Kenneth Thermann Kongstad
Guest Researcher
Biopharmaceuticals
Jagtvej 162
2100 København Ø
Section for Plant Biochemistry
Thorvaldsensvej 40
1871 Frederiksberg C
- 2023
- Published
Polypharmacology-labeled molecular networking: An analytical technology workflow for accelerated identification of multiple bioactive constituents in complex extracts
Zhao, Yong, Gericke, Oliver, Li, T., Kjaerulff, Louise, Kongstad, Kenneth Thermann, Heskes, A. M., Møller, Birger Lindberg, Jørgensen, Flemming Steen, Venter, H., Coriani, S., Semple, S. J. & Stærk, Dan, 2023, In: Analytical Chemistry. 95, 9, p. 4381-4389 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Coupling microplate-based antibacterial assay with liquid chromatography for high-resolution growth inhibition profiling of crude extracts: Validation and proof-of-concept study with Staphylococcus aureus
Ardalani, H., Anam, S., Kromphardt, K. J. K., Stærk, Dan & Kongstad, Kenneth Thermann, 2021, In: Molecules. 26, 6, 12 p., 1550.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dual high-resolution α-glucosidase and PTP1B profiling combined with HPLC-PDA-HRMS-SPE-NMR analysis for the identification of potentially antidiabetic chromene meroterpenoids in Rhododendron capitatum
Liang, Chao, Kjaerulff, Louise, Hansen, Paul Robert, Kongstad, Kenneth Thermann & Stærk, Dan, 2021, In: Journal of Natural Products. 84, p. 2454-2467Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Effect of Roux-en-Y gastric bypass on the pharmacokinetic-pharmacodynamic relationships of liquid and controlled-release formulations of oxycodone
Ladebo, L., Abuhelwa, A. Y., Foster, D. J. R., Kroustrup, J. P., Pacyk, G. J., Kongstad, Kenneth Thermann, Drewes, A. M., Christrup, Lona Louring & Olesen, A. E., 2021, In: Basic and Clinical Pharmacology and Toxicology. 129, 3, p. 232-245Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Potential antidiabetic phytochemicals in plant roots: a review of in vivo studies
Ardalani, H., Hejazi Amiri, F., Hadipanah, A. & Kongstad, Kenneth Thermann, 2021, In: Journal of Diabetes and Metabolic Disorders. 20, p. 1837–1854Research output: Contribution to journal › Review › Research › peer-review
- Published
Reversal of ABCG2/BCRP-mediated multidrug resistance by 5,3’,5’-trihydroxy-3,6,7,4’-tetramethoxyflavone isolated from the Australian desert plant Eremophila galeata Chinnock
Petersen, M. J., Lund, X. L., Semple, S. J., Buirchell, B., Franzyk, Henrik, Gajhede, Michael, Kongstad, Kenneth Thermann, Stenvang, Jan & Stærk, Dan, 2021, In: Biomolecules. 11, 10, 19 p., 1534.Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
Structure elucidation of prenyl- and geranyl substituted coumarins in Gerbera piloselloides by NMR spectroscopy, electronic circular dichroism calculations, and single crystal X-ray crystallography
Li, T., Ma, X., Fedotov, D., Kjaerulff, Louise, Frydenvang, Karla Andrea, Coriani, S., Hansen, Paul Robert, Kongstad, Kenneth Thermann & Stærk, Dan, 8 Apr 2020, In: Molecules. 25, 25 p., 1706.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antidiabetic xanthones with α-glucosidase inhibitory activities from an endophytic Penicillium canescens
Malik, A., Ardalani, H., Anam, S., McNair, Laura M., Kromphardt, K. J. K., Frandsen, R. J. N., Franzyk, Henrik, Stærk, Dan & Kongstad, Kenneth Thermann, 2020, In: Fitoterapia. 142, 8 p., 104522.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Population pharmacokinetic-pharmacodynamic modelling of liquid and controlled-release formulations of oxycodone in healthy volunteers
Ladebo, L., Foster, D. J. R., Abuhelwa, A. Y., Upton, R. N., Kongstad, Kenneth Thermann, Drewes, A. M., Christrup, Lona Louring & Olesen, A. E., 2020, In: Basic & Clinical Pharmacology & Toxicology. 126, 3, p. 263-276Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Potential of Myrtus communis Linn. as a bifunctional food: Dual high-resolution PTP1B and α-glucosidase inhibition profiling combined with HPLC-HRMS and NMR for identification of antidiabetic triterpenoids and phloroglucinol derivatives
Liang, Chao, Stærk, Dan & Kongstad, Kenneth Thermann, 2020, In: Journal of Functional Foods. 64, 10 p., 103623.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Five-membered N-heterocyclic Scaffolds as Novel Amino Bioisosteres at gamma-Aminobutyric Acid (GABA) Type A Receptors and GABA Transporters
Giraudo, A., Krall, J., Bavo, Francesco, Nielsen, Birgitte, Kongstad, Kenneth Thermann, Rolando, B., De Blasio, R., Gloriam, David E., Löffler, R., Thiesen, L., Harpsøe, Kasper, Frydenvang, Karla Andrea, Boschi, D., Wellendorph, Petrine, Lolli, M. L., Jensen, Anders A. & Frølund, Bente, 27 Jun 2019, In: Journal of Medicinal Chemistry. 62, 12, p. 5797-5809Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Discovery of 2-(Imidazo[1,2-b]pyridazin-2-yl)acetic Acid as a New Class of Ligands Selective for the γ-Hydroxybutyric Acid (GHB) High-Affinity Binding Sites
Krall, J., Bavo, Francesco, Falk-Petersen, C. B., Jensen, C. H., Nielsen, J. O., Tian, Yongsong, Anglani, V., Kongstad, Kenneth Thermann, Petersen, Louise Piilgaard, Nielsen, Birgitte, Gloriam, David E., Kehler, J., Jensen, Anders A., Harpsøe, Kasper, Wellendorph, Petrine & Frølund, Bente, 14 Mar 2019, In: Journal of Medicinal Chemistry. 62, 5, p. 2798-2813Research output: Contribution to journal › Journal article › Research › peer-review
- Published
2(5H)-Furanone sesquiterpenes from Eremophila bignoniiflora: High-resolution inhibition profiling and PTP1B inhibitory activity
Zhao, Yong, Kjaerulff, Louise, Kongstad, Kenneth Thermann, Heskes, A. M., Møller, Birger Lindberg & Stærk, Dan, 2019, In: Phytochemistry. 166, p. 1-8 112054.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
19F-substituted amino acids as an alternative to fluorophore labels: monitoring of degradation and cellular uptake of analogues of penetratin by 19F NMR
Christensen, M. V., Kongstad, Kenneth Thermann, Sondergaard, T. E., Stærk, Dan, Nielsen, Hanne Mørck, Franzyk, Henrik & Wimmer, R., 2019, In: Journal of Biomolecular N M R. 73, p. 167-182Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Antidiabetic constituents of Dendrobium officinale as determined by high-resolution profiling of radical scavenging and α-glucosidase and α-amylase inhibition combined with HPLC-PDA-HRMS-SPE-NMR analysis.
Chu, C., Li, T., Pedersen, H. A., Kongstad, Kenneth Thermann, Yan, J. & Stærk, Dan, 2019, In: Phytochemistry Letters. 31, p. 47-52Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combined magnetic ligand fishing and high-resolution inhibition profiling for identification of α-glucosidase inhibitory ligands: A new screening approach based on complementary inhibition and affinity profiles.
Wubshet, S. G., Liu, B., Kongstad, Kenneth Thermann, Böcker, U., Petersen, M. J., Li, T., Wang, J. & Stærk, Dan, 2019, In: Talanta. 200, p. 279-287Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Developing New 4-PIOL and 4-PHP Analogues for Photoinactivation of γ-Aminobutyric Acid Type A Receptors
Mortensen, M., Krall, J., Kongstad, Kenneth Thermann, Brygger, B. M., Lenzi, O., Francotte, P., Sørensen, T. E., Nielsen, Birgitte, Jensen, Anders A., Smart, T. G. & Frølund, Bente, 2019, In: ACS Chemical Neuroscience. 10, 11, p. 4669-4684Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-dose naloxone, an experimental tool uncovering latent sensitisation: pharmacokinetics in humans.
Papathanasiou, T., Springborg, A., Kongstad, Kenneth Thermann, Stærk, Dan, Møller, Kirsten, Taylor, B. K., Lund, Trine Meldgaard & Werner, M. U., 2019, In: British Journal of Anaesthesia. 123, 2, p. e204-e214Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of α-glucosidase inhibitors in Machilus litseifolia by combined use of high-resolution α-glucosidase inhibition profiling and HPLC-PDA-HRMS-SPE-NMR
Li, T., Kongstad, Kenneth Thermann & Stærk, Dan, 2019, In: Journal of Natural Products. 82, p. 249-258Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Microwave-assisted solid-phase synthesis of antisense acpP peptide nucleic acid-peptide conjugates active against colistin- and tigecycline-resistant E. coli and K. pneumoniae
Hansen, A. M., Bonke, G., Hogendorf, W. F. J., Björkling, Fredrik, Nielsen, J., Kongstad, Kenneth Thermann, Zabicka, D., Tomczak, M., Urbas, M., Nielsen, Peter E. & Franzyk, Henrik, 2019, In: European Journal of Medicinal Chemistry. 168, p. 134-145 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Simultaneous quantification of high-dose naloxone and naloxone-3-β-D-glucuronide in human plasma by UHPLC-MS/MS
Kongstad, Kenneth Thermann, Papathanasiou, T., Springborg, A., Lund, Trine Meldgaard, Werner, M. U. & Stærk, Dan, 2019, In: Bioanalysis. 11, 03, p. 165-173Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Unraveling the complexity of complex mixtures by combining high-resolution pharmacological, analytical and spectroscopic techniques: Antidiabetic constituents in Chinese medicinal plants
Zhao, Yong, Kongstad, Kenneth Thermann, Liu, Y., He, C. & Stærk, Dan, 2019, In: Faraday Discussions. 218, p. 202-218Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
4-Hydroxy-1,2,3-triazole moiety as bioisostere of the carboxylic acid function: a novel scaffold to probe the orthosteric gamma-aminobutyric acid receptor binding site
Alessandro, G., Krall, J., Nielsen, Birgitte, Sørensen, T. E., Kongstad, Kenneth Thermann, Barbara, R., Donatella, B., Frølund, Bente & Lolli, M. L., 5 Oct 2018, In: European Journal of Medicinal Chemistry. 158, p. 311-321 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Brazilian insulin plant as a bifunctional food: Dual high-resolution PTP1B and α-glucosidase inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of antidiabetic compounds in Myrcia rubella Cambess
Lima, R. D. C. L., Kato, L., Kongstad, Kenneth Thermann & Stærk, Dan, 2018, In: Journal of Functional Foods. 45, p. 444-451Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Heterologous production of the widely used natural food colorant carminic acid in Aspergillus nidulans
Frandsen, R. J. N., Khorsand-Jamal, P., Kongstad, Kenneth Thermann, Nafisi, M., Kannangara, R. M., Stærk, Dan, Okkels, F. T., Binderup, K., Madsen, B., Møller, Birger Lindberg, Thrane, U. & Mortensen, U. H., 2018, In: Scientific Reports. 8, p. 1-10 10 p., 12853.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-resolution PTP1B inhibition profiling combined with HPLC-HRMS-SPE-NMR for identification of PTP1B inhibitors from Miconia albicans
Lima, R. D. C. L., Kongstad, Kenneth Thermann, Kato, L., José das Silva, M., Franzyk, Henrik & Stærk, Dan, 2018, In: Molecules. 23, 7, 13 p., 1755.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
On the biosynthetic origin of carminic acid
Rasmussen, S. A., Kongstad, Kenneth Thermann, Khorsand-Jamal, P., Kannangara, R. M., Nafisi, M., Van Dam, A., Bennedsen, M., Madsen, B., Okkels, F. T., Gotfredsen, C. H., Stærk, Dan, Thrane, U., Mortensen, U. H., Larsen, T. O. & Frandsen, R. J. N., 2018, In: Insect Biochemistry and Molecular Biology. 96, p. 51-61 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Quadruple high-resolution α-glucosidase/α-amylase/PTP1B/radical scavenging profiling combined with high-performance liquid chromatography – high-resolution mass spectrometry – solid-phase extraction – nuclear magnetic resonance spectroscopy for identification of antidiabetic constituents in crude root bark of Morus alba L.
Zhao, Yong, Kongstad, Kenneth Thermann, Jäger, A. K., Nielsen, J. & Stærk, Dan, 2018, In: Journal of Chromatography A. 1556, p. 55-63Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Recreational drug use at a major music festival: trend analysis of anonymised pooled urine
Hoegberg, L., Christiansen, C., Søe, J. L., Telving, R., Andreasen, M. F., Stærk, Dan, Christrup, Lona Louring & Kongstad, Kenneth Thermann, 2018, In: Clinical Toxicology. 56, p. 245-255 1360496.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Advancing HPLC-PDA-HRMS-SPE-NMR analysis of coumarins in Coleonema album by use of orthogonal reversed-phase C18 and pentafluorophenyl separations
Lima, R. D. C. L., Gramsbergen, S., Van Staden, J., Jäger, A. K., Kongstad, Kenneth Thermann & Stærk, Dan, 2017, In: Journal of Natural Products. 80, 4, p. 1020-1027Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of a membrane-bound C-glucosyltransferase responsible for carminic acid biosynthesis in Dactylopius coccus Costa
Kannangara, R. M., Siukstaite, L., Borch-Jensen, J., Madsen, B., Kongstad, Kenneth Thermann, Stærk, Dan, Bennedsen, M., Okkels, F. T., Rasmussen, S. A., Larsen, T. O., Frandsen, R. J. N. & Møller, Birger Lindberg, 2017, In: Nature Communications. 8, 12 p., 1987.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Characterization of antileishmanial compounds from Lawsonia inermis leaves using semi-high resolution antileishmanial profiling combined with HPLC-HRMS-SPE-NMR
Iqbal, K., Iqbal, J., Stærk, Dan & Kongstad, Kenneth Thermann, 2017, In: Frontiers in Pharmacology. 8, 7 p., 337.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Molecular Hybridization of Potent and Selective γ-Hydroxybutyric Acid (GHB) Ligands: Design, Synthesis, Binding Studies, and Molecular Modeling of Novel 3-Hydroxycyclopent-1-enecarboxylic Acid (HOCPCA) and trans-γ-Hydroxycrotonic Acid (T-HCA) Analogs
Krall, J., Jensen, C. H., Bavo, F., Falk-Petersen, C. B., Haugaard, A. S., Vogensen, S. B., Tian, Y., Nittegaard-Nielsen, M., Sigurdardóttir, S. B., Kehler, J., Kongstad, Kenneth Thermann, Gloriam, David E., Clausen, Rasmus Prætorius, Harpsøe, Kasper, Wellendorph, Petrine & Frølund, Bente, 2017, In: Journal of Medicinal Chemistry. 60, 21, p. 9022-9039 18 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Potential of Polygonum cuspidatum root as an antidiabetic food: Dual high-resolution α-glucosidase and PTP1B inhibition profiling combined with HPLC-HRMS and NMR for identification of antidiabetic constituents
Zhao, Yong, Chen, M. X., Kongstad, Kenneth Thermann, Jäger, A. K. & Stærk, Dan, 2017, In: Journal of Agricultural and Food Chemistry. 65, p. 4421-4427Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Synthesis of C-glucosylated octaketide anthraquinones in Nicotiana benthamiana using a multispecies-based biosynthetic pathway
Andersen-Ranberg, Johan, Kongstad, Kenneth Thermann, Nafisi, M., Stærk, Dan, Okkels, F. T., Mortensen, U. H., Møller, Birger Lindberg, Frandsen, R. J. N. & Kannangara, R. M., 2017, In: ChemBioChem. 18, 19, p. 1893-1897 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Accelerating drug lead discovery from nature by high-resolution bioactivity profiling combined with HPLC-HRMS-SPE-NMR
Kongstad, Kenneth Thermann, Nyberg, N. T., Wubshet, S. G. & Stærk, Dan, Dec 2016, In: Planta Medica. 81, S 01Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
HPLC-HRMS-SPE-NMR combined with high resolution in vitro screening for natural fungicides
Kongstad, Kenneth Thermann, Wubshet, S. G., Kjellerup, L., Winther, A. & Stærk, Dan, Dec 2016, In: Planta Medica. 82, S 01Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
HPLC-HRMS-SPE-NMR for accelerated identification of compounds in complex plant extracts: New coumarine derivatives from Coleonema album (Thunb.) Bartl. & Wendl
de Cássia Lemos Lima, R., Gramsbergen, S. M., Van Staden, J., Jäger, A. K., Kongstad, Kenneth Thermann & Stærk, Dan, Dec 2016, In: Planta Medica. 82, S 01Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Ligand-fishing and bioactivity-correlated metabolomics for accelerated discovery of antidiabetic drug leads
Nyberg, N. T., Wubshet, S. G., Kongstad, Kenneth Thermann & Stærk, Dan, Dec 2016, In: Planta Medica. 82, S 01Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
The α-glucosidase and PTP1B inhibitory effect of 45 medicinal plants extracts
Liu, B., Kongstad, Kenneth Thermann, Jäger, A. K. & Stærk, Dan, Dec 2016, In: Planta Medica. 81, S 01, p. 1 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
Characterization of midazolam metabolism in locusts: The role of CYP3A4-like enzyme in the formation of 1'-OH and 4-OH midazolam
Olsen, L. R., Gabel-Jensen, C., Wubshet, S. G., Kongstad, Kenneth Thermann, Janfelt, Christian, Badolo, L. & Hansen, S. H., 2016, In: Xenobiotica. 46, 2, p. 99–107 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Edible seaweed as future functional food: Identification of α-glucosidase inhibitors by combined use of high-resolution α-glucosidase inhibition profiling and HPLC-HRMS-SPE-NMR
Liu, B., Kongstad, Kenneth Thermann, Wiese, S., Jäger, A. K. & Stærk, Dan, 2016, In: Food Chemistry. 203, p. 16-22 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Expanding the landscape of diterpene structural diversity by stereochemically controlled combinatorial biosynthesis
Andersen-Ranberg, Johan, Kongstad, Kenneth Thermann, Nielsen, M. T., Bjerg Jensen, N., Pateraki, Irini, Bach, S. S., Hamberger, B., Zerbe, P., Stærk, Dan, Bohlmann, J., Møller, Birger Lindberg & Hamberger, B. R., 2016, In: Angewandte Chemie International Edition. 55, 6, p. 2142-2146 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
- Published
High-resolution PTP1B inhibition profiling combined with high-performance liquid chromatography - high-resolution mass spectrometry - solid-phase extraction - nuclear magnetic resonance spectroscopy: Proof-of-concept and antidiabetic constituents in crude extract of Eremophila lucida
Tahtah, Y., Wubshet, S. G., Kongstad, Kenneth Thermann, Heskes, A. M., Pateraki, Irini, Møller, Birger Lindberg, Jäger, A. & Stærk, Dan, 2016, In: Fitoterapia. 110, p. 52-58 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of PTP1B and α-glucosidase inhibitory serrulatanes from Eremophila spp. by combined use of dual high-resolution PTP1B and α-glucosidase inhibition profiling and HPLC-HRMS-SPE-NMR
Wubshet, S. G., Tahtah, Y., Heskes, A. M., Kongstad, Kenneth Thermann, Pateraki, Irini, Hamberger, B. R., Møller, Birger Lindberg & Stærk, Dan, 2016, In: Journal of Natural Products. 79, 4, p. 1063-1072 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
High-resolution α-glucosidase and radical scavenging profiling combined with HPLC-HRMS-SPE-NMR for identification of bioactive constituents in crude extract of Pueraria lobata
Liu, B., Kongstad, Kenneth Thermann, Nyberg, N. T., Sun, Q., Jager, A. K. & Stærk, Dan, Nov 2015, In: Planta Medica. 81, 16, p. 1437-1437Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- Published
High-resolution α-glucosidase and radical scavenging profiling combined with HPLC-HRMS-SPE-NMR for identification of bioactive constituents in crude extract of Pueraria lobata
Liu, B., Kongstad, Kenneth Thermann, Nyberg, N., Qinglei, S., Jäger, A. K. & Stærk, Dan, 26 Aug 2015.Research output: Contribution to conference › Poster › Research
- Published
Flipped Learning in Organic Chemistry for Life Sciences – Experiences and Considerations
Kongstad, Kenneth Thermann, 24 Aug 2015, Pedagogical Projects 2014. Vol. 7. p. 125-147 (Improving University Science Teaching and Learning; No. 1-2, Vol. 7).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Education
- Published
Fungal plasma membrane H+-ATPase inhibitory activity of o-hydroxybenzylated flavanones and chalcones from Uvaria chamae P. Beauv
Kongstad, Kenneth Thermann, Wubshet, S. G., Kjellerup, L., winther, A. L. & Stærk, Dan, 20 Jun 2015, In: Fitoterapia. 105, p. 102-106 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Dual High-Resolution α-Glucosidase and Radical Scavenging Profiling Combined with HPLC-HRMS-SPE-NMR for Identification of Minor and Major Constituents Directly from the Crude Extract of Pueraria lobata
Liu, B., Kongstad, Kenneth Thermann, Qinglei, S., Nyberg, N., Jäger, A. & Stærk, Dan, 13 Feb 2015, In: Journal of Natural Products. 78, 2, p. 294–300 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Combined use of high-resolution α-glucosidase inhibition profiling and HPLC-HRMS-SPE-NMR for investigation of antidiabetic principles in crude plant extracts
Kongstad, Kenneth Thermann, Özdemir, C., Barzak, A., Wubshet, S. G. & Stærk, Dan, 5 Feb 2015, In: Journal of Agricultural and Food Chemistry. 63, 8, p. 2257-2263 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-resolution α-glucosidase and radical scavenging profiling combined with HPLC-HRMS-SPE-NMR for identification of bioactive constituents in crude extract of Pueraria lobata
Liu, B., Kongstad, Kenneth Thermann, Nyberg, N., Qinglei, S., Jäger, A. & Stærk, Dan, 2015.Research output: Contribution to conference › Poster › Research
- Published
Identification of Fungal Plasma Membrane H+-ATPase Inhibitors in Lecaniodiscus cupanioides by HPLC-HRMS-SPE-NMR
Straadt, I. K., Kongstad, Kenneth Thermann & Stærk, Dan, 2015.Research output: Contribution to conference › Poster › Research
- Published
Triple aldose reductase/α-glucosidase/radical scavenging high-resolution profiling combined with high-performance liquid chromatography – high-resolution mass spectrometry – solid-phase extraction – nuclear magnetic resonance spectroscopy for identification of antidiabetic constituents in crude extract of Radix Scutellariae
Tahtah, Y., Kongstad, Kenneth Thermann, Wubshet, S. G., Nyberg, N., Jønsson, L. H., Jäger, A. K., Qinglei, S. & Stærk, Dan, 2015, In: Journal of Chromatography A. 1408, p. 125-132 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
- Published
Positive allosteric modulation of the GHB high-affinity binding site by the GABAA receptor modulator monastrol and the flavonoid catechin
Eghorn, L. F., Høstgaard-Jensen, K., Kongstad, Kenneth Thermann, Bay, T., Higgins, D., Frølund, Bente & Wellendorph, Petrine, 5 Oct 2014, In: European Journal of Pharmacology. 740, p. 570-577 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
5-(Piperidin-4-yl)-3-Hydroxypyrazole: A Novel Scaffold for Probing the Orthosteric γ-Aminobutyric Acid Type A Receptor Binding Site
Krall, J., Kongstad, Kenneth Thermann, Nielsen, Birgitte, Sørensen, T. E., Balle, T., Jensen, Anders A. & Frølund, Bente, 2014, In: ChemMedChem. 9, 11, p. 2475-2485 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-resolution screening combined with HPLC–HRMS–SPE–NMR for identification of fungal plasma membrane H+-ATPase inhibitors from plants
Kongstad, Kenneth Thermann, Wubshet, S. G., Johannesen, A., Kjellerup, L., winther, A. L., Jäger, A. & Stærk, Dan, 2014, In: Journal of Agricultural and Food Chemistry. 62, 24, p. 5595-5602 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
High-resolution α-amylase assay combined with high-performance liquid chromatography−solid-phase extraction−nuclear magnetic resonance spectroscopy for expedited identification of α-amylase inhibitors – proof of concept and α-amylase inhibitor in cinnamon.
Okutan, L., Kongstad, Kenneth Thermann, Jäger, A. & Stærk, Dan, 2014, In: Journal of Agricultural and Food Chemistry. 62, 47, p. 11465-11471 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification of Fungal H+-ATPase Inhibitors by Microfractionation and HPLC-HRMS-SPE-NMR
Wubshet, S. G., Kongstad, Kenneth Thermann, Johannesen, A., Nyberg, N., Jäger, A., Kjellerup, L., Vinther, A. & Stærk, Dan, 2014.Research output: Contribution to conference › Poster › Research
- 2013
- Published
Advanced hyphenated NMR techniques for natural product research and other pharmaceutical applications
Kongstad, Kenneth Thermann, 2013, Cph.: Faculty of Health and Medical Sciences, University of Copenhagen.Research output: Book/Report › Ph.D. thesis › Research
- Published
HPLC-NMR revisited: Using time-slice HPLC-SPE-NMR with database assisted dereplication
Kongstad, Kenneth Thermann, Wubshet, S. G. & Nyberg, N., 2013, In: Analytical Chemistry. 85, 6, p. 3183-3189Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Some transformations of tacrolimus, an immunosuppressive drug
Skytte, D. M., Jaroszewski, J. W., Kongstad, Kenneth Thermann, Hansen, S. H., Hansen, L., G. Nielsen, P. & Frydenvang, Karla Andrea, 2013, In: European Journal of Pharmaceutical Sciences. 48, 3, p. 514-522 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
- Published
Alkaloid analysis by high-performance liquid chromatography-solid phase extraction-nuclear magnetic resonance: New strategies going beyond the standard
Kongstad, Kenneth Thermann, Ebild, S. J., Christensen, Søren Brøgger, Godejohann, M. & Jaroszewski, J. W., 28 Dec 2012, In: Journal of Chromatography A. 1270, p. 171-177 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
5-(Piperidine-4-yl)-3-hydroxypyrazole: a novel scaffold forprobing the orthosteric GABAA receptor binding site
Krall, J., Kongstad, Kenneth Thermann, Balle, T., Nielsen, Birgitte, Jensen, A. A. & Frølund, Bente, 2 Sep 2012.Research output: Contribution to conference › Poster › Research
- Published
Direct 13C NMR Detection in HPLC Hyphenation Mode: Analysis of Ganoderma lucidum Terpenoids
Wubshet, S. G., Kongstad, Kenneth Thermann, Nyberg, N. & Jaroszewski, J. W., 19 Apr 2012, In: Journal of Natural Products. 75, 5, p. 876-882 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2011
- Published
From retrospective assessment to prospective decisions in natural product isolation: HPLC-SPE-NMR analysis of Carthamus oxyacantha
Kongstad, Kenneth Thermann, Wubshet, S. G., Nyberg, N. T. & Jaroszewski, J. W., 28 Nov 2011, In: Journal of Natural Products. 74, 11, p. 2454-2461Research output: Contribution to journal › Journal article › Research › peer-review
- Published
From Retrospective Assessment to Prospective Decisions in Natural Product Isolation
Kongstad, Kenneth Thermann, 2011.Research output: Contribution to conference › Poster › Research
- Published
Hyphenated NMR techniques
Kesting, J. R., Kongstad, Kenneth Thermann & Jaroszewski, J. W., 2011, Biomolecular NMR spectroscopy. Dingley, A. J. & Pascal, S. M. (eds.). Amsterdam: IOS Press, Vol. 3. p. 413-434 (Advances in Biomedical Spectroscopy, Vol. 3).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- Published
NMR spectra database for on-flight identification of HPLC-SPE-NMR data
Kongstad, Kenneth Thermann, 2011.Research output: Contribution to conference › Poster › Research
- 2010
- Published
NMR spectra database for on-flight identification of HPLC-SPE-NMR data: proof of concept
Kongstad, Kenneth Thermann, 2010.Research output: Contribution to conference › Poster › Research
ID: 13868131
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2398
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Identification of Fungal H+-ATPase Inhibitors by Microfractionation and HPLC-HRMS-SPE-NMR
Research output: Contribution to conference › Poster › Research
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1639
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5-(Piperidine-4-yl)-3-hydroxypyrazole: a novel scaffold forprobing the orthosteric GABAA receptor binding site
Research output: Contribution to conference › Poster › Research
Published -
1205
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NMR spectra database for on-flight identification of HPLC-SPE-NMR data: proof of concept
Research output: Contribution to conference › Poster › Research
Published