Tomas Laursen
Associate Professor
Section for Plant Biochemistry
Thorvaldsensvej 40
1871 Frederiksberg C
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Evolution of NADPH-cytochrome P450 oxidoreductases (POR) in Apiales - POR 1 is missing
Andersen, T. B., Hansen, N. B., Laursen, Tomas, Weitzel, C. & Simonsen, H. T., 2016, In: Molecular Phylogenetics and Evolution. 98, p. 21-28 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Natural Deep Eutectic Solvents for functionalization and storage of natural products and enzymes
Baden, C. K., Montini, L., Bassard, J. A., Viborg, K. M., Jørgensen, Kirsten, Bjarnholt, Nanna, Møller, Birger Lindberg & Laursen, Tomas, 15 Jul 2018.Research output: Contribution to conference › Poster › Research
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The binding of UDP-glucosyltransferase to the cytochrome P450s in dhurrin biosynthesis
Baden, C. K., Laursen, Tomas, Kannangara, R. M., Bertram, N., Cardenas Gomez, M. & Møller, Birger Lindberg, 2013. 1 p.Research output: Contribution to conference › Poster › Research
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Dynamic metabolic solutions to the sessile life style of plants
Baden, C. K., Gallage, N. J., Hansen, Cecilie Ida Cetti, Møller, Birger Lindberg & Laursen, Tomas, 2018, In: Natural Product Reports. 35, 11, p. 1140-1155 16 p.Research output: Contribution to journal › Review › Research › peer-review
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Molecular snapshots of dynamic membrane-bound metabolons
Bassard, J. E. & Laursen, Tomas, 1 Jan 2019, Methods in Enzymology. Academic Press, Vol. 617. p. 1-27 27 p. (Methods in Enzymology, Vol. 617).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
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Assembly of dynamic P450-mediated metabolons - order versus chaos
Bassard, J. A., Møller, Birger Lindberg & Laursen, Tomas, 2017, In: Current Biology. 3, 1, p. 37-51 15 p.Research output: Contribution to journal › Review › Research › peer-review
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Direct observation of multiple conformational states in Cytochrome P450 oxidoreductase and their modulation by membrane environment and ionic strength
Bavishi, K., Li, D., Eiersholt, S., Hooley, E. N., Petersen, Troels Christian, Møller, Birger Lindberg, Hatzakis, Nikos & Laursen, Tomas, 2018, In: Scientific Reports. 8, 9 p., 6817.Research output: Contribution to journal › Journal article › Research › peer-review
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Application of nanodisc technology for direct electrochemical investigation of plant cytochrome P450s and their NADPH P450 oxidoreductase
Bavishi, K., Laursen, Tomas, Martinez, Karen Laurence, Møller, Birger Lindberg & Della Pia, E. A., 2016, In: Scientific Reports. 6, 10 p., 29459.Research output: Contribution to journal › Journal article › Research › peer-review
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Nanodisc films for membrane protein studies by neutron reflection: effect of the protein scaffold choice
Bertram, N., Laursen, Tomas, Barker, R., Bavishi, K., Møller, Birger Lindberg & Cardenas Gomez, M., 2015, In: Langmuir. 31, 30, p. 8386-8391 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
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A combined biochemical screen and TILLING approach identifies mutations in Sorghum bicolor L. Moench resulting in acyanogenic forage production
Blomstedt, C. K., Gleadow, R. M., O'Donnell, N., Naur, P., Jensen, K., Laursen, Tomas, Olsen, C. E., Stuart, P., Hamill, J. D., Møller, Birger Lindberg & Neale, A. D., 2012, In: Plant Biotechnology Journal. 10, 1, p. 54-66 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Anthocyanic Vacuolar Inclusions: From Biosynthesis to Storage and Possible Applications
Buhrman, K., Aravena Calvo, Javiera Patricia, Ross Zaulich, C., Hinz, Kasper & Laursen, Tomas, 2022, In: Frontiers in Chemistry. 10, 9 p., 913324.Research output: Contribution to journal › Review › Research › peer-review
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Structure-guided engineering of key amino acids in UGT85B1 controlling substrate and stereo-specificity in aromatic cyanogenic glucoside biosynthesis
Del Giudice, R., Putkaradze, N., dos Santos, B. M., Hansen, Cecilie Ida Cetti, Crocoll, C., Motawie, Mohammed Saddik, Fredslund, F., Laursen, Tomas & Welner, D. H., 2022, In: Plant Journal. 111, 6, p. 1539-1549Research output: Contribution to journal › Journal article › Research › peer-review
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The Three Members of the Arabidopsis Glycosyltransferase Family 92 are Functional β-1,4-Galactan Synthases
Ebert, B., Birdseye, D., Liwanag, A. J. M., Laursen, Tomas, Rennie, E. A., Guo, X., Catena, M., Rautengarten, C., Stonebloom, S. H., Gluza, P., Pidatala, V., Andersen, M. C. F., Cheetamun, R., Mortimer, J. C., Heazlewood, J. L., Bacic, A., Clausen, M. H., Willats, W. G. T. & Scheller, H. V., 2018, In: Plant and Cell Physiology. 59, 12, p. 2624-2636 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Expanding the Toolbox for Bicelle-Forming Surfactant–Lipid Mixtures
Giudice, R. D., Paracini, N., Laursen, Tomas, Blanchet, C., Roosen-Runge, F. & Cárdenas, M., 2022, In: Molecules. 27, 21, 13 p., 7628.Research output: Contribution to journal › Journal article › Research › peer-review
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Functional expression of N-terminally tagged membrane bound cytochrome P450
Hamann, T., Laursen, Tomas & Møller, Birger Lindberg, 2009, In: Protein Expression and Purification. 68, 1, p. 18-21 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Biased metabolism via small-molecule ligands binding to P450 oxidoreductase
Hatzakis, Nikos, Jensen, S. B., Thodberg, S., Parween, S., Moses, M. E., Hansen, C. C., Knudsen, C., Giudice, R. D., Lund, P. M., Castano, P., Bustamante, Y. G., Jorgennsen, F. S., Pandey, A. V., Laursen, Tomas & Møller, Birger Lindberg, 1 Feb 2022, In: Biophysical Journal. 121, 3, p. 52a 1 p., 250-Pos.Research output: Contribution to journal › Conference abstract in journal › Research
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Biased cytochrome P450-mediated metabolism via small-molecule ligands binding P450 oxidoreductase
Jensen, S. B., Thodberg, S., Parween, S., Moses, M. E., Hansen, Cecilie Ida Cetti, Thomsen, J., Sletfjerding, M. B., Knudsen, C., Del Giudice, R., Lund, P. M., Castaño, P. R., Bustamante, Y. G., Velazquez, M. N. R., Jørgensen, Flemming Steen, Pandey, A. V., Laursen, Tomas, Møller, Birger Lindberg & Hatzakis, Nikos, 2021, In: Nature Communications. 12, 1, 14 p., 2260.Research output: Contribution to journal › Journal article › Research › peer-review
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Isolation of monodisperse nanodisc-reconstituted membrane proteins using free flow electrophoresis
Justesen, B. H., Laursen, Tomas, Weber, G., Fuglsang, Anja Thoe, Møller, Birger Lindberg & Pomorski, Thomas Guenther, 2013, In: Analytical Chemistry. 85, 7, p. 3497-3500 4 p.Research output: Contribution to journal › Letter › Research › peer-review
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Stabilization of dhurrin biosynthetic enzymes from Sorghum bicolor using a natural deep eutectic solvent
Knudsen, C., Bavishi, K., Viborg, K. M., Drew, D. P., Simonsen, H. T., Motawie, Mohammed Saddik, Møller, Birger Lindberg & Laursen, Tomas, 2020, In: Phytochemistry. 170, 9 p., 112214.Research output: Contribution to journal › Journal article › Research › peer-review
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Conformational changes of the NADPH-dependent cytochrome P450 reductase in the course of electron transfer to cytochromes P450
Laursen, Tomas, Jensen, K. & Møller, Birger Lindberg, 2011, In: Biochimica et Biophysica Acta - Proteins and Proteomics. 1814, 1, p. 132-138 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Amphipol trapping of a functional CYP system
Laursen, Tomas, Naur, P. & Møller, Birger Lindberg, 2013, In: Biotechnology and Applied Biochemistry. 60, 1, p. 119-127 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Membrane anchoring facilitates colocalization of enzymes in plant cytochrome P450 redox systems
Laursen, Tomas, Lam, H. Y. M., Sorensen, K. K., Tian, P., Hansen, Cecilie Ida Cetti, Groves, J. T., Jensen, Knud Jørgen & Christensen, S. M., 2021, In: Communications Biology . 4, 9 p., 1057.Research output: Contribution to journal › Journal article › Research › peer-review
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Characterization of a dynamic metabolon producing the defense compound dhurrin in sorghum
Laursen, Tomas, Borch-Jensen, J., Baden, C. K., Bavishi, K., Torta, F., Martens, Helle Jakobe, Silvestro, D., Hatzakis, Nikos, Wenk, M. R., Dafforn, T. R., Olsen, C. E., Motawie, Mohammed Saddik, Hamberger, B. R., Møller, Birger Lindberg & Bassard, J. A., 2016, In: Science (New York, N.Y.). 354, 6314, p. 890-893 4 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Single molecule activity measurements of cytochrome P450 oxidoreductase reveal the existence of two discrete functional states
Laursen, Tomas, Singha, A., Rantzau, N., Tutkus, M., Borch-Jensen, J., Hedegård, Per, Stamou, Dimitrios, Møller, Birger Lindberg & Hatzakis, Nikos, 2014, In: ACS chemical biology. 9, 3, p. 630-634 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
Bifunctional glycosyltransferases catalyze both extension and termination of pectic galactan oligosaccharides
Laursen, Tomas, Stonebloom, S. H., Pidatala, V. R., Birdseye, D. S., Clausen, M. H., Mortimer, J. C. & Scheller, H. V., 2018, In: Plant Journal. 94, 2, p. 340-351 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Plasticity of specialized metabolism as mediated by dynamic metabolons
Laursen, Tomas, Møller, Birger Lindberg & Bassard, J. A., 2015, In: Trends in Plant Science. 20, 1, p. 20-32 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
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Exploiting photosynthesis-driven P450 activity to produce indican in tobacco chloroplasts
Mellor, Silas Busck, Behrendorff, J. B. Y. H., Ipsen, J. O., Crocoll, C., Laursen, Tomas, Gillam, E. M. J. & Pribil, Mathias, 2023, In: Frontiers in Plant Science. 13, 17 p., 1049177.Research output: Contribution to journal › Journal article › Research › peer-review
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Links of conformational sampling to functional plasticity and clinical phenotypes by single molecule studies
Moses, M. E., Thodberg, S., Bavishi, K., Eiersholt, S., Li, D., Stamou, Dimitrios, Møller, Birger Lindberg, Laursen, Tomas & Hatzakis, Nikos, 2016, In: Biophysical Society. Annual Meeting. Abstracts. 110, 3, p. 397A 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
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Metabolons and bio-condensates: The essence of plant plasticity and the key elements in development of green production systems
Møller, Birger Lindberg & Laursen, Tomas, 2021, Advances in Botanical Research. Academic Press, p. 185-223 (Advances in Botanical Research, Vol. 97).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
Controlling styrene maleic acid lipid particles through RAFT
Smith, A. A. A., Autzen, Henriette Elisabeth, Laursen, Tomas, Wu, V., Yen, M., Hall, A., Hansen, S. D., Cheng, Y. & Xu, T., 2017, In: Biomacromolecules. 18, 11, p. 3706-3713 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Monitoring shifts in the conformation equilibrium of the membrane protein cytochrome P450 reductase (POR) in nanodiscs
Wadsäter, M. H., Laursen, Tomas, Singha, A., Hatzakis, Nikos, Stamou, Dimitrios, Barker, R., Mortensen, Kell, Feidenhans'l, Robert Krarup, Møller, Birger Lindberg & Cardenas Gomez, M., 2012, In: Journal of Biological Chemistry. 287, 41, p. 34596-34603 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 16022160
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330
downloads
Dynamic metabolic solutions to the sessile life style of plants
Research output: Contribution to journal › Review › Research › peer-review
Published -
286
downloads
Application of nanodisc technology for direct electrochemical investigation of plant cytochrome P450s and their NADPH P450 oxidoreductase
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
192
downloads
Links of conformational sampling to functional plasticity and clinical phenotypes by single molecule studies
Research output: Contribution to journal › Conference abstract in journal › Research
Published