Søren Bak
Professor
Introductory remarks on publicationslist
ResearcherID H-4404-2014
ORCID 0000-0003-4100-115X
- 2024
- E-pub ahead of print
Site-directed genotype screening for elimination of antinutritional saponins in quinoa seeds identifies TSARL1 as a master controller of saponin biosynthesis selectively in seeds
Trinh, Mai Duy Luu, Visintainer, Davide, Günther, Jan, Østerberg, J. T., Rodrigues da Fonseca, Rute Andreia, Fondevilla, S., Moog, Max William, Luo, Guangbin, Nørrevang, Anton Frisgaard, Crocoll, C., Nielsen, P. V., Jacobsen, S., Wendt, T., Bak, Søren, Lopez Marques, Rosa Laura & Palmgren, Michael, 2024, (E-pub ahead of print) In: Plant Biotechnology Journal. 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Lessons learned from metabolic engineering in hairy roots: Transcriptome and metabolic profile changes caused by Rhizobium-mediated plant transformation in Cucurbitaceae species
Almeida, A., Favero, Bruno Trevenzoli, Dong, L., Cárdenas, Pablo D., Saenz-Mata, J., Lütken, Henrik Vlk & Bak, Søren, Aug 2023, In: Plant Physiology and Biochemistry. 201, 8 p., 107797.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biosynthesis and biotechnological production of the anti-obesity agent celastrol
Zhao, Yong, Hansen, N. L., Duan, Yaotao, Prasad, M., Motawie, Mohammed Saddik, Møller, Birger Lindberg, Pateraki, Irini, Stærk, Dan, Bak, Søren, Miettinen, Karel & Kampranis, Sotirios, 2023, In: Nature Chemistry. 15, p. 1236–1246Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phytoalexins of the crucifer Barbarea vulgaris: Structural profile and correlation with glucosinolate turnover
Cárdenas, Pablo D., Landtved, J. P., Larsen, S. H., Lindegaard, Nicolai, Wøhlk, S., Jensen, Karen Rysbjerg, Pattison, David, Burow, Meike, Bak, Søren, Crocoll, C. & Agerbirk, Niels, 2023, In: Phytochemistry. 213, 17 p., 113742.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pollen-feeding delays reproductive senescence and maintains toxicity of Heliconius erato
Castro, E. C. P. D., McPherson, J., Jullian, G., Mattila, A. L. K., Bak, Søren, Montgomery, S. H. & Jiggins, C., 2023, bioRxiv, 18 p.Research output: Working paper › Preprint
- Published
The saponin bomb: a nucleolar-localized β-glucosidase hydrolyzes triterpene saponins in Medicago truncatula
Lacchini, E., Erffelinck, M., Mertens, J., Marcou, S., Molina-Hidalgo, F. J., Tzfadia, O., Venegas-Molina, J., Cárdenas, Pablo D., Pollier, J., Tava, A., Bak, Søren, Höfte, M. & Goossens, A., 2023, In: New Phytologist. 239, 2, 15 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
A GPCR-based yeast biosensor for biomedical, biotechnological, and point-of-use cannabinoid determination
Miettinen, Karel, Leelahakorn, Nattawat, Almeida Robles, A. R., Zhao, Yong, Hansen, L. R., Nikolajsen, I. E., Andersen, Jens Bo, Givskov, Michael, Stærk, Dan, Bak, Søren & Kampranis, Sotirios, 2022, In: Nature Communications. 13, 16 p., 3664.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolic engineering of cucurbitacins in Cucurbita pepo hairy roots
Almeida, A., Dong, L., Thorsen, T. H., Raadam, Morten Hessellund, Khakimov, Bekzod, Carreno-Quintero, N., Kampranis, Sotirios & Bak, Søren, 2022, In: Frontiers in Plant Science. 13, 18 p., 1021907.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reciprocal mutations of two multifunctional β-amyrin synthases from Barbarea vulgaris shift α/β-amyrin ratios
Günther, Jan, Erthmann, P. O., Khakimov, Bekzod & Bak, Søren, 2022, In: Plant Physiology. 188, 3, p. 1483-1495Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The saponin bomb
Erffelinck, M., Mertens, J., Lacchini, E., Molina-Hidalgo, F. J., Tzfadia, O., Cárdenas, Pablo D., Pollier, J., Tava, A., Bak, Søren & Goossens, A., 2022, Research Square, 33 p.Research output: Working paper › Preprint
- 2021
- Published
An independent evolutionary origin for insect deterrent cucurbitacins in Iberis amara
Dong, L., Almeida Robles, A. R., Pollier, J., Khakimov, Bekzod, Bassard, J. A., Miettinen, K., Stærk, Dan, Mehran, R., Olsen, C. E., Motawie, Mohammed Saddik, Goossens, A. & Bak, Søren, 2021, In: Molecular Biology and Evolution. 38, 11, p. 4659-4673 15 p., msab213.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cascading effects of root microbial symbiosis on the development and metabolome of the insect herbivore Manduca sexta L.
Papantoniou, D., Vergara, F., Weinhold, A., Quijano, T., Khakimov, Bekzod, Pattison, David, Bak, Søren, van Dam, N. M. & Martínez-Medina, A., 2021, In: Metabolites. 11, 11, 23 p., 731.Research output: Contribution to journal › Review › Research › peer-review
- Published
Effects of a saponin-based insect resistance and a systemic pathogen resistance on field performance of the wild crucifer Barbarea vulgaris
Hauser, T. P., Christensen, S., Kuzina, V., Thines, M., Ploch, S. & Bak, Søren, 2021, In: Arthropod-Plant Interactions. 15, p. 683-698Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phenotypic plasticity in chemical defence of butterflies allows usage of diverse host plants
De Castro, É. C. P., Musgrove, J., Bak, Søren, McMillan, W. O. & Jiggins, C. D., 2021, In: Biology Letters. 17, 3, 6 p., 20200863.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
The dynamics of cyanide defences in the life cycle of an aposematic butterfly: Biosynthesis versus sequestration
Pinheiro de Castro, É. C., Demirtas, R., Orteu, A., Olsen, C. E., Motawie, Mohammed Saddik, Zikan Cardoso, M., Zagrobelny, Mika & Bak, Søren, Jan 2020, In: Insect Biochemistry and Molecular Biology. 116, p. 1-9 103259.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Integrating pathway elucidation with yeast engineering to produce polpunonic acid the precursor of the anti-obesity agent celastrol
Hansen, N. L., Miettinen, Karel, Zhao, Yong, Ignea, C., Andreadeli, A., Raadam, Morten Hessellund, Makris, A. M., Møller, Birger Lindberg, Stærk, Dan, Bak, Søren & Kampranis, Sotirios, 2020, In: Microbial Cell Factories. 19, 17 p., 15.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phenotypic plasticity in chemical defence allows butterflies to diversify host use strategies
Castro, É. C. P. D., Musgrove, J., Bak, Søren, McMillan, W. O. & Jiggins, C. D., 2020, bioRxiv, 14 p.Research output: Working paper › Preprint
- Published
Plant triterpenoids with bond-missing skeletons: biogenesis, distribution and bioactivity
Almeida, A., Dong, L., Appendino, G. & Bak, Søren, 2020, In: Natural Product Reports. 37, 22 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Variation of chemical compounds in wild Heliconiini reveals ecological factors involved in the evolution of chemical defenses in mimetic butterflies
Sculfort, O., de Castro, E. C. P., Kozak, K. M., Bak, Søren, Elias, M., Nay, B. & Llaurens, V., 2020, In: Ecology and Evolution. 10, 5, p. 2677-2694 18 p.Research output: Contribution to journal › Review › Research › peer-review
- 2019
- Published
Sequestration and biosynthesis of cyanogenic glucosides in passion vine butterflies and consequences for the diversification of their host plants
Pinheiro de Castro, É. C., Zagrobelny, Mika, Zurano, J. P., Zikan Cardoso, M., Feyereisen, R. & Bak, Søren, 1 May 2019, In: Ecology and Evolution. 9, 9, p. 5079-5093Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The cytochrome P450 CYP72A552 is key to production of hederagenin‐based saponins that mediate plant defense against herbivores
Liu, Q., Khakimov, Bekzod, Cárdenas, Pablo D., Cozzi, F., Olsen, C. E., Jensen, Karen Rysbjerg, Hauser, T. P. & Bak, Søren, May 2019, In: New Phytologist (Online). 222, 3, p. 1599-1609Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Evolution of Structural Diversity of Triterpenoids
Cárdenas, Pablo D., Almeida, A. & Bak, Søren, 2019, In: Frontiers in Plant Science. 10, p. 1-10 1523.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Sequestration and functional diversification of cyanogenic glucosides in the life cycle of Heliconius melpomene
Castro, É. C. P. D., Demirtas, R., Orteu, A., Olsen, C. E., Motawie, Mohammed Saddik, Cardoso, M. Z., Zagrobelny, Mika & Bak, Søren, 2019, bioRxiv, 31 p.Research output: Working paper › Preprint
- 2018
- Published
A Single Oxidosqualene Cyclase Produces the Seco-Triterpenoid α-Onocerin
Almeida, A., Dong, L., Khakimov, Bekzod, Bassard, J. A., Moses, T., Lota, F., Goossens, A., Appendino, G. & Bak, Søren, 2018, In: Plant Physiology. 176, 2, p. 1469-1484 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A tandem array of UDP-glycosyltransferases from the UGT73C subfamily glycosylate sapogenins, forming a spectrum of mono- and bisdesmosidic saponins
Erthmann, P. Ø., Agerbirk, Niels & Bak, Søren, 2018, In: Plant Molecular Biology. 97, 1-2, p. 37-55 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Co-expression of squalene epoxidases with triterpene cyclases boosts production of triterpenoids in plants and yeast
Dong, L., Pollier, J., Bassard, J., Ntallas, G., Almeida, A., Lazaridi, E., Khakimov, Bekzod, Arendt, P., de Oliveira, L. S., Lota, F., Goossens, A., Michoux, F. & Bak, Søren, 2018, In: Metabolic Engineering. 49, p. 1-12Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cyanogenesis in arthropods: from chemical warfare to nuptial gifts
Zagrobelny, Mika, Pinheiro de Castro, É. C., Møller, Birger Lindberg & Bak, Søren, 2018, In: Insects. 9, 2, 39 p., 51.Research output: Contribution to journal › Review › Research › peer-review
- Published
Evolution of the biosynthetic pathway for cyanogenic glucosides in Lepidoptera
Zagrobelny, Mika, Jensen, M. K., Vogel, H., Feyereisen, R. & Bak, Søren, 2018, In: Journal of Molecular Evolution. 86, 6, p. 379-394 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Glucosinolate turnover in Brassicales species to an oxazolidin-2-one, formed via the 2-thione and without formation of thioamide
Agerbirk, Niels, Matthes, A., Erthmann, P. Ø., Ugolini, L., Cinti, S., Lazaridi, E., Nuzillard, J., Mueller, C., Bak, Søren, Rollin, P. & Lazzeri, L., 2018, In: Phytochemistry. 153, p. 79-93Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The TriForC database: a comprehensive up-to-date resource of plant triterpene biosynthesis
Miettinen, Karel, Inigo, S., Kreft, L., Pollier, J., De Bo, C., Botzki, A., Coppens, F., Bak, Søren & Goossens, A., 2018, In: Nucleic Acids Research. 46, D1, p. D586-D594 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The arms race between heliconiine butterflies and Passiflora plants - new insights on an ancient subject
Pinheiro de Castro, É. C., Zagrobelny, Mika, Cardoso, M. Z. & Bak, Søren, 2018, In: Biological Reviews. 93, 1, p. 555-573 19 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Triterpene Messages from the EU-FP7 Project TriForC
Goossens, A., Osbourn, A., Michoux, F. & Bak, Søren, 2018, In: Trends in Plant Science. 23, 4, p. 273-276Research output: Contribution to journal › Editorial › Research › peer-review
- 2017
- Published
Developmentally regulated glucosylation of bitter triterpenoid in cucumber by the Udp-Glucosyltransferase Ugt73am3
Zhong, Y., Xue, X., Liu, Z., Ma, Y., Zeng, K., Han, L., Qi, J., Ro, D., Bak, Søren, Huang, S., Zhou, Y. & Shang, Y., 2017, In: Molecular Plant. 10, 7, p. 1000-1003 4 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Quinoa seed coats as an expanding and sustainable source of bioactive compounds: an investigation of genotypic diversity in saponin profiles
Ruiz, K. B., Khakimov, Bekzod, Engelsen, Søren Balling, Bak, Søren, Biondi, S. & Jacobsen, S., 2017, In: Industrial Crops and Products. 104, p. 156-163 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Spatial separation of the cyanogenic β-glucosidase ZfBGD2 and cyanogenic glucosides in the haemolymph of Zygaena larvae facilitates cyanide release
Pentzold, S., Jensen, M. K., Matthes, A., Olsen, C. E., Petersen, Bent L, Clausen, Henrik, Møller, Birger Lindberg, Bak, Søren & Zagrobelny, Mika, 2017, In: Royal Society Open Science. 4, 13 p., 170262.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The genome sequence of Barbarea vulgaris facilitates the study of ecological biochemistry
Byrne, S. L., Erthmann, P. Ø., Agerbirk, Niels, Bak, Søren, Hauser, T. P., Nagy, I., Paina, C. & Asp, T., 2017, In: Scientific Reports. 7, 14 p., 40728.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Lepidopteran defence droplets - a composite physical and chemical weapon against potential predators
Pentzold, S., Zagrobelny, Mika, Khakimov, Bekzod, Engelsen, Søren Balling, Clausen, Henrik, Petersen, Bent L, Borch, J., Møller, Birger Lindberg & Bak, Søren, 2016, In: Scientific Reports. 6, 11 p., 22407 .Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Screening for triterpenoid saponins in plants using hyphenated analytical platforms
Khakimov, Bekzod, Tseng, L. H., Godejohann, M., Bak, Søren & Engelsen, Søren Balling, 2016, In: Molecules. 21, 12, 19 p., 1614.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Identification and genome organization of saponin pathway genes from a wild crucifer, and their use for transient production of saponins in Nicotiana benthamiana
Khakimov, Bekzod, Poulsen, V. K., Erthmann, P. Ø., Fukushima, E. O., Augustin, J. M., Olsen, C. E., Scholtalbers, J., Volpin, H., Andersen, S. B., Hauser, T. P., Muranaka, T. & Bak, Søren, 2015, In: The Plant Journal. 84, 3, p. 478-490 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolism, excretion and avoidance of cyanogenic glucosides in insects with different feeding specialisations
Pentzold, S., Zagrobelny, Mika, Bjarnholt, Nanna, Kroymann, J., Vogel, H., Olsen, C. E., Møller, Birger Lindberg & Bak, Søren, 2015, In: Insect Biochemistry and Molecular Biology. 66, p. 119-128 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Multiple hydroxyphenethyl glucosinolate isomers and their tandem mass spectrometric destinction in a geographically structured polymorphism in the crucifer Barbarea vulgaris
Agerbirk, Niels, Olsen, C. E., Heimes, C., Christensen, S., Bak, Søren & Hauser, T. P., 2015, In: Phytochemistry. 115, p. 130-142 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The bifurcation of the cyanogenic glucoside and glucosinolate biosynthetic pathways
Sørensen, Mette, Kannangara, R. M., Olsen, C. E., Blomstedt, C. K., Gleadow, R. M., Jørgensen, Kirsten, Bak, Søren, Motawie, Mohammed Saddik & Møller, Birger Lindberg, 2015, In: The Plant Journal. 84, 3, p. 558-573 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Volatiles from the burnet Moth Zygaena filipendulae (Lepidoptera) and Associated flowers, and their involvement in mating communication
Zagrobelny, Mika, Simonsen, H. T., Olsen, C. E., Bak, Søren & Møller, Birger Lindberg, 2015, In: Physiological Entomology. 40, 4, p. 284-295 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Chemical defense balanced by sequestration and de novo biosynthesis in a lepidopteran specialist
Fürstenberg-Hägg, J., Zagrobelny, Mika, Jørgensen, Kirsten, Vogel, H., Møller, Birger Lindberg & Bak, Søren, 2014, In: P L o S One. 9, 10, 9 p., e108745.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-throughput cereal metabolomics: current analytical technologies, challenges and perspectives
Khakimov, Bekzod, Bak, Søren & Engelsen, Søren Balling, 2014, In: Journal of Cereal Science. 59, 3, p. 393-418 26 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
How insects overcome two-component plant chemical defence: plant β-glucosidases as the main target for herbivore adaptation
Pentzold, S., Zagrobelny, Mika, Rook, F. & Bak, Søren, 2014, In: Biological Reviews. 89, 3, p. 531-551 21 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Sequestration, tissue distribution and developmental transmission of cyanogenic glucosides in a specialist insect herbivore
Zagrobelny, Mika, Olsen, C. E., Pentzold, S., Fürstenberg-Hägg, J., Jørgensen, Kirsten, Bak, Søren, Møller, Birger Lindberg & Motawie, Mohammed Saddik, 2014, In: Insect Biochemistry and Molecular Biology. 44, p. 44-53 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The multiple strategies of an insect herbivore to overcome plant cyanogenic glucoside defence
Pentzold, S., Zagrobelny, Mika, Roelsgaard, P. S., Møller, Birger Lindberg & Bak, Søren, 2014, In: PLOS ONE. 9, 3, 8 p., e91337.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptional regulation of de novo biosynthesis of cyanogenic glucosides throughout the life-cycle of the burnet moth Zyagena filipendulae (Lepidoptera)
Fürstenberg-Hägg, J., Zagrobelny, Mika, Olsen, C. E., Jørgensen, Kirsten, Møller, Birger Lindberg & Bak, Søren, 2014, In: Insect Biochemistry and Molecular Biology. 49, p. 80-89 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
Biochemical analysis of a multifunctional cytochrome P450 (CYP51) enzyme required for synthesis of antimicrobial triterpenes in plants
Geisler, K., Hughes, R. K., Sainsbury, F., Lomonossoff, G. P., Rejzek, M., Fairhurst, S., Olsen, C. E., Motawie, Mohammed Saddik, Melton, R. E., Hemmings, A. M., Bak, Søren & Osbourn, A., 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 35, p. E3360-E3367 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 4240264
Most downloads
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5328
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Plant defense against insect herbivores
Research output: Contribution to journal › Review › Research › peer-review
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3234
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UDP-glycosyltransferases from the UGT73C subfamily in Barbarea vulgaris catalyse Sapogenin 3-O-glucosylation in Saponin-mediated Insect resistance
Research output: Contribution to journal › Journal article › Research › peer-review
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2118
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Chemical defense balanced by sequestration and de novo biosynthesis in a lepidopteran specialist
Research output: Contribution to journal › Journal article › Research › peer-review
Published