Transcytosis shuts the door for an unwanted guest
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Transcytosis shuts the door for an unwanted guest. / Nielsen, Mads Eggert; Thordal-Christensen, H.
In: Trends in Plant Science, Vol. 18, No. 11, 2013, p. 611-616.Research output: Contribution to journal › Journal article › Research › peer-review
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TY - JOUR
T1 - Transcytosis shuts the door for an unwanted guest
AU - Nielsen, Mads Eggert
AU - Thordal-Christensen, H.
PY - 2013
Y1 - 2013
N2 - Penetration resistance is a well-described plant defense process, in which SOLUBLE N-ETHYLMALEIMIDE-SENSITIVE-FACTOR ATTACHMENT RECEPTOR (SNARE) proteins have essential roles in membrane fusion processes. Strong focal accumulation of these proteins at the site of attack by powdery mildew fungi has been considered important for their function. However, recent insight indicates that transcytosis, leading to the formation of exosomes, has an important role in this defense and, furthermore, that strong accumulation of these SNARE proteins with the exosomes is biologically irrelevant. These findings alter the established function of SNAREs in penetration resistance; therefore, in this opinion, we propose that PEN1 and its SNARE partners function on an endosome in their control of penetration resistance.
AB - Penetration resistance is a well-described plant defense process, in which SOLUBLE N-ETHYLMALEIMIDE-SENSITIVE-FACTOR ATTACHMENT RECEPTOR (SNARE) proteins have essential roles in membrane fusion processes. Strong focal accumulation of these proteins at the site of attack by powdery mildew fungi has been considered important for their function. However, recent insight indicates that transcytosis, leading to the formation of exosomes, has an important role in this defense and, furthermore, that strong accumulation of these SNARE proteins with the exosomes is biologically irrelevant. These findings alter the established function of SNAREs in penetration resistance; therefore, in this opinion, we propose that PEN1 and its SNARE partners function on an endosome in their control of penetration resistance.
UR - http://www.scopus.com/inward/record.url?scp=84887022051&partnerID=8YFLogxK
U2 - 10.1016/j.tplants.2013.06.002
DO - 10.1016/j.tplants.2013.06.002
M3 - Journal article
C2 - 23870662
AN - SCOPUS:84887022051
VL - 18
SP - 611
EP - 616
JO - Trends in Plant Science
JF - Trends in Plant Science
SN - 1360-1385
IS - 11
ER -
ID: 102229213