How can we exploit functional genomics approaches for understanding the nature of plant defences? Barley as a case study
Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › fagfællebedømt
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How can we exploit functional genomics approaches for understanding the nature of plant defences? Barley as a case study. / Collinge, David B.; Jensen, Michael Krogh; Lyngkjær, Michael Foged; Rung, Jesper Henrik.
Sustainable disease management in a European context. Springer, 2008. s. 257-266.Publikation: Bidrag til bog/antologi/rapport › Bidrag til bog/antologi › Forskning › fagfællebedømt
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TY - CHAP
T1 - How can we exploit functional genomics approaches for understanding the nature of plant defences? Barley as a case study
AU - Collinge, David B.
AU - Jensen, Michael Krogh
AU - Lyngkjær, Michael Foged
AU - Rung, Jesper Henrik
PY - 2008
Y1 - 2008
N2 - The concept 'functional genomics' refers to the methods used for the functional characterisation of genomes. The methods utilised provide new opportunities for studying the nature and role of defence mechanisms in plants. Unlike Arabidopsis, poplar and rice, the full genomic sequence of barley is not available. In this case, the analysis of barley gene expression data plays a pivotal role for obtaining insight into the functional characterisation of individual gene products. Many genes are activated transcriptionally following attack by pathogens and these often contribute to the defence mechanisms which underlie disease resistance. The use of large-scale complementary DNA library constructions and genome-wide transcript profiles of plants exposed to biotic stress provide the data required to drive hypotheses concerning the function of newly identified genes. In this paper, we illustrate how publicly available gene expression data has proved valid for studies of plant defence responses; enabling a cost-effective workflow starting from isolated gene transcripts to elucidation of biological function upon biotic stress.
AB - The concept 'functional genomics' refers to the methods used for the functional characterisation of genomes. The methods utilised provide new opportunities for studying the nature and role of defence mechanisms in plants. Unlike Arabidopsis, poplar and rice, the full genomic sequence of barley is not available. In this case, the analysis of barley gene expression data plays a pivotal role for obtaining insight into the functional characterisation of individual gene products. Many genes are activated transcriptionally following attack by pathogens and these often contribute to the defence mechanisms which underlie disease resistance. The use of large-scale complementary DNA library constructions and genome-wide transcript profiles of plants exposed to biotic stress provide the data required to drive hypotheses concerning the function of newly identified genes. In this paper, we illustrate how publicly available gene expression data has proved valid for studies of plant defence responses; enabling a cost-effective workflow starting from isolated gene transcripts to elucidation of biological function upon biotic stress.
KW - Barley
KW - Blumeria graminis f.sp. hordei
KW - Functional genomics
KW - Hordeum vulgare
KW - NAC transcription factors
KW - Pathogen
KW - Plants
U2 - 10.1007/978-1-4020-8780-6_5
DO - 10.1007/978-1-4020-8780-6_5
M3 - Book chapter
AN - SCOPUS:84900888913
SN - 9781402087790
SP - 257
EP - 266
BT - Sustainable disease management in a European context
PB - Springer
ER -
ID: 201511357