The History of the Discovery of Peroxiporins
Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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The History of the Discovery of Peroxiporins. / Henzler, Tobias; Palmgren, Michael Broberg; Bienert, Gerd Patrick.
Peroxiporins: Redox Signal Mediators In and Between Cells. ed. / Iria Medraño-Fernandez; Gerd Patrick Bienert; Roberto Sitia. CRC Press, 2024. p. 215-225.Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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TY - CHAP
T1 - The History of the Discovery of Peroxiporins
AU - Henzler, Tobias
AU - Palmgren, Michael Broberg
AU - Bienert, Gerd Patrick
N1 - Publisher Copyright: © 2024 Iria Medraño-Fernandez, Gerd Patrick Bienert, and Roberto Sitia.
PY - 2024
Y1 - 2024
N2 - Aquaporins represent a member-rich transporter protein family occurring in all kingdoms of life. Aquaporins are channel proteins that form hydrophilic pore pathways across various cellular and subcellular membranes allowing a regulated passage of diverse physiologically relevant molecules. According to functional selectivity features and substrate permeabilities, aquaporins have been designated as aqua-porins, aqua-glycero-porins, aqua-ammonia-porins, metalloido-porins, and peroxi-porins. Peroxiporins comprise those aquaporin isoforms that control hydrogen peroxide membrane permeability and therefore intercellular and interorganellar hydrogen peroxide signaling in living organisms. In this chapter, we describe the very first approaches, experiments, and discoveries, as well as the scientific settings leading to the stepwise functional identification of peroxiporins-the “how it happened”-rather than reviewing in detail the underlying datasets.
AB - Aquaporins represent a member-rich transporter protein family occurring in all kingdoms of life. Aquaporins are channel proteins that form hydrophilic pore pathways across various cellular and subcellular membranes allowing a regulated passage of diverse physiologically relevant molecules. According to functional selectivity features and substrate permeabilities, aquaporins have been designated as aqua-porins, aqua-glycero-porins, aqua-ammonia-porins, metalloido-porins, and peroxi-porins. Peroxiporins comprise those aquaporin isoforms that control hydrogen peroxide membrane permeability and therefore intercellular and interorganellar hydrogen peroxide signaling in living organisms. In this chapter, we describe the very first approaches, experiments, and discoveries, as well as the scientific settings leading to the stepwise functional identification of peroxiporins-the “how it happened”-rather than reviewing in detail the underlying datasets.
U2 - 10.1201/9781003160649-14
DO - 10.1201/9781003160649-14
M3 - Book chapter
AN - SCOPUS:85173331833
SN - 978-0-367-74589-9
SN - 978-0-367-74986-6
SP - 215
EP - 225
BT - Peroxiporins
A2 - Medraño-Fernandez, Iria
A2 - Bienert, Gerd Patrick
A2 - Sitia, Roberto
PB - CRC Press
ER -
ID: 384349173