Engineering Barriers to Infection by Undermining Pathogen Effector Function or by Gaining Effector Recognition

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

Standard

Engineering Barriers to Infection by Undermining Pathogen Effector Function or by Gaining Effector Recognition. / Ahmed, Ali Abdurehim; Mclellan, Hazel; Aguilar, Geziel Barbosa; Hein, Ingo; Thordal-Christensen, Hans; Birch, Paul R.J.

Plant Pathogen Resistance Biotechnology. ed. / David B. Collinge. Wiley-Blackwell, 2016. p. 23-50.

Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

Harvard

Ahmed, AA, Mclellan, H, Aguilar, GB, Hein, I, Thordal-Christensen, H & Birch, PRJ 2016, Engineering Barriers to Infection by Undermining Pathogen Effector Function or by Gaining Effector Recognition. in DB Collinge (ed.), Plant Pathogen Resistance Biotechnology. Wiley-Blackwell, pp. 23-50. https://doi.org/10.1002/9781118867716.ch2

APA

Ahmed, A. A., Mclellan, H., Aguilar, G. B., Hein, I., Thordal-Christensen, H., & Birch, P. R. J. (2016). Engineering Barriers to Infection by Undermining Pathogen Effector Function or by Gaining Effector Recognition. In D. B. Collinge (Ed.), Plant Pathogen Resistance Biotechnology (pp. 23-50). Wiley-Blackwell. https://doi.org/10.1002/9781118867716.ch2

Vancouver

Ahmed AA, Mclellan H, Aguilar GB, Hein I, Thordal-Christensen H, Birch PRJ. Engineering Barriers to Infection by Undermining Pathogen Effector Function or by Gaining Effector Recognition. In Collinge DB, editor, Plant Pathogen Resistance Biotechnology. Wiley-Blackwell. 2016. p. 23-50 https://doi.org/10.1002/9781118867716.ch2

Author

Ahmed, Ali Abdurehim ; Mclellan, Hazel ; Aguilar, Geziel Barbosa ; Hein, Ingo ; Thordal-Christensen, Hans ; Birch, Paul R.J. / Engineering Barriers to Infection by Undermining Pathogen Effector Function or by Gaining Effector Recognition. Plant Pathogen Resistance Biotechnology. editor / David B. Collinge. Wiley-Blackwell, 2016. pp. 23-50

Bibtex

@inbook{6d3dfa3dd5a443c48658a7e15d9a4765,
title = "Engineering Barriers to Infection by Undermining Pathogen Effector Function or by Gaining Effector Recognition",
abstract = "This chapter reviews potential disease control strategies by employing the current understanding of Pathogen-Associated Molecular Patterns (PAMPs) and their receptors, as well as effectors and their targets. It discusses how effectoromics, i.e. surveying which, and to what level, effectors are expressed at a pathogen population level, can help to select the most useful and durable R genes. Plant immunity can be boosted by overexpressing a Pattern-Recognition Receptor (PRR) in a closely- or more-distantly related plant to strengthen PAMP-Triggered Immunity (PTI). An interesting aspect of NB-LRR transcript regulation that involves small RNAs is currently emerging and could potentially be explored in the search for more durable and/or broad-spectrum pathogen resistance. The chapter suggests ways that can be used to undermine effector function and be exploited to engineer resistant plants in the future. It further illustrates how a mechanistic understanding of a pathogen's stealth strategies may allow new approaches to engineer resistance.",
keywords = "Effector recognition, Effectoromics, Engineering resistance, NB-LRR-type resistance proteins, PAMP-triggered immunity, Pathogen effector function, Pattern recognition receptor, Plant defence",
author = "Ahmed, {Ali Abdurehim} and Hazel Mclellan and Aguilar, {Geziel Barbosa} and Ingo Hein and Hans Thordal-Christensen and Birch, {Paul R.J.}",
year = "2016",
doi = "10.1002/9781118867716.ch2",
language = "English",
isbn = "9781118867761",
pages = "23--50",
editor = "Collinge, {David B.}",
booktitle = "Plant Pathogen Resistance Biotechnology",
publisher = "Wiley-Blackwell",
address = "United Kingdom",

}

RIS

TY - CHAP

T1 - Engineering Barriers to Infection by Undermining Pathogen Effector Function or by Gaining Effector Recognition

AU - Ahmed, Ali Abdurehim

AU - Mclellan, Hazel

AU - Aguilar, Geziel Barbosa

AU - Hein, Ingo

AU - Thordal-Christensen, Hans

AU - Birch, Paul R.J.

PY - 2016

Y1 - 2016

N2 - This chapter reviews potential disease control strategies by employing the current understanding of Pathogen-Associated Molecular Patterns (PAMPs) and their receptors, as well as effectors and their targets. It discusses how effectoromics, i.e. surveying which, and to what level, effectors are expressed at a pathogen population level, can help to select the most useful and durable R genes. Plant immunity can be boosted by overexpressing a Pattern-Recognition Receptor (PRR) in a closely- or more-distantly related plant to strengthen PAMP-Triggered Immunity (PTI). An interesting aspect of NB-LRR transcript regulation that involves small RNAs is currently emerging and could potentially be explored in the search for more durable and/or broad-spectrum pathogen resistance. The chapter suggests ways that can be used to undermine effector function and be exploited to engineer resistant plants in the future. It further illustrates how a mechanistic understanding of a pathogen's stealth strategies may allow new approaches to engineer resistance.

AB - This chapter reviews potential disease control strategies by employing the current understanding of Pathogen-Associated Molecular Patterns (PAMPs) and their receptors, as well as effectors and their targets. It discusses how effectoromics, i.e. surveying which, and to what level, effectors are expressed at a pathogen population level, can help to select the most useful and durable R genes. Plant immunity can be boosted by overexpressing a Pattern-Recognition Receptor (PRR) in a closely- or more-distantly related plant to strengthen PAMP-Triggered Immunity (PTI). An interesting aspect of NB-LRR transcript regulation that involves small RNAs is currently emerging and could potentially be explored in the search for more durable and/or broad-spectrum pathogen resistance. The chapter suggests ways that can be used to undermine effector function and be exploited to engineer resistant plants in the future. It further illustrates how a mechanistic understanding of a pathogen's stealth strategies may allow new approaches to engineer resistance.

KW - Effector recognition

KW - Effectoromics

KW - Engineering resistance

KW - NB-LRR-type resistance proteins

KW - PAMP-triggered immunity

KW - Pathogen effector function

KW - Pattern recognition receptor

KW - Plant defence

U2 - 10.1002/9781118867716.ch2

DO - 10.1002/9781118867716.ch2

M3 - Book chapter

AN - SCOPUS:85017660801

SN - 9781118867761

SP - 23

EP - 50

BT - Plant Pathogen Resistance Biotechnology

A2 - Collinge, David B.

PB - Wiley-Blackwell

ER -

ID: 178847110