Thomas Günther-Pomorski
Professor
Section for Transport Biology
Thorvaldsensvej 40
1871 Frederiksberg C
- Published
Induced dye leakage by PAMAM G6 does not imply dendrimer entry into vesicle lumen
Åkesson, A. K. L., Lundgaard, C. V., Ehrlich, N., Pomorski, Thomas Guenther, Stamou, Dimitrios & Cardenas Gomez, M., 2012, In: Soft Matter. 8, 34, p. 8972-8980 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel approach to measure the size of plasma-membrane nanodomains in single molecule localization microscopy
Ziomkiewicz, I., Sporring, Jon, Pomorski, Thomas Guenther & Schulz, Alexander, 2015, In: Cytometry. Part A. 87, 9, p. 868-877Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oxetane ring formation in taxol biosynthesis is catalyzed by a bifunctional cytochrome P450 enzyme
Zhao, Yong, zpm303, zpm303, Xie, Yuman, Duan, Y. T., Andeadelli, A., Pateraki, Irini, Makris, A. M., Pomorski, Thomas Guenther, Stærk, Dan & Kampranis, Sotirios, 2024, In: Journal of the American Chemical Society. 146, p. 801-810Research output: Contribution to journal › Journal article › Research › peer-review
Functional implications of the influence of ABCA1 on lipid microenvironment at the plasma membrane: a biophysical study
Zarubica, A., Plazzo, A. P., Stöckl, M., Trombik, T., Hamon, Y., Müller, P., Pomorski, Thomas Guenther, Hermann, A. & Chimini, G., 2009, In: The FASEB Journal. 23, 6, p. 1775-1785 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of a novel mouse P4-ATPase family member highly expressed during spermatogenesis
Xu, P., Okkeri, J., Hanisch, S., Hu, R., Xu, Q., Pomorski, Thomas Guenther & Ding, X., 2009, In: Journal of Cell Science. 122, 16, p. 2866-2876 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synthesis and Purification of Lipid-conjugated Fluorescent pH Sensors
Wiesner, W., Kühnel, R. M. & Pomorski, Thomas Guenther, 2023, In: Bio-protocol. 13, 11, e4694.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Measuring H+ pumping and membrane potential formation in sealed membrane vesicle systems
Wielandt, A. G., Palmgren, Michael, Fuglsang, Anja Thoe, Pomorski, Thomas Guenther & Justesen, B. H., 2016, P-Type ATPases: methods and protocols. Bublitz, M. (ed.). Springer, Vol. Part II. p. 171-180 10 p. (Methods in Molecular Biology, Vol. 1377).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Specific activation of the plant P-type plasma membrane H+-ATPase by lysophospholipids depends on the autoinhibitory N- and C-terminal domains
Wielandt, A. G., Pedersen, J. T., Falhof, J., Kemmer, G. C., Lund, A., Ekberg, K., Fuglsang, Anja Thoe, Pomorski, Thomas Guenther, Buch-Pedersen, M. J. & Palmgren, Michael, 2015, In: The Journal of Biological Chemistry. 290, 26, p. 16281-16291 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Disruption of the lipid-transporting LdMT-LdRos3 complex in Leishmania donovani affects membrane lipid asymmetry but not host cell invation
Weingärtner, A., Drobot, B., Herrmann, A., Sánchez-Cañete, M. P., Gamarro, F., Castanys, S. & Pomorski, Thomas Guenther, 2010, In: PLoS ONE. 5, 8, 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ca2+-activated transbilayer movement of plasma membrane phospholipids in Leishmania donovani during ionomycin or thapsigargin stimulation
Weingärtner, A., Santos, M. G. D., Drobot, B. & Pomorski, Thomas Guenther, 2011, In: Molecular and Biochemical Parasitology. 179, 2, p. 59-68 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Leishmania promastigotes lack phosphatidylserine but bind annexin V upon permeabilization or miltefosine treatment
Weingärtner, A., Kemmer, G. C., Müller, F. D., Zampieri, R. A., Schiller, J. & Pomorski, Thomas Guenther, 2012, In: P L o S One. 7, 8, 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Resolving active ion transport at the single molecule level for the first time
Veshaguri, S., Christensen, S. M., Kemmer, G. C., Møller, M. P., Ghale, G., Lohr, C., Christensen, A. L., Justesen, B. H., Jørgensen, I. L., Schiller, J., Hatzakis, Nikos, Grabe, M., Pomorski, Thomas Guenther & Stamou, Dimitrios, 2016, In: Biophysical Journal. 110, 3, p. 179A 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development of a fluorescence-based assay for functional studies of transporter proteins on the single molecule level
Veshaguri, S., Christensen, S. F., Møller, M. P., Ghale, G., Lohr, C., Christensen, A. L., Tutkus, M., Kemmer, G. C., Jørgensen, I. L., Justesen, B. H., Curran, P., Pomorski, Thomas Guenther, Mindell, J. & Stamou, Dimitrios, 2015, In: Biophysical Journal. 108, 2, Supplement 1, p. 187a 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Functional analysis of proton-transporter at single molecule level
Veshaguri, S., Christensen, S., Ghale, G., Møller, M. P., Lohr, C., Christensen, A. L., Tutkus, M., Kemmer, G. C., Justesen, B. H., Jørgensen, I. L., Pomorski, Thomas Guenther & Stamou, Dimitrios, 2015, In: Biophysical Journal. 108, 2, Supplement 1, p. 147a 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Direct observation of proton pumping by a eukaryotic P-type ATPase
Veshaguri, S., Christensen, S. F., Kemmer, G. C., Ghale, G., Møller, M. P., Lohr, C., Christensen, A. L., Justesen, B. H., Jørgensen, I. L., Schiller, J., Hatzakis, Nikos, Grabe, M., Pomorski, Thomas Guenther & Stamou, Dimitrios, 2016, In: Science. 351, 6280, p. 1469-1473 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A flippase-independent function of ATP8B1, the protein affected in familial intrahepatic cholestasis Type 1, is required for apical protein expression and microvillus formation in polarized epithelial cells
Verhulst, P. M., Velden, L. M. V. D., Oorschot, V., Faassen, E. E. V., Klumperman, J., Houwen, R. H. J., Pomorski, Thomas Guenther, Holthuis, J. C. M. & Klomp, L. W. J., 2010, In: Hepatology. 51, 6, p. 2049-2060 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Measuring in vitro ATPase Activity with High Sensitivity Using Radiolabeled ATP
Veit, S. & Pomorski, Thomas Guenther, 2023, In: Bio-protocol. 13, 10, 14 p., e4676.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Determination of membrane protein orientation upon liposomal reconstitution down to the single vesicle level
Veit, S., Paweletz, L. C. & Pomorski, Thomas Guenther, 2023, In: Biological Chemistry. 404, 7Research output: Contribution to journal › Review › Research › peer-review
- Published
Single Vesicle Fluorescence-Bleaching Assay for Multi-Parameter Analysis of Proteoliposomes by Total Internal Reflection Fluorescence Microscopy
Veit, S., Paweletz, L. C., Bohr, S. S., Menon, A. K., Hatzakis, Nikos & Pomorski, Thomas Guenther, 2022, In: ACS applied materials & interfaces. 14, 26, p. 29659−29667 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional Analysis of the P-Type ATPases Apt2-4 from Cryptococcus neoformans by Heterologous Expression in Saccharomyces cerevisiae
Veit, S., Laerbusch, S., Lopez Marques, Rosa Laura & Pomorski, Thomas Guenther, 2023, In: Journal of Fungi. 9, 2, 16 p., 202.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Electroformation of giant unilamellar vesicles from large liposomes
Uzun, Huriye Deniz, Tiris, Z., Czarnetzki, M., Lopez Marques, Rosa Laura & Pomorski, Thomas Guenther, 2024, (E-pub ahead of print) In: European Physical Journal: Special Topics.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vitro Assay to Evaluate Cation Transport of Ionophores
Uzun, Huriye Deniz, Vázquez-Hernández, M., Bandow, J. & Pomorski, Thomas Guenther, 2022, In: Bio-protocol. 12, 22, 11 p., e4552.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cover Feature: LEGO-Inspired Drug Design: Unveiling a Class of Benzo[d ]thiazoles Containing a 3,4-Dihydroxyphenyl Moiety as Plasma Membrane H+ -ATPase Inhibitors (ChemMedChem 1/2018)
Tung, T., Dao, T. T., Junyent, M. G., Palmgren, Michael, Pomorski, Thomas Guenther, Fuglsang, Anja Thoe, Christensen, Søren Brøgger & Nielsen, J., 8 Jan 2018, In: ChemMedChem. 13, 1, 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The lipid head group is the key element for substrate recognition by the P4 ATPase ALA2: A phosphatidylserine flippase
Theorin, L., Faxén, K., Sørensen, D. M., Migotti, R., Dittmar, G., Schiller, J., Daleke, D. L., Palmgren, Michael, Lopez Marques, Rosa Laura & Pomorski, Thomas Guenther, 6 Mar 2019, In: Biochemical Journal. 476, 5, p. 783-794Research output: Contribution to journal › Journal article › Research › peer-review
- Published
LEGO-inspired drug design: unveiling a class of Benzo[d]thiazoles containing a 3,4-Dihydroxyphenyl moiety as plasma membrane H+-ATPase inhibitors
Thanh Tung, T., Dao, T. T., Grifell Junyent, M., Palmgren, Michael, Pomorski, Thomas Guenther, Fuglsang, Anja Thoe, Christensen, Søren Brøgger & Nielsen, J., 2018, In: ChemMedChem. 13, 1, 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The P5A ATPase Spf1p is stimulated by phosphatidylinositol 4-phosphate and influences cellular sterol homeostasis
Sørensen, D. M., Holen, H. W., Pedersen, J. T., Martens, Helle Jakobe, Silvestro, D., Stanchev, L. D., Costa, S. R., Pomorski, Thomas Guenther, Lopez Marques, Rosa Laura & Palmgren, Michael, 15 Apr 2019, In: Molecular Biology of the Cell. 30, 9, p. 1069-1084Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Metabolic incorporation of unsaturated fatty acids into boar spermatozoa lipids and de novo formation of diacylglycerols
Svetlichnyy, V., Müller, P., Pomorski, Thomas Guenther, Schulze, M., Schiller, J. & Müller, K., 2014, In: Chemistry and Physics of Lipids. 177, p. 41-50 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional Significance of Conserved Cysteines in the Extracellular Loops of the ATP Binding Cassette Transporter Pdr11p
Stanchev, L. D., Marek, M., Xian, F., Klöhn, M., Silvestro, D., Dittmar, G., Lopez Marques, Rosa Laura & Pomorski, Thomas Guenther, 2021, In: Journal of Fungi. 7, 1, 16 p., 2.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
P-type atpase apt1 of the fungal pathogen Cryptococcus neoformans is a lipid flippase of broad substrate specificity
Stanchev, L. D., Rizzo, J., Peschel, R., Pazurek, L. A., Bredegaard, L., Veit, S., Laerbusch, S., Rodrigues, M. L., Lopez Marques, Rosa Laura & Pomorski, Thomas Guenther, 2021, In: Journal of Fungi. 7, 10, 16 p., 843.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Ergosterol is mainly located in the cytoplasmic leaflet of the yeast plasma membrane
Solanko, L. M., Sullivan, D. P., Sere, Y. Y., Szomek, M., Lunding, A., Solanko, K., Pizovic, A., Stanchev, L. D., Pomorski, Thomas Guenther, Menon, A. K. & Wüstner, D., 2018, In: Traffic. 19, 3, p. 198-214 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural requirements for membrane binding of human guanylate-binding protein 1
Sistemich, L., Dimitrov Stanchev, L., Kutsch, M., Roux, A., Pomorski, Thomas Guenther & Herrmann, C., 2021, In: FEBS Journal. 288, 13, p. 4098-4114Research output: Contribution to journal › Journal article › Research › peer-review
Effects of 4-Br-A23187 on Bacillus subtilis cells and unilamellar vesicles reveal it to be a potent copper ionophore
Senges, C. H. R., Warmuth, H. L., Vázquez‐Hernández, M., Uzun, Huriye Deniz, Sagurna, L., Dietze, P., Schmidt, C., Mücher, B., Herlitze, S., Krämer, U., Ott, I., Pomorski, Thomas Guenther & Bandow, J. E., 2022, In: Proteomics. 22, 17, 12 p., 2200061.Research output: Contribution to journal › Journal article › Research › peer-review
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Transbilayer dynamics of phospholipids in the plasma membrane of the Leishmania genus
Santos, M. G. D., Muxel, S. M., Zampieri, R. A., Pomorski, Thomas Guenther & Floeter-Winter, L. M., 2013, In: P L o S One. 8, 1, 7 p., e55604.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The dendrimer impact on vesicles can be tuned based on the lipid bilayer charge and the presence of albumin
Ruggeri, F., Åkesson, A. K. L., Chapuis, P., Nielsen, Catherine S., Pomorski, Thomas Guenther, Monopoli, M. P., Dawson, K. A., Pomorski, Thomas Guenther & Cardenas Gomez, M., 2013, In: Soft Matter. 9, 37, p. 8862-8870 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Role of lipid transporters in fungal physiology and pathogenicity
Rizzo, J., Stanchev, L. D., da Silva, V. K. A., Nimrichter, L., Pomorski, Thomas Guenther & Rodrigues, M. L., 2019, In: Computational and Structural Biotechnology Journal. 17, p. 1278-1289 12 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Novel secretory pathway pumps
Poulsen, L. R., Lopez Marques, Rosa Laura, Sørensen, D. M., Pomorski, Thomas Guenther, Buch Pedersen, M. & Palmgren, Michael, 2010, In: Biochimica et Biophysica Acta - Bioenergetics. 1797, Suppl., p. 42 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
- Published
A phospholipid uptake system in the model plant Arabidopsis thaliana
Poulsen, L. R., Lopez Marques, Rosa Laura, Pedas, P. R., McDowell, S. C., Brown, E., Kunze, R., Harper, J. F., Pomorski, Thomas Guenther & Palmgren, Michael, 2015, In: Nature Communications. 6, 14 p., 7649.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Anionic Phospholipids Stimulate the Proton Pumping Activity of the Plant Plasma Membrane P-Type H+-ATPase
Paweletz, L. C., Holtbrügge, S. L., Löb, M., De Vecchis, D., Schäfer, L. V., Pomorski, Thomas Guenther & Justesen, B. H., 2023, In: International Journal of Molecular Sciences. 24, 17, 21 p., 13106.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Primary cell wall inspired micro containers as a step towards a synthetic plant cell
Paulraj, T., Wennmalm, S., Wieland, D. C. F., Riazanova, A. V., Dėdinaitė, A., Pomorski, Thomas Guenther, Cárdenas, M. & Svagan, A. J., 2020, In: Nature Communications. 11, 1, 11 p., 958.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Bimolecular fluorescence complementation and interaction of various Arabidopsis major intrinsic proteins expressed in yeast
Murozuka, E., Hanisch, S., Pomorski, Thomas Guenther, Jahn, T. P. & Schjoerring, Jan K., 2013, In: Physiologia Plantarum. 148, 3, p. 422-431 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Organization of fluorescent cholesterol analogs in lipid bilayers — Lessons from cyclodextrin extraction
Milles, S., Meyer, T., Scheidt, H. A., Schwarzer, R., Thomas, L., Marek, M., Szente, L., Bittman, R., Herrmann, A., Pomorski, Thomas Guenther, Huster, D. & Müller, P., 2013, In: B B A - Biomembranes. 1828, 8, p. 1822-1828 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Endoplasmic reticulum phospholipid scramblase activity revealed after protein reconstitution into giant unilamellar vesicles containing a photostable lipid reporter
Mathiassen, P. P. M., Menon, A. K. & Pomorski, Thomas Guenther, 2021, In: Scientific Reports. 11, 1, 14 p., 14364.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
A Fluorescence-based Assay for Measuring Phospholipid Scramblase Activity in Giant Unilamellar Vesicles
Mathiassen, P. P. M. & Pomorski, Thomas Guenther, 2022, In: Bio-protocol. 12, 6, 19 p., 4366.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biosynthetic preparation of selectively deuterated phosphatidylcholine in genetically modified Escherichia coli
Maric, S., Thygesen, Mikkel Boas, Schiller, J., Marek, M., Moulin, M., Haertlein, M., Forsyth, V. T., Bogdanov, M., Dowhan, W., Arleth, Lise & Pomorski, Thomas Guenther, 2015, In: Applied Microbiology and Biotechnology. 99, 1, p. 241-254 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Stealth carriers for low-resolution structure determination of membrane proteins in solution
Maric, S., Skar-Gislinge, Nicholas, Midtgaard, S., Thygesen, Mikkel Boas, Schiller, J., Frielinghaus, H., Moulin, M., Haertlein, M., Forsyth, V. T., Pomorski, Thomas Guenther & Arleth, Lise, 2014, In: Acta Crystallographica. Section D: Biological Crystallography. 70, 2, p. 317-328 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Time-resolved small-angle neutron scattering as a probe for the dynamics of lipid exchange between human lipoproteins and naturally derived membranes
Maric, S., Lind, T. K., Raida, M. R., Bengtsson, E., Fredrikson, G. N., Rogers, S., Moulin, M., Haertlein, M., Forsyth, V. T., Wenk, M. R., Pomorski, Thomas Guenther, Arnebrant, T., Lund, R. & Cárdenas, M., 2019, In: Scientific Reports. 9, p. 1-14 7591.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The yeast plasma membrane ATP binding cassette (ABC) transporter aus1
Marek, M., Milles, S., Schreiber, G., Daleke, D. L., Dittmar, G., Herrmann, A., Müller, P. & Pomorski, Thomas Guenther, 2011, In: Journal of Biological Chemistry. 286, 24, p. 21835–21843 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Assay of flippase activity in proteoliposomes using fluorescent lipid derivatives
Marek, M. & Pomorski, Thomas Guenther, 2016, P-Type ATPases: methods and protocols. Bublitz, M. (ed.). Springer, Vol. 2.. p. 181-191 11 p. (Methods in Molecular Biology, Vol. 1377).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
Serum albumin promotes ATP-binding cassette transporter-dependent sterol uptake in yeast
Marek, M., Silvestro, D., Fredslund, M. D., Andersen, T. G. & Pomorski, Thomas Guenther, 2014, In: FEMS Yeast Research. 14, 8, p. 1223-1233 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Imaging of Lipid Uptake in Arabidopsis Seedlings Utilizing Fluorescent Lipids and Confocal Microscopy
Lopez Marques, Rosa Laura & Pomorski, Thomas Guenther, 2021, In: Bio-protocol. 11, 22, e4228.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 9099036
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Leishmania promastigotes lack phosphatidylserine but bind annexin V upon permeabilization or miltefosine treatment
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Lipid-conjugated fluorescent pH sensors for monitoring pH changes in reconstituted membrane systems
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Biologiske pumper og transport i vesikler
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