Thomas Günther-Pomorski
Professor
Section for Transport Biology
Thorvaldsensvej 40
1871 Frederiksberg C
- 2016
- Published
Resolving active ion transport at the single molecule level for the first time
Veshaguri, S., Christensen, S. M., Kemmer, G. C., Møller, M. P., Ghale, G., Lohr, C., Christensen, A. L., Justesen, B. H., Jørgensen, I. L., Schiller, J., Hatzakis, Nikos, Grabe, M., Pomorski, Thomas Guenther & Stamou, Dimitrios, 2016, In: Biophysical Journal. 110, 3, p. 179A 1 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of post-translational modifications at the β-subunit ectodomain in complex association with a promiscuous plant P4-ATPase
Costa, S., Marek, M., Axelsen, Kristian Buhl, Theorin, L., Pomorski, Thomas Guenther & Lopez Marques, Rosa Laura, 2016, In: Biochemical Journal. 473, 11, p. 1605-1615 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2017
- Published
Membrane protein reconstitution into giant unilamellar vesicles: a review on current techniques
Jørgensen, I. L., Kemmer, G. C. & Pomorski, Thomas Guenther, 2017, In: European Biophysics Journal. 46, 2, p. 103-119 17 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Phospholipid flipping involves a central cavity in P4 ATPases
Jensen, M. S., Costa, S., Duelli, A. S., Andersen, P. A., Poulsen, L. R., Stanchev, L. D., Gourdon, Pontus Emanuel, Palmgren, Michael, Pomorski, Thomas Guenther & Lopez Marques, Rosa Laura, 2017, In: Scientific Reports. 7, 13 p., 17621.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Purification and characterisation of the yeast plasma membrane ATP binding cassette transporter Pdr11p
Laub, K. R., Marek, M., Stanchev, L. D., Herrera, S. A., Kanashova, T., Bourmaud, A., Dittmar, G. & Pomorski, Thomas Guenther, 2017, In: PLOS ONE. 12, 9, 18 p., e0184236.Research output: Contribution to journal › Journal article › Research › peer-review
- 2018
- Published
Ergosterol is mainly located in the cytoplasmic leaflet of the yeast plasma membrane
Solanko, L. M., Sullivan, D. P., Sere, Y. Y., Szomek, M., Lunding, A., Solanko, K., Pizovic, A., Stanchev, L. D., Pomorski, Thomas Guenther, Menon, A. K. & Wüstner, D., 2018, In: Traffic. 19, 3, p. 198-214 7 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
LEGO-inspired drug design: unveiling a class of Benzo[d]thiazoles containing a 3,4-Dihydroxyphenyl moiety as plasma membrane H+-ATPase inhibitors
Thanh Tung, T., Dao, T. T., Grifell Junyent, M., Palmgren, Michael, Pomorski, Thomas Guenther, Fuglsang, Anja Thoe, Christensen, Søren Brøgger & Nielsen, J., 2018, In: ChemMedChem. 13, 1, 11 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Cover Feature: LEGO-Inspired Drug Design: Unveiling a Class of Benzo[d ]thiazoles Containing a 3,4-Dihydroxyphenyl Moiety as Plasma Membrane H+ -ATPase Inhibitors (ChemMedChem 1/2018)
Tung, T., Dao, T. T., Junyent, M. G., Palmgren, Michael, Pomorski, Thomas Guenther, Fuglsang, Anja Thoe, Christensen, Søren Brøgger & Nielsen, J., 8 Jan 2018, In: ChemMedChem. 13, 1, 2 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2019
- Published
Non-invasive Quantification of Cell Wall Porosity by Fluorescence Quenching Microscopy
Liu, X., Pomorski, Thomas Guenther & Liesche, J., 2019, In: Bio-protocol. 9, 16Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Role of lipid transporters in fungal physiology and pathogenicity
Rizzo, J., Stanchev, L. D., da Silva, V. K. A., Nimrichter, L., Pomorski, Thomas Guenther & Rodrigues, M. L., 2019, In: Computational and Structural Biotechnology Journal. 17, p. 1278-1289 12 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Short-chain lipid-conjugated pH sensors for imaging of transporter activities in reconstituted systems and living cells
Kuehnel, R. M., Grifell-Junyent, M., Jørgensen, I. L., Kemmer, G. C., Schiller, J., Palmgren, Michael, Justesen, B. H. & Pomorski, Thomas Guenther, 2019, In: Analyst. 144, 9, p. 3030-3037Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Time-resolved small-angle neutron scattering as a probe for the dynamics of lipid exchange between human lipoproteins and naturally derived membranes
Maric, S., Lind, T. K., Raida, M. R., Bengtsson, E., Fredrikson, G. N., Rogers, S., Moulin, M., Haertlein, M., Forsyth, V. T., Wenk, M. R., Pomorski, Thomas Guenther, Arnebrant, T., Lund, R. & Cárdenas, M., 2019, In: Scientific Reports. 9, p. 1-14 7591.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The lipid head group is the key element for substrate recognition by the P4 ATPase ALA2: A phosphatidylserine flippase
Theorin, L., Faxén, K., Sørensen, D. M., Migotti, R., Dittmar, G., Schiller, J., Daleke, D. L., Palmgren, Michael, Lopez Marques, Rosa Laura & Pomorski, Thomas Guenther, 6 Mar 2019, In: Biochemical Journal. 476, 5, p. 783-794Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Novel tool to quantify cell wall porosity relates wall structure to cell growth and drug uptake
Liu, X., Li, J., Zhao, H., Liu, B., Pomorski, Thomas Guenther, Chen, S. & Liesche, J., Apr 2019, In: Journal of Cell Biology. 218, 4, p. 1407-1420Research output: Contribution to journal › Journal article › Research › peer-review
- Published
The P5A ATPase Spf1p is stimulated by phosphatidylinositol 4-phosphate and influences cellular sterol homeostasis
Sørensen, D. M., Holen, H. W., Pedersen, J. T., Martens, Helle Jakobe, Silvestro, D., Stanchev, L. D., Costa, S. R., Pomorski, Thomas Guenther, Lopez Marques, Rosa Laura & Palmgren, Michael, 15 Apr 2019, In: Molecular Biology of the Cell. 30, 9, p. 1069-1084Research output: Contribution to journal › Journal article › Research › peer-review
- 2020
Improved quantum efficiency in an engineered light harvesting/photosystem II super-complex for high current density biophotoanodes
Hartmann, V., Harris, D., Bobrowski, T., Ruff, A., Frank, A., Pomorski, Thomas Guenther, Rögner, M., Schuhmann, W., Adir, N. & Nowaczyk, M. M., 2020, In: Journal of Materials Chemistry A. 8, 29, p. 14463-14471 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Primary cell wall inspired micro containers as a step towards a synthetic plant cell
Paulraj, T., Wennmalm, S., Wieland, D. C. F., Riazanova, A. V., Dėdinaitė, A., Pomorski, Thomas Guenther, Cárdenas, M. & Svagan, A. J., 2020, In: Nature Communications. 11, 1, 11 p., 958.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
- Published
Small-angle Neutron Scattering Shows that the Solution Structures of the Bacterial Mg2+-Channel CorA are Overall Similar with and without Mg2+ Bound
Arleth, Lise, Johansen, Nicolai Tidemand, Bengtsen, T., Larsen, A. H., Tidemand, Frederik Grønbæk, Pomorski, Thomas Guenther & Lindorff-Larsen, Kresten, 7 Feb 2020, In: Biophysical Journal. 118, 3, Suppl. 1, p. 12A 1 p.Research output: Contribution to journal › Conference abstract in journal › Research
Agrobacterium tumefaciens Small Lipoprotein Atu8019 Is Involved in Selective Outer Membrane Vesicle (OMV) Docking to Bacterial Cells
Knoke, L. R., Herrera, S. A., Götz, K., Justesen, B. H., Pomorski, Thomas Guenther, Fritz, C., Schäkermann, S., Bandow, J. E. & Aktas, M., 9 Jun 2020, In: Frontiers in Microbiology. 11, 1228.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Label-Free Fluorescence Quantification of Hydrolytic Enzyme Activity on Native Substrates Reveals How Lipase Function Depends on Membrane Curvature
Bohr, S. S., Thorlaksen, C., Kühnel, R. M., Pomorski, Thomas Guenther & Hatzakis, Nikos, 16 Jun 2020, In: Langmuir. 36, 23, p. 6473-6481 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Pseudohyphal growth in Saccharomyces cerevisiae involves protein kinase-regulated lipid flippases
Frøsig, M. M., Costa, S. R., Liesche, J., Østerberg, J. T., Hanisch, S., Kjeldgaard-Nintemann, Sebastian J, Sørensen, Helle, Palmgren, Michael, Pomorski, Thomas Guenther & Lopez Marques, Rosa Laura, 6 Aug 2020, In: Journal of Cell Science. 133, 15, 235994.Research output: Contribution to journal › Journal article › Research › peer-review
- 2021
- Published
Endoplasmic reticulum phospholipid scramblase activity revealed after protein reconstitution into giant unilamellar vesicles containing a photostable lipid reporter
Mathiassen, P. P. M., Menon, A. K. & Pomorski, Thomas Guenther, 2021, In: Scientific Reports. 11, 1, 14 p., 14364.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Functional Significance of Conserved Cysteines in the Extracellular Loops of the ATP Binding Cassette Transporter Pdr11p
Stanchev, L. D., Marek, M., Xian, F., Klöhn, M., Silvestro, D., Dittmar, G., Lopez Marques, Rosa Laura & Pomorski, Thomas Guenther, 2021, In: Journal of Fungi. 7, 1, 16 p., 2.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Imaging of Lipid Uptake in Arabidopsis Seedlings Utilizing Fluorescent Lipids and Confocal Microscopy
Lopez Marques, Rosa Laura & Pomorski, Thomas Guenther, 2021, In: Bio-protocol. 11, 22, e4228.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
P-type atpase apt1 of the fungal pathogen Cryptococcus neoformans is a lipid flippase of broad substrate specificity
Stanchev, L. D., Rizzo, J., Peschel, R., Pazurek, L. A., Bredegaard, L., Veit, S., Laerbusch, S., Rodrigues, M. L., Lopez Marques, Rosa Laura & Pomorski, Thomas Guenther, 2021, In: Journal of Fungi. 7, 10, 16 p., 843.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Structural requirements for membrane binding of human guanylate-binding protein 1
Sistemich, L., Dimitrov Stanchev, L., Kutsch, M., Roux, A., Pomorski, Thomas Guenther & Herrmann, C., 2021, In: FEBS Journal. 288, 13, p. 4098-4114Research output: Contribution to journal › Journal article › Research › peer-review
- 2022
- Published
A Fluorescence-based Assay for Measuring Phospholipid Scramblase Activity in Giant Unilamellar Vesicles
Mathiassen, P. P. M. & Pomorski, Thomas Guenther, 2022, In: Bio-protocol. 12, 6, 19 p., 4366.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Autoinhibition and regulation by phosphoinositides of ATP8B1, a human lipid flippase associated with intrahepatic cholestatic disorders
Dieudonné, T., Herrera, S. A., Laursen, M. J., Lejeune, M., Stock, C., Slimani, K., Jaxel, C., Lyons, J. A., Montigny, C., Pomorski, Thomas Guenther, Nissen, P. & Lenoir, G., 2022, In: eLife. 11, 33 p., e75272.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
CDC50A is required for aminophospholipid transport and cell fusion in mouse C2C12 myoblasts
Grifell-Junyent, M., Baum, J. F., Valimets, S., Herrmann, A., Paulusma, C. C., Lopez Marques, Rosa Laura & Pomorski, Thomas Guenther, 2022, In: Journal of Cell Science. 135, 5, jcs258649.Research output: Contribution to journal › Journal article › Research › peer-review
Effects of 4-Br-A23187 on Bacillus subtilis cells and unilamellar vesicles reveal it to be a potent copper ionophore
Senges, C. H. R., Warmuth, H. L., Vázquez‐Hernández, M., Uzun, Huriye Deniz, Sagurna, L., Dietze, P., Schmidt, C., Mücher, B., Herlitze, S., Krämer, U., Ott, I., Pomorski, Thomas Guenther & Bandow, J. E., 2022, In: Proteomics. 22, 17, 12 p., 2200061.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
In vitro Assay to Evaluate Cation Transport of Ionophores
Uzun, Huriye Deniz, Vázquez-Hernández, M., Bandow, J. & Pomorski, Thomas Guenther, 2022, In: Bio-protocol. 12, 22, 11 p., e4552.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Mg2+-dependent conformational equilibria in CorA and an integrated view on transport regulation
Johansen, Nicolai Tidemand, Bonaccorsi, M., Bengtsen, T., Nørgrd Larsen, Andreas, Tidemand, Frederik Grønbæk, Pedersen, Martin Cramer, Huda, P., Berndtsson, J., Darwish, T., Yepuri, N. R., Martel, A., Pomorski, Thomas Guenther, Bertarello, A., Sansom, M., Rapp, M., Crehuet, R., Schubeis, T., Lindorff-Larsen, Kresten, Pintacuda, G. & Arleth, Lise, 2022, In: eLife. 11, 35 p.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
NBD-lipid Uptake Assay for Mammalian Cell Lines
Herrera, S. A., Grifell-Junyent, M. & Pomorski, Thomas Guenther, 2022, In: Bio-protocol. 12, 4, 258649.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Single Vesicle Fluorescence-Bleaching Assay for Multi-Parameter Analysis of Proteoliposomes by Total Internal Reflection Fluorescence Microscopy
Veit, S., Paweletz, L. C., Bohr, S. S., Menon, A. K., Hatzakis, Nikos & Pomorski, Thomas Guenther, 2022, In: ACS applied materials & interfaces. 14, 26, p. 29659−29667 9 p.Research output: Contribution to journal › Journal article › Research › peer-review
- 2023
- Published
Anionic Phospholipids Stimulate the Proton Pumping Activity of the Plant Plasma Membrane P-Type H+-ATPase
Paweletz, L. C., Holtbrügge, S. L., Löb, M., De Vecchis, D., Schäfer, L. V., Pomorski, Thomas Guenther & Justesen, B. H., 2023, In: International Journal of Molecular Sciences. 24, 17, 21 p., 13106.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Determination of membrane protein orientation upon liposomal reconstitution down to the single vesicle level
Veit, S., Paweletz, L. C. & Pomorski, Thomas Guenther, 2023, In: Biological Chemistry. 404, 7Research output: Contribution to journal › Review › Research › peer-review
- Published
Functional Analysis of the P-Type ATPases Apt2-4 from Cryptococcus neoformans by Heterologous Expression in Saccharomyces cerevisiae
Veit, S., Laerbusch, S., Lopez Marques, Rosa Laura & Pomorski, Thomas Guenther, 2023, In: Journal of Fungi. 9, 2, 16 p., 202.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Measuring in vitro ATPase Activity with High Sensitivity Using Radiolabeled ATP
Veit, S. & Pomorski, Thomas Guenther, 2023, In: Bio-protocol. 13, 10, 14 p., e4676.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Reconstitution of ATP-dependent lipid transporters: gaining insight into molecular characteristics, regulation, and mechanisms
Herrera, S. A. & Pomorski, Thomas Guenther, 2023, In: Bioscience Reports. 43, 8, 17 p.Research output: Contribution to journal › Review › Research › peer-review
- Published
Synthesis and Purification of Lipid-conjugated Fluorescent pH Sensors
Wiesner, W., Kühnel, R. M. & Pomorski, Thomas Guenther, 2023, In: Bio-protocol. 13, 11, e4694.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Visualizing Loss of Plasma Membrane Lipid Asymmetry Using Annexin V Staining
Baum, Julia Franziska, Uzun, Huriye Deniz & Pomorski, Thomas Guenther, 2023, In: Bio-protocol. 13, 14, e4754.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Visualizing NBD-lipid Uptake in Mammalian Cells by Confocal Microscopy
Baum, Julia Franziska, Bredegaard, L., Herrera, S. A. & Pomorski, Thomas Guenther, 2023, In: Bio-protocol. 13, 13, 16 p., e4771.Research output: Contribution to journal › Journal article › Research › peer-review
- 2024
- Published
Direct evidence of lipid transport by the Drs2–Cdc50 flippase upon truncation of its terminal regions
Herrera, S. A., Justesen, B. H., Dieudonné, T., Montigny, C., Nissen, P., Lenoir, G. & Pomorski, Thomas Guenther, 2024, In: Protein Science. 33, 3, 12 p., e4855.Research output: Contribution to journal › Journal article › Research › peer-review
- E-pub ahead of print
Electroformation of giant unilamellar vesicles from large liposomes
Uzun, Huriye Deniz, Tiris, Z., Czarnetzki, M., Lopez Marques, Rosa Laura & Pomorski, Thomas Guenther, 2024, (E-pub ahead of print) In: European Physical Journal: Special Topics.Research output: Contribution to journal › Journal article › Research › peer-review
- Published
Oxetane ring formation in taxol biosynthesis is catalyzed by a bifunctional cytochrome P450 enzyme
Zhao, Yong, zpm303, zpm303, Xie, Yuman, Duan, Y. T., Andeadelli, A., Pateraki, Irini, Makris, A. M., Pomorski, Thomas Guenther, Stærk, Dan & Kampranis, Sotirios, 2024, In: Journal of the American Chemical Society. 146, p. 801-810Research output: Contribution to journal › Journal article › Research › peer-review
ID: 9099036
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Leishmania promastigotes lack phosphatidylserine but bind annexin V upon permeabilization or miltefosine treatment
Research output: Contribution to journal › Journal article › Research › peer-review
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Lipid-conjugated fluorescent pH sensors for monitoring pH changes in reconstituted membrane systems
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Biologiske pumper og transport i vesikler
Research output: Other contribution › Net publication - Internet publication › Research
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