Thomas Günther-Pomorski

Thomas Günther-Pomorski

Professor


  1. Published

    Visualizing NBD-lipid Uptake in Mammalian Cells by Confocal Microscopy

    Baum, Julia Franziska, Bredegaard, L., Herrera, S. A. & Pomorski, Thomas Guenther, 2023, In: Bio-protocol. 13, 13, 16 p., e4771.

    Research output: Contribution to journalJournal articleResearchpeer-review

  2. Published

    Visualizing Loss of Plasma Membrane Lipid Asymmetry Using Annexin V Staining

    Baum, Julia Franziska, Uzun, Huriye Deniz & Pomorski, Thomas Guenther, 2023, In: Bio-protocol. 13, 14, e4754.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. Published

    Transbilayer dynamics of phospholipids in the plasma membrane of the Leishmania genus

    Santos, M. G. D., Muxel, S. M., Zampieri, R. A., Pomorski, Thomas Guenther & Floeter-Winter, L. M., 2013, In: P L o S One. 8, 1, 7 p., e55604.

    Research output: Contribution to journalJournal articleResearchpeer-review

  4. Published

    Time-resolved small-angle neutron scattering as a probe for the dynamics of lipid exchange between human lipoproteins and naturally derived membranes

    Maric, S., Lind, T. K., Raida, M. R., Bengtsson, E., Fredrikson, G. N., Rogers, S., Moulin, M., Haertlein, M., Forsyth, V. T., Wenk, M. R., Pomorski, Thomas Guenther, Arnebrant, T., Lund, R. & Cárdenas, M., 2019, In: Scientific Reports. 9, p. 1-14 7591.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    The yeast plasma membrane ATP binding cassette (ABC) transporter aus1

    Marek, M., Milles, S., Schreiber, G., Daleke, D. L., Dittmar, G., Herrmann, A., Müller, P. & Pomorski, Thomas Guenther, 2011, In: Journal of Biological Chemistry. 286, 24, p. 21835–21843 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    The transport mechanism of P4 ATPase lipid flippases

    Lopez Marques, Rosa Laura, Gourdon, Pontus Emanuel, Pomorski, Thomas Guenther & Palmgren, Michael, 2020, In: Biochemical Journal. 477, 19, p. 3769-3790 22 p.

    Research output: Contribution to journalReviewResearchpeer-review

  7. Published

    The lipid head group is the key element for substrate recognition by the P4 ATPase ALA2: A phosphatidylserine flippase

    Theorin, L., Faxén, K., Sørensen, D. M., Migotti, R., Dittmar, G., Schiller, J., Daleke, D. L., Palmgren, Michael, Lopez Marques, Rosa Laura & Pomorski, Thomas Guenther, 6 Mar 2019, In: Biochemical Journal. 476, 5, p. 783-794

    Research output: Contribution to journalJournal articleResearchpeer-review

  8. Published

    The dendrimer impact on vesicles can be tuned based on the lipid bilayer charge and the presence of albumin

    Ruggeri, F., Åkesson, A. K. L., Chapuis, P., Nielsen, Catherine S., Pomorski, Thomas Guenther, Monopoli, M. P., Dawson, K. A., Pomorski, Thomas Guenther & Cardenas Gomez, M., 2013, In: Soft Matter. 9, 37, p. 8862-8870 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. Published

    The P5A ATPase Spf1p is stimulated by phosphatidylinositol 4-phosphate and influences cellular sterol homeostasis

    Sørensen, D. M., Holen, H. W., Pedersen, J. T., Martens, Helle Jakobe, Silvestro, D., Stanchev, L. D., Costa, S. R., Pomorski, Thomas Guenther, Lopez Marques, Rosa Laura & Palmgren, Michael, 15 Apr 2019, In: Molecular Biology of the Cell. 30, 9, p. 1069-1084

    Research output: Contribution to journalJournal articleResearchpeer-review

  10. Published

    Synthesis and thermotropic phase behavior of four glycoglycerolipids

    Hogendorf, W. F. J., Jagalski, V., Pomorski, Thomas Guenther, Bols, Mikael, Cardenas Gomez, M. & Pedersen, Christian Marcus, 2013, In: Molecules. 18, 11, p. 13546-13573 28 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Synthesis and Purification of Lipid-conjugated Fluorescent pH Sensors

    Wiesner, W., Kühnel, R. M. & Pomorski, Thomas Guenther, 2023, In: Bio-protocol. 13, 11, e4694.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Structure and mechanism of ATP-dependent phospholipid transporters

    Lopez Marques, Rosa Laura, Poulsen, L. R., Bailly, A., Geisler, M., Pomorski, Thomas Guenther & Palmgren, Michael, 2015, In: Biochimica et Biophysica Acta - General Subjects. 1850, 3, p. 461-475 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    Structural requirements for membrane binding of human guanylate-binding protein 1

    Sistemich, L., Dimitrov Stanchev, L., Kutsch, M., Roux, A., Pomorski, Thomas Guenther & Herrmann, C., 2021, In: FEBS Journal. 288, 13, p. 4098-4114

    Research output: Contribution to journalJournal articleResearchpeer-review

  14. Published

    Stealth carriers for low-resolution structure determination of membrane proteins in solution

    Maric, S., Skar-Gislinge, Nicholas, Midtgaard, S., Thygesen, Mikkel Boas, Schiller, J., Frielinghaus, H., Moulin, M., Haertlein, M., Forsyth, V. T., Pomorski, Thomas Guenther & Arleth, Lise, 2014, In: Acta Crystallographica. Section D: Biological Crystallography. 70, 2, p. 317-328 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  15. Published

    Specific activation of the plant P-type plasma membrane H+-ATPase by lysophospholipids depends on the autoinhibitory N- and C-terminal domains

    Wielandt, A. G., Pedersen, J. T., Falhof, J., Kemmer, G. C., Lund, A., Ekberg, K., Fuglsang, Anja Thoe, Pomorski, Thomas Guenther, Buch-Pedersen, M. J. & Palmgren, Michael, 2015, In: The Journal of Biological Chemistry. 290, 26, p. 16281-16291 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Small-angle Neutron Scattering Shows that the Solution Structures of the Bacterial Mg2+-Channel CorA are Overall Similar with and without Mg2+ Bound

    Arleth, Lise, Johansen, Nicolai Tidemand, Bengtsen, T., Larsen, A. H., Tidemand, Frederik Grønbæk, Pomorski, Thomas Guenther & Lindorff-Larsen, Kresten, 7 Feb 2020, In: Biophysical Journal. 118, 3, Suppl. 1, p. 12A 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  17. Published

    Single Vesicle Fluorescence-Bleaching Assay for Multi-Parameter Analysis of Proteoliposomes by Total Internal Reflection Fluorescence Microscopy

    Veit, S., Paweletz, L. C., Bohr, S. S., Menon, A. K., Hatzakis, Nikos & Pomorski, Thomas Guenther, 2022, In: ACS applied materials & interfaces. 14, 26, p. 29659−29667 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Short-chain lipid-conjugated pH sensors for imaging of transporter activities in reconstituted systems and living cells

    Kuehnel, R. M., Grifell-Junyent, M., Jørgensen, I. L., Kemmer, G. C., Schiller, J., Palmgren, Michael, Justesen, B. H. & Pomorski, Thomas Guenther, 2019, In: Analyst. 144, 9, p. 3030-3037

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. Published

    Serum albumin promotes ATP-binding cassette transporter-dependent sterol uptake in yeast

    Marek, M., Silvestro, D., Fredslund, M. D., Andersen, T. G. & Pomorski, Thomas Guenther, 2014, In: FEMS Yeast Research. 14, 8, p. 1223-1233 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  20. Published

    Role of post-translational modifications at the β-subunit ectodomain in complex association with a promiscuous plant P4-ATPase

    Costa, S., Marek, M., Axelsen, Kristian Buhl, Theorin, L., Pomorski, Thomas Guenther & Lopez Marques, Rosa Laura, 2016, In: Biochemical Journal. 473, 11, p. 1605-1615 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Role of lipid transporters in fungal physiology and pathogenicity

    Rizzo, J., Stanchev, L. D., da Silva, V. K. A., Nimrichter, L., Pomorski, Thomas Guenther & Rodrigues, M. L., 2019, In: Computational and Structural Biotechnology Journal. 17, p. 1278-1289 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  22. Published

    Resolving active ion transport at the single molecule level for the first time

    Veshaguri, S., Christensen, S. M., Kemmer, G. C., Møller, M. P., Ghale, G., Lohr, C., Christensen, A. L., Justesen, B. H., Jørgensen, I. L., Schiller, J., Hatzakis, Nikos, Grabe, M., Pomorski, Thomas Guenther & Stamou, Dimitrios, 2016, In: Biophysical Journal. 110, 3, p. 179A 1 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  23. Published

    Reconstitution of ATP-dependent lipid transporters: gaining insight into molecular characteristics, regulation, and mechanisms

    Herrera, S. A. & Pomorski, Thomas Guenther, 2023, In: Bioscience Reports. 43, 8, 17 p.

    Research output: Contribution to journalReviewResearchpeer-review

  24. Published

    Purification and characterisation of the yeast plasma membrane ATP binding cassette transporter Pdr11p

    Laub, K. R., Marek, M., Stanchev, L. D., Herrera, S. A., Kanashova, T., Bourmaud, A., Dittmar, G. & Pomorski, Thomas Guenther, 2017, In: PLOS ONE. 12, 9, 18 p., e0184236.

    Research output: Contribution to journalJournal articleResearchpeer-review

  25. Published

    Pumping lipids with P4-ATPases

    Lopez Marques, Rosa Laura, C.M. Holthuis, J. & Pomorski, Thomas Guenther, 2011, In: Biological Chemistry. 392, 1-2, p. 67-76 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  26. Published

    Pseudohyphal growth in Saccharomyces cerevisiae involves protein kinase-regulated lipid flippases

    Frøsig, M. M., Costa, S. R., Liesche, J., Østerberg, J. T., Hanisch, S., Kjeldgaard-Nintemann, Sebastian J, Sørensen, Helle, Palmgren, Michael, Pomorski, Thomas Guenther & Lopez Marques, Rosa Laura, 6 Aug 2020, In: Journal of Cell Science. 133, 15, 235994.

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    Primary cell wall inspired micro containers as a step towards a synthetic plant cell

    Paulraj, T., Wennmalm, S., Wieland, D. C. F., Riazanova, A. V., Dėdinaitė, A., Pomorski, Thomas Guenther, Cárdenas, M. & Svagan, A. J., 2020, In: Nature Communications. 11, 1, 11 p., 958.

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Phospholipid flipping involves a central cavity in P4 ATPases

    Jensen, M. S., Costa, S., Duelli, A. S., Andersen, P. A., Poulsen, L. R., Stanchev, L. D., Gourdon, Pontus Emanuel, Palmgren, Michael, Pomorski, Thomas Guenther & Lopez Marques, Rosa Laura, 2017, In: Scientific Reports. 7, 13 p., 17621.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    P4-ATPases: lipid flippases in cell membranes

    Lopez Marques, Rosa Laura, Theorin, L., Palmgren, Michael & Pomorski, Thomas Guenther, 2014, In: Pflügers Archiv - European Journal of Physiology. 466, 7, p. 1227-1240 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  30. Published

    P4-ATPases: new elements of the secretory pathway?

    Lopez Marques, Rosa Laura, Poulsen, L. R., Meffert, K., Pomorski, Thomas Guenther & Palmgren, Michael, 2009. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  31. Published

    P-type atpase apt1 of the fungal pathogen Cryptococcus neoformans is a lipid flippase of broad substrate specificity

    Stanchev, L. D., Rizzo, J., Peschel, R., Pazurek, L. A., Bredegaard, L., Veit, S., Laerbusch, S., Rodrigues, M. L., Lopez Marques, Rosa Laura & Pomorski, Thomas Guenther, 2021, In: Journal of Fungi. 7, 10, 16 p., 843.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    Oxetane ring formation in taxol biosynthesis is catalyzed by a bifunctional cytochrome P450 enzyme

    Zhao, Yong, zpm303, zpm303, Xie, Yuman, Duan, Y. T., Andeadelli, A., Pateraki, Irini, Makris, A. M., Pomorski, Thomas Guenther, Stærk, Dan & Kampranis, Sotirios, 2024, In: Journal of the American Chemical Society. 146, p. 801-810

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Organization of fluorescent cholesterol analogs in lipid bilayers — Lessons from cyclodextrin extraction

    Milles, S., Meyer, T., Scheidt, H. A., Schwarzer, R., Thomas, L., Marek, M., Szente, L., Bittman, R., Herrmann, A., Pomorski, Thomas Guenther, Huster, D. & Müller, P., 2013, In: B B A - Biomembranes. 1828, 8, p. 1822-1828 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Novel tool to quantify cell wall porosity relates wall structure to cell growth and drug uptake

    Liu, X., Li, J., Zhao, H., Liu, B., Pomorski, Thomas Guenther, Chen, S. & Liesche, J., Apr 2019, In: Journal of Cell Biology. 218, 4, p. 1407-1420

    Research output: Contribution to journalJournal articleResearchpeer-review

  35. Published

    Novel secretory pathway pumps

    Poulsen, L. R., Lopez Marques, Rosa Laura, Sørensen, D. M., Pomorski, Thomas Guenther, Buch Pedersen, M. & Palmgren, Michael, 2010, In: Biochimica et Biophysica Acta - Bioenergetics. 1797, Suppl., p. 42 1 p.

    Research output: Contribution to journalConference abstract in journalResearch

  36. Published

    Novel approach to measure the size of plasma-membrane nanodomains in single molecule localization microscopy

    Ziomkiewicz, I., Sporring, Jon, Pomorski, Thomas Guenther & Schulz, Alexander, 2015, In: Cytometry. Part A. 87, 9, p. 868-877

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    Non-invasive Quantification of Cell Wall Porosity by Fluorescence Quenching Microscopy

    Liu, X., Pomorski, Thomas Guenther & Liesche, J., 2019, In: Bio-protocol. 9, 16

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    NBD-lipid Uptake Assay for Mammalian Cell Lines

    Herrera, S. A., Grifell-Junyent, M. & Pomorski, Thomas Guenther, 2022, In: Bio-protocol. 12, 4, 258649.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Model cell membranes: discerning lipid and protein contributions in shaping the cell

    Pomorski, Thomas Guenther, Nylander, T. & Cardenas Gomez, M., 2014, In: Advances in Colloid and Interface Science. 205, p. 207-220 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  40. Published

    Mg2+-dependent conformational equilibria in CorA and an integrated view on transport regulation

    Johansen, Nicolai Tidemand, Bonaccorsi, M., Bengtsen, T., Nørgrd Larsen, Andreas, Tidemand, Frederik Grønbæk, Pedersen, Martin Cramer, Huda, P., Berndtsson, J., Darwish, T., Yepuri, N. R., Martel, A., Pomorski, Thomas Guenther, Bertarello, A., Sansom, M., Rapp, M., Crehuet, R., Schubeis, T., Lindorff-Larsen, Kresten, Pintacuda, G. & Arleth, Lise, 2022, In: eLife. 11, 35 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  41. Published

    Metabolic incorporation of unsaturated fatty acids into boar spermatozoa lipids and de novo formation of diacylglycerols

    Svetlichnyy, V., Müller, P., Pomorski, Thomas Guenther, Schulze, M., Schiller, J. & Müller, K., 2014, In: Chemistry and Physics of Lipids. 177, p. 41-50 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  42. Published

    Membrane protein reconstitution into giant unilamellar vesicles: a review on current techniques

    Jørgensen, I. L., Kemmer, G. C. & Pomorski, Thomas Guenther, 2017, In: European Biophysics Journal. 46, 2, p. 103-119 17 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Measuring in vitro ATPase Activity with High Sensitivity Using Radiolabeled ATP

    Veit, S. & Pomorski, Thomas Guenther, 2023, In: Bio-protocol. 13, 10, 14 p., e4676.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    Measuring H+ pumping and membrane potential formation in sealed membrane vesicle systems

    Wielandt, A. G., Palmgren, Michael, Fuglsang, Anja Thoe, Pomorski, Thomas Guenther & Justesen, B. H., 2016, P-Type ATPases: methods and protocols. Bublitz, M. (ed.). Springer, Vol. Part II. p. 171-180 10 p. (Methods in Molecular Biology, Vol. 1377).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  45. Published

    Lipids in the city: the 9. yeast lipid conference, Berlin, Germany, 2009

    Lang, C., Pomorski, Thomas Guenther & Daum, G., 2009. 3 p.

    Research output: Contribution to conferencePaperResearch

  46. Published

    Lipid-conjugated fluorescent pH sensors for monitoring pH changes in reconstituted membrane systems

    Kemmer, G. C., Bogh, S. A., Urban, M., Palmgren, Michael, Vosch, Tom, Schiller, J. & Pomorski, Thomas Guenther, 2015, In: Analyst. 140, 18, p. 6313-6320 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Lipid somersaults: uncovering the mechanisms of protein-mediated lipid flipping

    Pomorski, Thomas Guenther & Menon, A. K., 2016, In: Progress in Lipid Research. 64, p. 69-84 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. Published

    Label-Free Fluorescence Quantification of Hydrolytic Enzyme Activity on Native Substrates Reveals How Lipase Function Depends on Membrane Curvature

    Bohr, S. S., Thorlaksen, C., Kühnel, R. M., Pomorski, Thomas Guenther & Hatzakis, Nikos, 16 Jun 2020, In: Langmuir. 36, 23, p. 6473-6481 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  49. Published

    LEGO-inspired drug design: unveiling a class of Benzo[d]thiazoles containing a 3,4-Dihydroxyphenyl moiety as plasma membrane H+-ATPase inhibitors

    Thanh Tung, T., Dao, T. T., Grifell Junyent, M., Palmgren, Michael, Pomorski, Thomas Guenther, Fuglsang, Anja Thoe, Christensen, Søren Brøgger & Nielsen, J., 2018, In: ChemMedChem. 13, 1, 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Isolation of monodisperse nanodisc-reconstituted membrane proteins using free flow electrophoresis

    Justesen, B. H., Laursen, Tomas, Weber, G., Fuglsang, Anja Thoe, Møller, Birger Lindberg & Pomorski, Thomas Guenther, 2013, In: Analytical Chemistry. 85, 7, p. 3497-3500 4 p.

    Research output: Contribution to journalLetterResearchpeer-review

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