Fernando Geu-Flores
Associate Professor
- 2005
- Published
Engineering the glucosinolate pathway into potato
Geu-Flores, Fernando, Halkier, Barbara Ann, Ghislain, M. & Cosio, E., 2005. 1 p.Research output: Contribution to conference › Poster › Research
- 2006
- Published
Cytochromes P450 in the biosynthesis of glucosinolates and indole alkaloids
Nafisi, M., Sønderby, I. E., Hansen, B. G., Geu-Flores, Fernando, Nour-Eldin, Hussam Hassan, Nørholm, M. H. H., Jensen, N. B., Li, J. & Halkier, Barbara Ann, 2006, In: Phytochemistry Reviews. 5, 2-3, p. 331-346 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Engineering the glucosinolate pathway into potato
Geu-Flores, Fernando, Halkier, Barbara Ann, Ghislain, M. & Cosio, E., 2006. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
Engineering the glucosinolate pathway into yeast
Geu-Flores, Fernando, Nielsen, M. T. & Halkier, Barbara Ann, 2006. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
Engineering the glucosinolate pathway into yeast
Geu-Flores, Fernando, Nielsen, M. T. & Halkier, Barbara Ann, 2006. 1 p.Research output: Contribution to conference › Poster › Research
- Published
Engineering the glucosinolate pathway into yeast
Geu-Flores, Fernando, Nielsen, M. T. & Halkier, Barbara Ann, 2006. 1 p.Research output: Contribution to conference › Poster › Research
- Published
Heterologous expression of the glucosinolate pathway
Geu-Flores, Fernando, Nielsen, M. T., Ghislain, M., Cosio, E. & Halkier, Barbara Ann, 2006. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research
- 2007
- Published
Engineering the glucosinolate pathway into potato
Geu-Flores, Fernando, Halkier, Barbara Ann & Ghislan, M., 2007. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
USER fusion: a rapid and efficient method for simultaneous fusion and cloning of multiple PCR products
Geu-Flores, Fernando, Nour-Eldin, Hussam Hassan, Nielsen, M. T. & Halkier, Barbara Ann, 2007, In: Nucleic Acids Research. 35, 7, 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Uracil-excision based cloning and DNA-fusion technology - an ideal platform for both high-troughput and single-gene plant molecular biology
Nørholm, M. H. H., Nour-Eldin, Hussam Hassan, Hansen, B. G., Jensen, J. K., Geu-Flores, Fernando, Nielsen, M. T. & Halkier, Barbara Ann, 2007. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
Uracil-excision based cloning and DNA-fusion technology – an ideal platform for both high-throughput and single-gene plant molecular biology
Nørholm, M. H. H., Nour-Eldin, Hussam Hassan, Hansen, B. G., Jensen, J. K., Geu-Flores, Fernando, Nielsen, M. T. & Halkier, Barbara Ann, 2007. 1 p.Research output: Contribution to conference › Poster › Research
- Published
Uracil-excision based cloning and DNA-fusion technology – an ideal platform for both high-throughput and single-gene plant molecular biology
Geu-Flores, Fernando, Nørholm, M. H. H., Nour-Eldin, Hussam Hassan, Hansen, B. G., Jensen, J. K., Nielsen, M. T. & Halkier, Barbara Ann, 2007. 1 p.Research output: Contribution to conference › Poster › Research
- 2008
- Published
Engineering glucosinolates into non-crucifers
Geu-Flores, Fernando, 2008, Department of Plant Biology, University of Copenhagen.Research output: Book/Report › Ph.D. thesis › Research
- 2009
- Published
- Published
A toolkit for engineering multi-enzyme pathways into higher plants
Geu-Flores, Fernando, Nielsen, M. T., Møldrup, M. E., Olsen, C. E., Motawie, Mohammed Saddik & Halkier, Barbara Ann, 2009. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
Engineering benzylglucosinolate into tobacco
Mikkelsen, M. D., Geu-Flores, Fernando, Nielsen, M. T., Nafisi, M., Møldrup, M. E., Olsen, C. E., Motawie, Mohammed Saddik & Halkier, Barbara Ann, 2009. 1 p.Research output: Contribution to conference › Conference abstract for conference › Research
- Published
Engineering of benzyl glucosinolate identifies a critical γ-glutamyl peptidase
Geu-Flores, Fernando, Nielsen, M. T., Nafisi, M., Møldrup, M. E., Olsen, C. E., Motawie, Mohammed Saddik & Halkier, Barbara Ann, 2009. 1 p.Research output: Contribution to conference › Poster › Research
- Published
Glucosinolate engineering identifies a missing biosynthetic enzyme
Geu-Flores, Fernando, Nielsen, M. T., Nafisi, M., Møldrup, M. E., Motawie, Mohammed Saddik, Olsen, C. E. & Halkier, Barbara Ann, 2009. 1 p.Research output: Contribution to conference › Poster › Research
- Published
Glucosinolate engineering identifies a ¿-glutamyl peptidase
Geu-Flores, Fernando, Nielsen, M. T., Nafisi, M., Møldrup, M. E., Olsen, C. E., Motawie, Mohammed Saddik & Halkier, Barbara Ann, 2009, In: Nature Chemical Biology. 5, p. 575-577 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Towards engineering glucosinolates into non-cruciferous plants
Geu-Flores, Fernando, Olsen, C. E. & Halkier, Barbara Ann, 2009, In: Planta. 229, 2, p. 261-270 10 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2010
- Published
Biosynthesis of glucosinolates - gene discovery and beyond
Sønderby, I. E., Geu-Flores, Fernando & Halkier, Barbara Ann, 2010, In: Trends in Plant Science. 15, 5, p. 283-290 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
USER cloning and USER fusion: the ideal cloning techniques for small and big laboratories
Nour-Eldin, Hussam Hassan, Geu-Flores, Fernando & Halkier, Barbara Ann, 2010, Plant secondary metabolism engineering: methods and applications. Fett-Neto, A. G. (ed.). Springer Science+Business Media, Vol. 643. p. 185-200 16 p. (Methods in Molecular Biology, Vol. 643).Research output: Chapter in Book/Report/Conference proceeding › Book chapter › Research › peer-review
- 2011
- Published
Cytosolic γ-glutamyl peptidases process glutathione conjugates in the biosynthesis of glucosinolates and camalexin in Arabidopsis
Geu-Flores, Fernando, Møldrup, M. E., Böttcher, C., Olsen, C. E., Scheel, D. & Halkier, Barbara Ann, 2011, In: Plant Cell. 23, 6, p. 2456-2469 14 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Modulation of sulfur metabolism enables efficient glucosinolate engineering
Møldrup, M. E., Geu-Flores, Fernando, Olsen, C. E. & Halkier, Barbara Ann, 2011, In: B M C Biotechnology. 11, 12, 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2012
An alternative route to cyclic terpenes by reductive cyclization in iridoid biosynthesis
Geu-Flores, Fernando, Sherden, N. H., Courdavault, V., Burlat, V., Glenn, W. S., Wu, C., Nims, E., Cui, Y. & O'Connor, S. E., 2012, In: Nature. 492, 7427, p. 138-42 5 p.Research output: Contribution to journal › Letter › Research › peer-review
- Published
Engineering of benzylglucosinolate in tobacco provides proof-of-concept for dead-end trap crops genetically modified to attract Plutella xylostella (diamondback moth)
Møldrup, M. E., Geu-Flores, Fernando, de Vos, M., Olsen, C. E., Sun, J., Jander, G. & Halkier, Barbara Ann, 2012, In: Plant Biotechnology Journal. 10, 4, p. 435-442 8 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2013
- Published
De novo genetic engineering of the camalexin biosynthetic pathway
Møldrup, M. E., Salomonsen, B., Geu-Flores, Fernando, Olsen, C. E. & Halkier, Barbara Ann, 2013, In: Journal of Biotechnology. 167, 3, p. 296-301 6 p.Research output: Contribution to journal › Journal article › Research › peer-review
A pair of tabersonine 16-hydroxylases initiates the synthesis of vindoline in an organ-dependent manner in Catharanthus roseus
Besseau, S., Kellner, F., Lanoue, A., Thamm, A. M. K., Salim, V., Schneider, B., Geu Flores, F., Höfer, R., Guirimand, G., Guihur, A., Oudin, A., Glevarec, G., Foureau, E., Papon, N., Clastre, M., Giglioli-Guivarc'h, N., St-Pierre, B., Werck-Reichhart, D., Burlat, V., De Luca, V. & 2 others, , 2013, In: Plant Physiology. 163, 4, p. 1792-803 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2014
Conversion of substrate analogs suggests a Michael cyclization in iridoid biosynthesis
Lindner, S., Geu-Flores, Fernando, Bräse, S., Sherden, N. H. & O'Connor, S. E., 2014, In: Chemistry & Biology. 21, 11, p. 1452-1456 5 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2015
- Published
Discovery of a P450-catalyzed step in vindoline biosynthesis: a link between the aspidosperma and eburnamine alkaloids
Kellner, F., Geu-Flores, Fernando, Sherden, N. H., Brown, S., Foureau, E., Courdavault, V. & O'Connor, S. E., 2015, In: Chemical Communications. 51, 36, p. 7626-7628 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2016
- Published
Glucosinolate diversity within a phylogenetic framework of the tribe Cardamineae (Brassicaceae) unraveled with HPLC-MS/MS and NMR-based analytical distinction of 70 desulfoglucosinolates
Olsen, C. E., Huang, X., Hansen, Cecilie Ida Cetti, Cipollini, D., Ørgaard, Marian, Matthes, A., Geu-Flores, Fernando, Koch, M. A. & Agerbirk, Niels, 2016, In: Phytochemistry. 132, p. 33-56 24 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Identification and characterization of the iridoid synthase involved in oleuropein biosynthesis in olive (Olea europaea) fruits
Alagna, F., Geu-Flores, Fernando, Kries, H., Panara, F., Baldoni, L., O'Connor, S. E. & Osbourn, A., 2016, In: Journal of Biological Chemistry. 291, 11, p. 5542-5554 13 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural determinants of reductive terpene cyclization in iridoid biosynthesis
Kries, H., Caputi, L., Stevenson, C. E. M., Kamileen, M. O., Sherden, N. H., Geu-Flores, Fernando, Lawson, D. M. & O'Connor, S. E., 2016, In: Nature Chemical Biology. 12, 1, p. 6-8 3 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcriptome sequencing in narrow-leafed lupin (Lupinus angustifolius): combining short- and long-read sequencing platforms
Yang, T., Nagy, I., Asp, T. & Geu-Flores, Fernando, 2016, In: Planta Medica. 82, S 01, 1 p.Research output: Contribution to journal › Conference abstract in journal › Research › peer-review
- 2017
- Published
An NPF transporter exports a central monoterpene indole alkaloid intermediate from the vacuole
Payne, R., Xu, Deyang, Foureau, E., Ines Soares Teto Carqueijeiro, M., Oudin, A., Dugé de Bernonville, T., Novák, V., Burow, Meike, Olsen, C. E., Jones, D. M., C. Tatsis, E., Pendleton, A., Halkier, Barbara Ann, Geu-Flores, Fernando, Courdavault, V., Nour-Eldin, Hussam Hassan & O'Connor, S. E., 2017, In: Nature Plants. 3, 9 p., 16208.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Transcript profiling of a bitter variety of narrow-leafed lupin to discover alkaloid biosynthetic genes
Yang, T., Nagy, I., Mancinotti, Davide, Otterbach, S. L., Andersen, T. B., Motawie, Mohammed Saddik, Asp, T. & Geu-Flores, Fernando, 2017, In: Journal of Experimental Botany. 68, 20, p. 5527-5537 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Eliminating vicine and convicine, the main anti-nutritional factors restricting faba bean usage
Khazaei, H., Purves, R. W., Hughes, J., Link, W., O'Sullivan, D. M., Schulman, A. H., Björnsdotter, E., Geu-Flores, Fernando, Nadzieja, M., Andersen, S. U., Stougaard, J., Vandenberg, A. & Stoddard, F. L., Sep 2019, In: Trends in Food Science and Technology. 91, p. 549-556Research output: Contribution to journal › Review › Research › peer-review
- Published
Quinolizidine alkaloids are transported to seeds of bitter narrow-leafed lupin
Otterbach, S. L., Yang, T., Kato, L., Janfelt, Christian & Geu-Flores, Fernando, 15 Oct 2019, In: Journal of Experimental Botany. 70, 20, p. 5799-5808Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
- Published
High-quality genome sequence of white lupin provides insight into soil exploration and seed quality
Hufnagel, B., Marques, A., Soriano, A., Marquès, L., Divol, F., Doumas, P., Sallet, E., Mancinotti, D., Carrere, S., Marande, W., Arribat, S., Keller, J., Huneau, C., Blein, T., Aimé, D., Laguerre, M., Taylor, J., Schubert, V., Nelson, M., Geu-Flores, F. & 8 others, , 2020, In: Nature Communications. 11, 1, 12 p., 492.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Bioengineering potato plants to produce benzylglucosinolate for improved broad-spectrum pest and disease resistance
González-Romero, M. E., Rivera, C., Cancino, K., Geu-Flores, Fernando, Cosio, E. G., Ghislain, M. & Halkier, Barbara Ann, 2021, In: Transgenic Research. 30, p. 649-660 12 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Development and application of a virus-induced gene silencing protocol for the study of gene function in narrow-leafed lupin
Mancinotti, Davide, Rodriguez, M. C., Frick, Karen Michiko, Dueholm, B., Jepsen, D. G., Agerbirk, Niels & Geu-Flores, Fernando, 2021, In: Plant Methods. 17, 1, 13 p., 131.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
VC1 catalyses a key step in the biosynthesis of vicine in faba bean
Björnsdotter, E., Nadzieja, M., Chang, W., Escobar-Herrera, L., Mancinotti, Davide, Angra, D., Xia, Xinxing, Tacke, R., Khazaei, H., Crocoll, C., Vandenberg, A., Link, W., Stoddard, F. L., O'Sullivan, D. M., Stougaard, J., Schulman, A. H., Andersen, S. U. & Geu-Flores, Fernando, 2021, In: Nature Plants. 7, p. 923–931Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
A gene cluster in Ginkgo biloba encodes unique multifunctional cytochrome P450s that initiate ginkgolide biosynthesis
Forman, Victor, Luo, Dan, Geu-Flores, Fernando, Lemcke, René, Nelson, D., Kampranis, Sotirios, Stærk, Dan, Møller, Birger Lindberg & Pateraki, Irini, 2022, In: Nature Communications. 13, 14 p., 5143.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Biosynthesis of quinolizidine alkaloids in lupins: mechanistic considerations and prospects for pathway elucidation
Mancinotti, Davide, Frick, Karen Michiko & Geu-Flores, Fernando, 2022, In: Natural Product Reports. 39, 7, p. 1423-1437 15 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Prospects to improve the nutritional quality of crops. Food and Energy Security
Scharff, L., Saltenis, V. L. R., Jensen, P. E., Baekelandt, A., Burgess, A. J., Burow, M., Ceriotti, A., Cohan, J-P., Geu-Flores, F., Halkier, B. A., Haslam, R. P., Inzé, D., Lankhorst, R. K., Murchie, E., Napier, J. A., Nacry, P., Parry, M. A. J., Santino, A., Scarano, A., Sparvoli, F. & 2 others, , 2022, In: Food and Energy Security. 11, 1, 14 p., e327.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
An improved Nicotiana benthamiana bioproduction chassis provides novel insights into nicotine biosynthesis
Vollheyde, K., Dudley, Q. M., Yang, T., Oz, M. T., Mancinotti, Davide, Fedi, M. O., Heavens, D., Linsmith, G., Chhetry, M., Smedley, M. A., Harwood, W. A., Swarbreck, D., Geu-Flores, Fernando & Patron, N. J., 2023, In: New Phytologist. 240, 1, p. 302-317 16 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The aerial epidermis is a major site of quinolizidine alkaloid biosynthesis in narrow-leafed lupin
Frick, Karen Michiko, Lorensen, Marcus Daniel B B, Esteban, E., Pasha, A., Schulz, Alexander, Provart, N. J., Janfelt, Christian, Nour-Eldin, Hussam Hassan & Geu-Flores, Fernando, 2023, bioRxiv, 18 p.Research output: Working paper › Preprint
- Published
The causal mutation leading to sweetness in modern white lupin cultivars
Mancinotti, Davide, Czepiel, K., Taylor, J. L., Galehshahi, H. G., Møller, L. A., Jensen, M. K., Motawie, Mohammed Saddik, Hufnagel, B., Soriano, A., Yeheyis, L., Kjaerulff, Louise, Péret, B., Stærk, Dan, Wendt, T., Nelson, M. N., Kroc, M. & Geu-Flores, Fernando, 2023, In: Science Advances. 9, 31, 10 p., eadg8866.Research output: Contribution to journal › Journal article › Research › peer-review
ID: 37992063
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Modulation of sulfur metabolism enables efficient glucosinolate engineering
Research output: Contribution to journal › Journal article › Research › peer-review
Published -
892
downloads
Conversion of substrate analogs suggests a Michael cyclization in iridoid biosynthesis
Research output: Contribution to journal › Journal article › Research › peer-review
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276
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Transcript profiling of a bitter variety of narrow-leafed lupin to discover alkaloid biosynthetic genes
Research output: Contribution to journal › Journal article › Research › peer-review
Published