Independent control of replication initiation of the two Vibrio cholerae chromosomes by DnaA and RctB
Research output: Contribution to journal › Journal article › Research › peer-review
Although the two Vibrio cholerae chromosomes initiate replication in a coordinated fashion, we show here that each chromosome appears to have a specific replication initiator. DnaA overproduction promoted overinitiation of chromosome I and not chromosome II. In contrast, overproduction of RctB, a protein that binds to the origin of replication of chromosome II, promoted overinitiation of chromosome II and not chromosome I.
| Original language | English |
|---|---|
| Journal | Journal of Bacteriology |
| Volume | 188 |
| Issue number | 17 |
| Pages (from-to) | 6419-6424 |
| Number of pages | 6 |
| ISSN | 0021-9193 |
| DOIs | |
| Publication status | Published - 2006 |
| Externally published | Yes |
- Bacterial Proteins/physiology, Chromosomes, Bacterial/genetics, DNA Replication, DNA-Binding Proteins/physiology, Vibrio cholerae/genetics
Research areas
ID: 200971864