While demands on global food production systems are on the rise, cultivable land is diminishing in area each year. Farming systems within arid and semi-arid regions have been estimated to lose up to 1.5 million hectares of arable land annually, due to increasing salinity levels (FAO 2015). Salt-induced losses are inevitably costly, with recent estimates upwards of $27 billion USD as a consequence of reduced crop productivity in areas subject to high saline levels (Qadir et al. 2014). This study employed a known beneficial fungal endophyte, Serendipita indica (previouslydescribed asPiriformospora indica) to combat salinity stress in tomato (Solanum lycopersicum) (Verma et al. 1998). Seedlings inoculated with S. indica were compared to control seedlings. Plants were subjected to three salinity stress levels ranging from no stress to high stress (in accordance FAO standards). Plant physiological parameters were recorded at three time intervals over the experimental period. S. indica provided S. lycopersicum with decipherable resilience under medium levels of salinity stress. These results provide a promising basis for the use of endophytes in saline entrenched areas, as a solution for future farming systems.