Saturated fats and health: A reassessment and proposal for food-based recommendations: JACC State-of-the-Art Review

Research output: Contribution to journalReviewpeer-review

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Saturated fats and health: A reassessment and proposal for food-based recommendations : JACC State-of-the-Art Review. / Astrup, Arne; Magkos, Faidon; Bier, Dennis M; Brenna, J Thomas; de Oliveira Otto, Marcia C; Hill, James O; King, Janet C; Mente, Andrew; Ordovas, Jose M; Volek, Jeff S; Yusuf, Salim; Krauss, Ronald M.

In: Journal of the American College of Cardiology, Vol. 76, No. 7, 2020, p. 844-857.

Research output: Contribution to journalReviewpeer-review

Harvard

Astrup, A, Magkos, F, Bier, DM, Brenna, JT, de Oliveira Otto, MC, Hill, JO, King, JC, Mente, A, Ordovas, JM, Volek, JS, Yusuf, S & Krauss, RM 2020, 'Saturated fats and health: A reassessment and proposal for food-based recommendations: JACC State-of-the-Art Review', Journal of the American College of Cardiology, vol. 76, no. 7, pp. 844-857. https://doi.org/10.1016/j.jacc.2020.05.077

APA

Astrup, A., Magkos, F., Bier, D. M., Brenna, J. T., de Oliveira Otto, M. C., Hill, J. O., King, J. C., Mente, A., Ordovas, J. M., Volek, J. S., Yusuf, S., & Krauss, R. M. (2020). Saturated fats and health: A reassessment and proposal for food-based recommendations: JACC State-of-the-Art Review. Journal of the American College of Cardiology, 76(7), 844-857. https://doi.org/10.1016/j.jacc.2020.05.077

Vancouver

Astrup A, Magkos F, Bier DM, Brenna JT, de Oliveira Otto MC, Hill JO et al. Saturated fats and health: A reassessment and proposal for food-based recommendations: JACC State-of-the-Art Review. Journal of the American College of Cardiology. 2020;76(7):844-857. https://doi.org/10.1016/j.jacc.2020.05.077

Author

Astrup, Arne ; Magkos, Faidon ; Bier, Dennis M ; Brenna, J Thomas ; de Oliveira Otto, Marcia C ; Hill, James O ; King, Janet C ; Mente, Andrew ; Ordovas, Jose M ; Volek, Jeff S ; Yusuf, Salim ; Krauss, Ronald M. / Saturated fats and health: A reassessment and proposal for food-based recommendations : JACC State-of-the-Art Review. In: Journal of the American College of Cardiology. 2020 ; Vol. 76, No. 7. pp. 844-857.

Bibtex

@article{c14ed0f6fd124b02bf50c8bbac3f1d72,
title = "Saturated fats and health: A reassessment and proposal for food-based recommendations: JACC State-of-the-Art Review",
abstract = "The recommendation to limit dietary saturated fatty acid (SFA) intake has persisted despite mounting evidence to the contrary. Most recent meta-analyses of randomized trials and observational studies found no beneficial effects of reducing SFA intake on cardiovascular disease (CVD) and total mortality, and instead found protective effects against stroke. Although SFAs increase low-density lipoprotein (LDL)-cholesterol, in most individuals, this is not due to increasing levels of small, dense LDL particles, but rather larger LDL which are much less strongly related to CVD risk. It is also apparent that the health effects of foods cannot be predicted by their content in any nutrient group, without considering the overall macronutrient distribution. Whole-fat dairy, unprocessed meat, eggs and dark chocolate are SFA-rich foods with a complex matrix that are not associated with increased risk of CVD. The totality of available evidence does not support further limiting the intake of such foods.",
keywords = "Faculty of Science, Cardiovascular disease, Diet, Saturated fat, Food matrix",
author = "Arne Astrup and Faidon Magkos and Bier, {Dennis M} and Brenna, {J Thomas} and {de Oliveira Otto}, {Marcia C} and Hill, {James O} and King, {Janet C} and Andrew Mente and Ordovas, {Jose M} and Volek, {Jeff S} and Salim Yusuf and Krauss, {Ronald M}",
note = "Copyright {\textcopyright} 2020. Published by Elsevier Inc.",
year = "2020",
doi = "10.1016/j.jacc.2020.05.077",
language = "English",
volume = "76",
pages = "844--857",
journal = "Journal of the American College of Cardiology",
issn = "0735-1097",
publisher = "Elsevier",
number = "7",

}

RIS

TY - JOUR

T1 - Saturated fats and health: A reassessment and proposal for food-based recommendations

T2 - JACC State-of-the-Art Review

AU - Astrup, Arne

AU - Magkos, Faidon

AU - Bier, Dennis M

AU - Brenna, J Thomas

AU - de Oliveira Otto, Marcia C

AU - Hill, James O

AU - King, Janet C

AU - Mente, Andrew

AU - Ordovas, Jose M

AU - Volek, Jeff S

AU - Yusuf, Salim

AU - Krauss, Ronald M

N1 - Copyright © 2020. Published by Elsevier Inc.

PY - 2020

Y1 - 2020

N2 - The recommendation to limit dietary saturated fatty acid (SFA) intake has persisted despite mounting evidence to the contrary. Most recent meta-analyses of randomized trials and observational studies found no beneficial effects of reducing SFA intake on cardiovascular disease (CVD) and total mortality, and instead found protective effects against stroke. Although SFAs increase low-density lipoprotein (LDL)-cholesterol, in most individuals, this is not due to increasing levels of small, dense LDL particles, but rather larger LDL which are much less strongly related to CVD risk. It is also apparent that the health effects of foods cannot be predicted by their content in any nutrient group, without considering the overall macronutrient distribution. Whole-fat dairy, unprocessed meat, eggs and dark chocolate are SFA-rich foods with a complex matrix that are not associated with increased risk of CVD. The totality of available evidence does not support further limiting the intake of such foods.

AB - The recommendation to limit dietary saturated fatty acid (SFA) intake has persisted despite mounting evidence to the contrary. Most recent meta-analyses of randomized trials and observational studies found no beneficial effects of reducing SFA intake on cardiovascular disease (CVD) and total mortality, and instead found protective effects against stroke. Although SFAs increase low-density lipoprotein (LDL)-cholesterol, in most individuals, this is not due to increasing levels of small, dense LDL particles, but rather larger LDL which are much less strongly related to CVD risk. It is also apparent that the health effects of foods cannot be predicted by their content in any nutrient group, without considering the overall macronutrient distribution. Whole-fat dairy, unprocessed meat, eggs and dark chocolate are SFA-rich foods with a complex matrix that are not associated with increased risk of CVD. The totality of available evidence does not support further limiting the intake of such foods.

KW - Faculty of Science

KW - Cardiovascular disease

KW - Diet

KW - Saturated fat

KW - Food matrix

U2 - 10.1016/j.jacc.2020.05.077

DO - 10.1016/j.jacc.2020.05.077

M3 - Review

C2 - 32562735

VL - 76

SP - 844

EP - 857

JO - Journal of the American College of Cardiology

JF - Journal of the American College of Cardiology

SN - 0735-1097

IS - 7

ER -

ID: 243343145