Sugar transporters enable a leaf beetle to accumulate plant defense compounds

Research output: Contribution to journal › Journal article › Research › peer-review

Standard

Sugar transporters enable a leaf beetle to accumulate plant defense compounds. / Yang, Zhi Ling; Nour-Eldin, Hussam Hassan; Hänniger, Sabine; Reichelt, Michael; Crocoll, Christoph; Seitz, Fabian; Vogel, Heiko; Beran, Franziska.

In: Nature Communications, Vol. 12, No. 1, 2658, 2021.

Research output: Contribution to journal › Journal article › Research › peer-review

Harvard

Yang, ZL, Nour-Eldin, HH, Hänniger, S, Reichelt, M, Crocoll, C, Seitz, F, Vogel, H & Beran, F 2021, 'Sugar transporters enable a leaf beetle to accumulate plant defense compounds', Nature Communications, vol. 12, no. 1, 2658. https://doi.org/10.1038/s41467-021-22982-8

APA

Yang, Z. L., Nour-Eldin, H. H., Hänniger, S., Reichelt, M., Crocoll, C., Seitz, F., Vogel, H., & Beran, F. (2021). Sugar transporters enable a leaf beetle to accumulate plant defense compounds. Nature Communications, 12(1), [2658]. https://doi.org/10.1038/s41467-021-22982-8

Vancouver

Yang ZL, Nour-Eldin HH, Hänniger S, Reichelt M, Crocoll C, Seitz F et al. Sugar transporters enable a leaf beetle to accumulate plant defense compounds. Nature Communications. 2021;12(1). 2658. https://doi.org/10.1038/s41467-021-22982-8

Author

Yang, Zhi Ling ; Nour-Eldin, Hussam Hassan ; Hänniger, Sabine ; Reichelt, Michael ; Crocoll, Christoph ; Seitz, Fabian ; Vogel, Heiko ; Beran, Franziska. / Sugar transporters enable a leaf beetle to accumulate plant defense compounds. In: Nature Communications. 2021 ; Vol. 12, No. 1.

Bibtex

@article{1c04308134f04255bd119c57e221f202,
title = "Sugar transporters enable a leaf beetle to accumulate plant defense compounds",
abstract = "Many herbivorous insects selectively accumulate plant toxins for defense against predators; however, little is known about the transport processes that enable insects to absorb and store defense compounds in the body. Here, we investigate how a specialist herbivore, the horseradish flea beetle, accumulates glucosinolate defense compounds from Brassicaceae in the hemolymph. Using phylogenetic analyses of coleopteran major facilitator superfamily transporters, we identify a clade of glucosinolate-specific transporters (PaGTRs) belonging to the sugar porter family. PaGTRs are predominantly expressed in the excretory system, the Malpighian tubules. Silencing of PaGTRs leads to elevated glucosinolate excretion, significantly reducing the levels of sequestered glucosinolates in beetles. This suggests that PaGTRs reabsorb glucosinolates from the Malpighian tubule lumen to prevent their loss by excretion. Ramsay assays corroborated the selective retention of glucosinolates by Malpighian tubules of P. armoraciae in situ. Thus, the selective accumulation of plant defense compounds in herbivorous insects can depend on the ability to prevent excretion.",
author = "Yang, {Zhi Ling} and Nour-Eldin, {Hussam Hassan} and Sabine H{\"a}nniger and Michael Reichelt and Christoph Crocoll and Fabian Seitz and Heiko Vogel and Franziska Beran",
note = "Publisher Copyright: {\textcopyright} 2021, The Author(s).",
year = "2021",
doi = "10.1038/s41467-021-22982-8",
language = "English",
volume = "12",
journal = "Nature Communications",
issn = "2041-1723",
publisher = "nature publishing group",
number = "1",

}

RIS

TY - JOUR

T1 - Sugar transporters enable a leaf beetle to accumulate plant defense compounds

AU - Yang, Zhi Ling

AU - Nour-Eldin, Hussam Hassan

AU - Hänniger, Sabine

AU - Reichelt, Michael

AU - Crocoll, Christoph

AU - Seitz, Fabian

AU - Vogel, Heiko

AU - Beran, Franziska

N1 - Publisher Copyright: © 2021, The Author(s).

PY - 2021

Y1 - 2021

N2 - Many herbivorous insects selectively accumulate plant toxins for defense against predators; however, little is known about the transport processes that enable insects to absorb and store defense compounds in the body. Here, we investigate how a specialist herbivore, the horseradish flea beetle, accumulates glucosinolate defense compounds from Brassicaceae in the hemolymph. Using phylogenetic analyses of coleopteran major facilitator superfamily transporters, we identify a clade of glucosinolate-specific transporters (PaGTRs) belonging to the sugar porter family. PaGTRs are predominantly expressed in the excretory system, the Malpighian tubules. Silencing of PaGTRs leads to elevated glucosinolate excretion, significantly reducing the levels of sequestered glucosinolates in beetles. This suggests that PaGTRs reabsorb glucosinolates from the Malpighian tubule lumen to prevent their loss by excretion. Ramsay assays corroborated the selective retention of glucosinolates by Malpighian tubules of P. armoraciae in situ. Thus, the selective accumulation of plant defense compounds in herbivorous insects can depend on the ability to prevent excretion.

AB - Many herbivorous insects selectively accumulate plant toxins for defense against predators; however, little is known about the transport processes that enable insects to absorb and store defense compounds in the body. Here, we investigate how a specialist herbivore, the horseradish flea beetle, accumulates glucosinolate defense compounds from Brassicaceae in the hemolymph. Using phylogenetic analyses of coleopteran major facilitator superfamily transporters, we identify a clade of glucosinolate-specific transporters (PaGTRs) belonging to the sugar porter family. PaGTRs are predominantly expressed in the excretory system, the Malpighian tubules. Silencing of PaGTRs leads to elevated glucosinolate excretion, significantly reducing the levels of sequestered glucosinolates in beetles. This suggests that PaGTRs reabsorb glucosinolates from the Malpighian tubule lumen to prevent their loss by excretion. Ramsay assays corroborated the selective retention of glucosinolates by Malpighian tubules of P. armoraciae in situ. Thus, the selective accumulation of plant defense compounds in herbivorous insects can depend on the ability to prevent excretion.

U2 - 10.1038/s41467-021-22982-8

DO - 10.1038/s41467-021-22982-8

M3 - Journal article

C2 - 33976202

AN - SCOPUS:85105727172

VL - 12

JO - Nature Communications

JF - Nature Communications

SN - 2041-1723

IS - 1

M1 - 2658

ER -

ID: 273579872