A structural overview of the plasma membrane Na+,K+-ATPase and H+-ATPase ion pumps

Research output: Contribution to journal › Journal article › Research › peer-review

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A structural overview of the plasma membrane Na+,K+-ATPase and H+-ATPase ion pumps. / Morth, Jens Preben; Pedersen, Bjørn Panella; Buch-Pedersen, Morten Jeppe; Andersen, Jens Peter; Vilsen, Bente; Palmgren, Michael Broberg; Nissen, Poul.

In: Nature Reviews. Molecular Cell Biology, Vol. 12, No. 1, 2011, p. 60-70.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Morth, JP, Pedersen, BP, Buch-Pedersen, MJ, Andersen, JP, Vilsen, B, Palmgren, MB & Nissen, P 2011, 'A structural overview of the plasma membrane Na+,K+-ATPase and H+-ATPase ion pumps', Nature Reviews. Molecular Cell Biology, vol. 12, no. 1, pp. 60-70. https://doi.org/10.1038/nrm3031

APA

Morth, J. P., Pedersen, B. P., Buch-Pedersen, M. J., Andersen, J. P., Vilsen, B., Palmgren, M. B., & Nissen, P. (2011). A structural overview of the plasma membrane Na+,K+-ATPase and H+-ATPase ion pumps. Nature Reviews. Molecular Cell Biology, 12(1), 60-70. https://doi.org/10.1038/nrm3031

Vancouver

Morth JP, Pedersen BP, Buch-Pedersen MJ, Andersen JP, Vilsen B, Palmgren MB et al. A structural overview of the plasma membrane Na+,K+-ATPase and H+-ATPase ion pumps. Nature Reviews. Molecular Cell Biology. 2011;12(1):60-70. https://doi.org/10.1038/nrm3031

Author

Morth, Jens Preben ; Pedersen, Bjørn Panella ; Buch-Pedersen, Morten Jeppe ; Andersen, Jens Peter ; Vilsen, Bente ; Palmgren, Michael Broberg ; Nissen, Poul. / A structural overview of the plasma membrane Na+,K+-ATPase and H+-ATPase ion pumps. In: Nature Reviews. Molecular Cell Biology. 2011 ; Vol. 12, No. 1. pp. 60-70.

Bibtex

@article{fd144cd4a87a4a9788052a32432d01e5,
title = "A structural overview of the plasma membrane Na+,K+-ATPase and H+-ATPase ion pumps",
abstract = "Plasma membrane ATPases are primary active transporters of cations that maintain steep concentration gradients. The ion gradients and membrane potentials derived from them form the basis for a range of essential cellular processes, in particular Na(+)-dependent and proton-dependent secondary transport systems that are responsible for uptake and extrusion of metabolites and other ions. The ion gradients are also both directly and indirectly used to control pH homeostasis and to regulate cell volume. The plasma membrane H(+)-ATPase maintains a proton gradient in plants and fungi and the Na(+),K(+)-ATPase maintains a Na(+) and K(+) gradient in animal cells. Structural information provides insight into the function of these two distinct but related P-type pumps.",
keywords = "Animals, Cell Membrane, Humans, Proton-Translocating ATPases, Sodium-Potassium-Exchanging ATPase",
author = "Morth, {Jens Preben} and Pedersen, {Bj{\o}rn Panella} and Buch-Pedersen, {Morten Jeppe} and Andersen, {Jens Peter} and Bente Vilsen and Palmgren, {Michael Broberg} and Poul Nissen",
year = "2011",
doi = "10.1038/nrm3031",
language = "English",
volume = "12",
pages = "60--70",
journal = "Nature Reviews. Molecular Cell Biology",
issn = "1471-0072",
publisher = "nature publishing group",
number = "1",

}

RIS

TY - JOUR

T1 - A structural overview of the plasma membrane Na+,K+-ATPase and H+-ATPase ion pumps

AU - Morth, Jens Preben

AU - Pedersen, Bjørn Panella

AU - Buch-Pedersen, Morten Jeppe

AU - Andersen, Jens Peter

AU - Vilsen, Bente

AU - Palmgren, Michael Broberg

AU - Nissen, Poul

PY - 2011

Y1 - 2011

N2 - Plasma membrane ATPases are primary active transporters of cations that maintain steep concentration gradients. The ion gradients and membrane potentials derived from them form the basis for a range of essential cellular processes, in particular Na(+)-dependent and proton-dependent secondary transport systems that are responsible for uptake and extrusion of metabolites and other ions. The ion gradients are also both directly and indirectly used to control pH homeostasis and to regulate cell volume. The plasma membrane H(+)-ATPase maintains a proton gradient in plants and fungi and the Na(+),K(+)-ATPase maintains a Na(+) and K(+) gradient in animal cells. Structural information provides insight into the function of these two distinct but related P-type pumps.

AB - Plasma membrane ATPases are primary active transporters of cations that maintain steep concentration gradients. The ion gradients and membrane potentials derived from them form the basis for a range of essential cellular processes, in particular Na(+)-dependent and proton-dependent secondary transport systems that are responsible for uptake and extrusion of metabolites and other ions. The ion gradients are also both directly and indirectly used to control pH homeostasis and to regulate cell volume. The plasma membrane H(+)-ATPase maintains a proton gradient in plants and fungi and the Na(+),K(+)-ATPase maintains a Na(+) and K(+) gradient in animal cells. Structural information provides insight into the function of these two distinct but related P-type pumps.

KW - Animals

KW - Cell Membrane

KW - Humans

KW - Proton-Translocating ATPases

KW - Sodium-Potassium-Exchanging ATPase

U2 - 10.1038/nrm3031

DO - 10.1038/nrm3031

M3 - Journal article

C2 - 21179061

VL - 12

SP - 60

EP - 70

JO - Nature Reviews. Molecular Cell Biology

JF - Nature Reviews. Molecular Cell Biology

SN - 1471-0072

IS - 1

ER -

ID: 44307609