Kristian Erik Høpfner Frandsen

Kristian Erik Høpfner Frandsen

Assistant Professor


  1. 2013
  2. Published

    Binding of the N-terminal domain of the lactococcal bacteriophage TP901-1 CI repressor to its target DNA: a crystallography, small angle scattering, and nuclear magnetic resonance study

    Frandsen, Kristian Erik Høpfner, Rasmussen, K. K., Jensen, M. R., Hammer, K., Pedersen, M., Poulsen, Jens-Christian Navarro, Arleth, Lise & Lo Leggio, Leila, 2013, In: Biochemistry. 52, 39, p. 6892-6904 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2015
  4. Published

    Structural diversity of lytic polysaccharide monooxygenases

    Lo Leggio, Leila, Frandsen, Kristian Erik Høpfner, Poulsen, Jens-Christian Navarro, Tovborg, M., De Maria, L. & Johansen, K. S., 2015, Proceedings of "Mie Bioforum 2014 - Lignocellulose Degradation and Biorefinery". Sakka, K., Kimura, T., Tamaru, Y., Karita, S. & Sakka, M. (eds.). UNI Publishers Co., Ltd, p. 148-156 9 p.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  5. Published

    Structure and boosting activity of a starch-degrading lytic polysaccharide monooxygenase

    Lo Leggio, Leila, Simmons, T. J., Poulsen, Jens-Christian Navarro, Frandsen, Kristian Erik Høpfner, Hemsworth, G. R., Stringer, M. A., von Freiesleben, P., Tovborg, M., Johansen, Katja Salomon, De Maria, L., Harris, P. V., Soong, C., Dupree, P., Tryfona, T., Lenfant, N., Henrissat, B., Davies, G. J. & Walton, P. H., 2015, In: Nature Communications. 6, 9 p., 5961.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. 2016
  7. Published

    Lytic polysaccharide monooxygenases: a crystallographer's view on a new class of biomass-degrading enzymes

    Frandsen, Kristian Erik Høpfner & Lo Leggio, Leila, 2016, In: IUCrJ. 3, Part 6, p. 448-467 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    Structural and dynamics studies of a truncated variant of CI repressor from bacteriophage TP901-1

    Rasmussen, K. K., Frandsen, Kristian Erik Høpfner, Boeri Erba, E., Pedersen, M., Varming, A. K., Hammer, K., Kilstrup, M., Thulstrup, Peter Waaben, Blackledge, M., Jensen, M. R. & Lo Leggio, Leila, 2016, In: Scientific Reports. 6, 12 p., 29574.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    Structural characterization of Lytic Polysaccharide MonoOxygenases: Enzymatic interactions with lignocellulosic- and starch substrates

    Frandsen, Kristian Erik Høpfner, 2016, Department of Chemistry, Faculty of Science, University of Copenhagen.

    Research output: Book/ReportPh.D. thesisResearch

  10. Published

    The molecular basis of polysaccharide cleavage by lytic polysaccharide monooxygenases

    Frandsen, K. E. H., Simmons, T. J., Dupree, P., Poulsen, J-C. N., Hemsworth, G. R., Ciano, L., Johnston, E. M., Tovborg, M., Johansen, K. S., von Freiesleben, P., Marmuse, L., Fort, S., Cottaz, S., Driguez, H., Henrissat, B., Lenfant, N., Tuna, F., Baldansuren, A., Davies, G. J., Lo Leggio, L. & 1 others, Walton, P. H., 2016, In: Nature Chemical Biology. 12, 4, p. 298-303 6 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. 2017
  12. Published

    Learning from oligosaccharide soaks of crystals of an AA13 lytic polysaccharide monooxygenase: crystal packing, ligand binding and active-site disorder

    Frandsen, Kristian Erik Høpfner, Poulsen, Jens-Christian Navarro, Tovborg, M., Johansen, Katja Salomon & Lo Leggio, Leila, 2017, In: Acta crystallographica Section D: Structural biology . 73, p. 64-76 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Structural and electronic determinants of lytic polysaccharide monooxygenase reactivity on polysaccharide substrates

    Simmons, T. J., Frandsen, Kristian Erik Høpfner, Ciano, L., Tryfona, T., Lenfant, N., Poulsen, Jens-Christian Navarro, Wilson, L. F. L., Tandrup, T., Tovborg, M., Schnorr, K., Johansen, Katja Salomon, Henrissat, B., Walton, P. H., Lo Leggio, Leila & Dupree, P., 2017, In: Nature Communications. 8, 12 p., 1064.

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Unliganded and substrate bound structures of the cellooligosaccharide active lytic polysaccharide monooxygenase LsAA9A at low pH

    Frandsen, Kristian Erik Høpfner, Poulsen, Jens-Christian Navarro, Tandrup, T. & Lo Leggio, Leila, 2017, In: Carbohydrate Research. 448, p. 187-190 4 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

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