Suppl. 1, p. 12A 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  8. Published

    Single Vesicle Fluorescence-Bleaching Assay for Multi-Parameter Analysis of Proteoliposomes by Total Internal Reflection Fluorescence Microscopy

    Veit, S., Paweletz, L. C., Bohr, S. S., Menon, A. K., Hatzakis, Nikos & Pomorski, Thomas Guenther, 2022, In: ACS applied materials & interfaces. 14, 26, p. 29659−29667 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Visualizing NBD-lipid Uptake in Mammalian Cells by Confocal Microscopy

    Baum, Julia Franziska, Bredegaard, L., Herrera, S. A. & Pomorski, Thomas Guenther, 2023, In: Bio-protocol. 13, 13, 16 p., e4771.

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Anionic Phospholipids Stimulate the Proton Pumping Activity of the Plant Plasma Membrane P-Type H+-ATPase

    Paweletz, L. C., Holtbrügge, S. L., Löb, M., De Vecchis, D., Schäfer, L. V., Pomorski, Thomas Guenther & Justesen, B. H., 2023, In: International Journal of Molecular Sciences. 24, 17, 21 p., 13106.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Novel approach to measure the size of plasma-membrane nanodomains in single molecule localization microscopy

    Ziomkiewicz, I., Sporring, Jon, Pomorski, Thomas Guenther & Schulz, Alexander, 2015, In: Cytometry. Part A. 87, 9, p. 868-877

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Functional implications of the influence of ABCA1 on lipid microenvironment at the plasma membrane: a biophysical study

    Zarubica, A., Plazzo, A. P., Stöckl, M., Trombik, T., Hamon, Y., Müller, P., Pomorski, Thomas Guenther, Hermann, A. & Chimini, G., 2009, In: The FASEB Journal. 23, 6, p. 1775-1785 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Isolation of monodisperse nanodisc-reconstituted membrane proteins using free flow electrophoresis

    Justesen, B. H., Laursen, Tomas, Weber, G., Fuglsang, Anja Thoe, Møller, Birger Lindberg & Pomorski, Thomas Guenther, 2013, In: Analytical Chemistry. 85, 7, p. 3497-3500 4 p.

    Research output: Contribution to journalLetterResearchpeer-review

  14. Published

    Lipid somersaults: uncovering the mechanisms of protein-mediated lipid flipping

    Pomorski, Thomas Guenther & Menon, A. K., 2016, In: Progress in Lipid Research. 64, p. 69-84 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Membrane protein reconstitution into giant unilamellar vesicles: a review on current techniques

    Jørgensen, I. L., Kemmer, G. C. & Pomorski, Thomas Guenther, 2017, In: European Biophysics Journal. 46, 2, p. 103-119 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Synthesis and thermotropic phase behavior of four glycoglycerolipids

    Hogendorf, W. F. J., Jagalski, V., Pomorski, Thomas Guenther, Bols, Mikael, Cardenas Gomez, M. & Pedersen, Christian Marcus, 2013, In: Molecules. 18, 11, p. 13546-13573 28 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  17. Published

    Specific activation of the plant P-type plasma membrane H+-ATPase by lysophospholipids depends on the autoinhibitory N- and C-terminal domains

    Wielandt, A. G., Pedersen, J. T., Falhof, J., Kemmer, G. C., Lund, A., Ekberg, K., Fuglsang, Anja Thoe, Pomorski, Thomas Guenther, Buch-Pedersen, M. J. & Palmgren, Michael, 2015, In: The Journal of Biological Chemistry. 290, 26, p. 16281-16291 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Mg2+-dependent conformational equilibria in CorA and an integrated view on transport regulation

    Johansen, Nicolai Tidemand, Bonaccorsi, M., Bengtsen, T., Nørgrd Larsen, Andreas, Tidemand, Frederik Grønbæk, Pedersen, Martin Cramer, Huda, P., Berndtsson, J., Darwish, T., Yepuri, N. R., Martel, A., Pomorski, Thomas Guenther, Bertarello, A., Sansom, M., Rapp, M., Crehuet, R., Schubeis, T., Lindorff-Larsen, Kresten, Pintacuda, G. & Arleth, Lise, 2022, In: eLife. 11, 35 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Measuring in vitro ATPase Activity with High Sensitivity Using Radiolabeled ATP

    Veit, S. & Pomorski, Thomas Guenther, 2023, In: Bio-protocol. 13, 10, 14 p., e4676.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Synthesis and Purification of Lipid-conjugated Fluorescent pH Sensors

    Wiesner, W., Kühnel, R. M. & Pomorski, Thomas Guenther, 2023, In: Bio-protocol. 13, 11, e4694.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Oxetane ring formation in taxol biosynthesis is catalyzed by a bifunctional cytochrome P450 enzyme

    Zhao, Yong, zpm303, zpm303, Xie, Yuman, Duan, Y. T., Andeadelli, A., Pateraki, Irini, Makris, A. M., Pomorski, Thomas Guenther, Stærk, Dan & Kampranis, Sotirios, 2024, In: Journal of the American Chemical Society. 146, p. 801-810

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Cover Feature: LEGO-Inspired Drug Design: Unveiling a Class of Benzo[d ]thiazoles Containing a 3,4-Dihydroxyphenyl Moiety as Plasma Membrane H+ -ATPase Inhibitors (ChemMedChem 1/2018)

    Tung, T., Dao, T. T., Junyent, M. G., Palmgren, Michael, Pomorski, Thomas Guenther, Fuglsang, Anja Thoe, Christensen, Søren Brøgger & Nielsen, J., 8 Jan 2018, In: ChemMedChem. 13, 1, 2 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    In vitro Assay to Evaluate Cation Transport of Ionophores

    Uzun, Huriye Deniz, Vázquez-Hernández, M., Bandow, J. & Pomorski, Thomas Guenther, 2022, In: Bio-protocol. 12, 22, 11 p., e4552.

    Research output: Contribution to journalJournal articleResearchpeer-review

  24. Published

    Time-resolved small-angle neutron scattering as a probe for the dynamics of lipid exchange between human lipoproteins and naturally derived membranes

    Maric, S., Lind, T. K., Raida, M. R., Bengtsson, E., Fredrikson, G. N., Rogers, S., Moulin, M., Haertlein, M., Forsyth, V. T., Wenk, M. R., Pomorski, Thomas Guenther, Arnebrant, T., Lund, R. & Cárdenas, M., 2019, In: Scientific Reports. 9, p. 1-14 7591.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    The P5A ATPase Spf1p is stimulated by phosphatidylinositol 4-phosphate and influences cellular sterol homeostasis

    Sørensen, D. M., Holen, H. W., Pedersen, J. T., Martens, Helle Jakobe, Silvestro, D., Stanchev, L. D., Costa, S. R., Pomorski, Thomas Guenther, Lopez Marques, Rosa Laura & Palmgren, Michael, 15 Apr 2019, In: Molecular Biology of the Cell. 30, 9, p. 1069-1084

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    DLC1 activation requires lipid interaction through a polybasic region preceding the RhoGAP domain

    Erlmann, P., Schmid, S., Horenkamp, F. A., Geyer, M., Pomorski, Thomas Guenther & Olayioye, M. A., 2009, In: Molecular Biology of the Cell. 20, 20, p. 4400-4411 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Disruption of the lipid-transporting LdMT-LdRos3 complex in Leishmania donovani affects membrane lipid asymmetry but not host cell invation

    Weingärtner, A., Drobot, B., Herrmann, A., Sánchez-Cañete, M. P., Gamarro, F., Castanys, S. & Pomorski, Thomas Guenther, 2010, In: PLoS ONE. 5, 8, 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Intracellular targeting signals and lipid specificity determinants of the ALA/ALIS P4-ATPase complex reside in the catalytic ALA a-subunit

    Lopez Marques, Rosa Laura, Poulsen, L. R., Hanisch, S., Meffert, K., Buch-Pedersen, M. J., Jakobsen, M. K., Pomorski, Thomas Guenther & Palmgren, Michael, 2010, In: Molecular Biology of the Cell. 21, 5, p. 791-801 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Leishmania promastigotes lack phosphatidylserine but bind annexin V upon permeabilization or miltefosine treatment

    Weingärtner, A., Kemmer, G. C., Müller, F. D., Zampieri, R. A., Schiller, J. & Pomorski, Thomas Guenther, 2012, In: P L o S One. 7, 8, 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    Organization of fluorescent cholesterol analogs in lipid bilayers — Lessons from cyclodextrin extraction

    Milles, S., Meyer, T., Scheidt, H. A., Schwarzer, R., Thomas, L., Marek, M., Szente, L., Bittman, R., Herrmann, A., Pomorski, Thomas Guenther, Huster, D. & Müller, P., 2013, In: B B A - Biomembranes. 1828, 8, p. 1822-1828 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  31. Published

    Assay of flippase activity in proteoliposomes using fluorescent lipid derivatives

    Marek, M. & Pomorski, Thomas Guenther, 2016, P-Type ATPases: methods and protocols. Bublitz, M. (ed.). Springer, Vol. 2.. p. 181-191 11 p. (Methods in Molecular Biology, Vol. 1377).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  32. Published

    Cell wall staining with Trypan blue enables quantitative analysis of morphological changes in yeast cells

    Liesche, J., Marek, M. & Pomorski, Thomas Guenther, 2015, In: Frontiers in Microbiology. 6, 8 p., 107.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Role of lipid transporters in fungal physiology and pathogenicity

    Rizzo, J., Stanchev, L. D., da Silva, V. K. A., Nimrichter, L., Pomorski, Thomas Guenther & Rodrigues, M. L., 2019, In: Computational and Structural Biotechnology Journal. 17, p. 1278-1289 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  34. Published

    A Fluorescence-based Assay for Measuring Phospholipid Scramblase Activity in Giant Unilamellar Vesicles

    Mathiassen, P. P. M. & Pomorski, Thomas Guenther, 2022, In: Bio-protocol. 12, 6, 19 p., 4366.

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. E-pub ahead of print

    Electroformation of giant unilamellar vesicles from large liposomes

    Uzun, Huriye Deniz, Tiris, Z., Czarnetzki, M., Lopez Marques, Rosa Laura & Pomorski, Thomas Guenther, 2024, (E-pub ahead of print) In: European Physical Journal: Special Topics.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Agrobacterium tumefaciens Small Lipoprotein Atu8019 Is Involved in Selective Outer Membrane Vesicle (OMV) Docking to Bacterial Cells

    Knoke, L. R., Herrera, S. A., Götz, K., Justesen, B. H., Pomorski, Thomas Guenther, Fritz, C., Schäkermann, S., Bandow, J. E. & Aktas, M., 9 Jun 2020, In: Frontiers in Microbiology. 11, 1228.

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    CDC50A is required for aminophospholipid transport and cell fusion in mouse C2C12 myoblasts

    Grifell-Junyent, M., Baum, J. F., Valimets, S., Herrmann, A., Paulusma, C. C., Lopez Marques, Rosa Laura & Pomorski, Thomas Guenther, 2022, In: Journal of Cell Science. 135, 5, jcs258649.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    Imaging of Lipid Uptake in Arabidopsis Seedlings Utilizing Fluorescent Lipids and Confocal Microscopy

    Lopez Marques, Rosa Laura & Pomorski, Thomas Guenther, 2021, In: Bio-protocol. 11, 22, e4228.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Identification of a novel mouse P4-ATPase family member highly expressed during spermatogenesis

    Xu, P., Okkeri, J., Hanisch, S., Hu, R., Xu, Q., Pomorski, Thomas Guenther & Ding, X., 2009, In: Journal of Cell Science. 122, 16, p. 2866-2876 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Pumping lipids with P4-ATPases

    Lopez Marques, Rosa Laura, C.M. Holthuis, J. & Pomorski, Thomas Guenther, 2011, In: Biological Chemistry. 392, 1-2, p. 67-76 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    The yeast plasma membrane ATP binding cassette (ABC) transporter aus1

    Marek, M., Milles, S., Schreiber, G., Daleke, D. L., Dittmar, G., Herrmann, A., Müller, P. & Pomorski, Thomas Guenther, 2011, In: Journal of Biological Chemistry. 286, 24, p. 21835–21843 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Direct observation of proton pumping by a eukaryotic P-type ATPase

    Veshaguri, S., Christensen, S. F., Kemmer, G. C., Ghale, G., Møller, M. P., Lohr, C., Christensen, A. L., Justesen, B. H., Jørgensen, I. L., Schiller, J., Hatzakis, Nikos, Grabe, M., Pomorski, Thomas Guenther & Stamou, Dimitrios, 2016, In: Science. 351, 6280, p. 1469-1473 5 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    The dendrimer impact on vesicles can be tuned based on the lipid bilayer charge and the presence of albumin

    Ruggeri, F., Åkesson, A. K. L., Chapuis, P., Nielsen, Catherine S., Pomorski, Thomas Guenther, Monopoli, M. P., Dawson, K. A., Pomorski, Thomas Guenther & Cardenas Gomez, M., 2013, In: Soft Matter. 9, 37, p. 8862-8870 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    A phospholipid uptake system in the model plant Arabidopsis thaliana

    Poulsen, L. R., Lopez Marques, Rosa Laura, Pedas, P. R., McDowell, S. C., Brown, E., Kunze, R., Harper, J. F., Pomorski, Thomas Guenther & Palmgren, Michael, 2015, In: Nature Communications. 6, 14 p., 7649.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. Published

    A lipid switch unlocks Parkinson's disease-associated ATP13A2

    Holemans, T., Sørensen, D. M., van Veen, S., Martin, S., Hermans, D., Kemmer, G. C., Van den Haute, C., Baekelandt, V., Pomorski, Thomas Guenther, Agostinis, P., Wuytack, F., Palmgren, Michael, Eggermont, J. & Vangheluwe, P., 2015, In: Proceedings of the National Academy of Sciences of the United States of America. 112, 29, p. 9040-9045 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  46. Published

    Functional Significance of Conserved Cysteines in the Extracellular Loops of the ATP Binding Cassette Transporter Pdr11p

    Stanchev, L. D., Marek, M., Xian, F., Klöhn, M., Silvestro, D., Dittmar, G., Lopez Marques, Rosa Laura & Pomorski, Thomas Guenther, 2021, In: Journal of Fungi. 7, 1, 16 p., 2.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    LEGO-inspired drug design: unveiling a class of Benzo[d]thiazoles containing a 3,4-Dihydroxyphenyl moiety as plasma membrane H+-ATPase inhibitors

    Thanh Tung, T., Dao, T. T., Grifell Junyent, M., Palmgren, Michael, Pomorski, Thomas Guenther, Fuglsang, Anja Thoe, Christensen, Søren Brøgger & Nielsen, J., 2018, In: ChemMedChem. 13, 1, 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    NBD-lipid Uptake Assay for Mammalian Cell Lines

    Herrera, S. A., Grifell-Junyent, M. & Pomorski, Thomas Guenther, 2022, In: Bio-protocol. 12, 4, 258649.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    P-type atpase apt1 of the fungal pathogen Cryptococcus neoformans is a lipid flippase of broad substrate specificity

    Stanchev, L. D., Rizzo, J., Peschel, R., Pazurek, L. A., Bredegaard, L., Veit, S., Laerbusch, S., Rodrigues, M. L., Lopez Marques, Rosa Laura & Pomorski, Thomas Guenther, 2021, In: Journal of Fungi. 7, 10, 16 p., 843.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Endoplasmic reticulum phospholipid scramblase activity revealed after protein reconstitution into giant unilamellar vesicles containing a photostable lipid reporter

    Mathiassen, P. P. M., Menon, A. K. & Pomorski, Thomas Guenther, 2021, In: Scientific Reports. 11, 1, 14 p., 14364.

    Research output: Contribution to journalJournal articleResearchpeer-review

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