Søren Bak

Søren Bak

Professor

Member of:

    ORCID: 0000-0003-4100-115X

    Introductory remarks on publicationslist

    ResearcherID H-4404-2014

    ORCID 0000-0003-4100-115X


    Publication year:
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    1 - 50 out of 227Page size: 50
    1. 2024
    2. E-pub ahead of print

      Site-directed genotype screening for elimination of antinutritional saponins in quinoa seeds identifies TSARL1 as a master controller of saponin biosynthesis selectively in seeds

      Trinh, Mai Duy Luu, Visintainer, Davide, Günther, Jan, Østerberg, J. T., Rodrigues da Fonseca, Rute Andreia, Fondevilla, S., Moog, Max William, Luo, Guangbin, Nørrevang, Anton Frisgaard, Crocoll, C., Nielsen, P. V., Jacobsen, S., Wendt, T., Bak, Søren, Lopez Marques, Rosa Laura & Palmgren, Michael, 2024, (E-pub ahead of print) In: Plant Biotechnology Journal. 19 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    3. 2023
    4. Published

      Lessons learned from metabolic engineering in hairy roots: Transcriptome and metabolic profile changes caused by Rhizobium-mediated plant transformation in Cucurbitaceae species

      Almeida, A., Favero, Bruno Trevenzoli, Dong, L., Cárdenas, Pablo D., Saenz-Mata, J., Lütken, Henrik Vlk & Bak, Søren, Aug 2023, In: Plant Physiology and Biochemistry. 201, 8 p., 107797.

      Research output: Contribution to journal › Journal article › Research › peer-review

    5. Published

      Biosynthesis and biotechnological production of the anti-obesity agent celastrol

      Zhao, Yong, Hansen, N. L., Duan, Yaotao, Prasad, M., Motawie, Mohammed Saddik, Møller, Birger Lindberg, Pateraki, Irini, Stærk, Dan, Bak, Søren, Miettinen, Karel & Kampranis, Sotirios, 2023, In: Nature Chemistry. 15, p. 1236–1246

      Research output: Contribution to journal › Journal article › Research › peer-review

    6. Published

      Phytoalexins of the crucifer Barbarea vulgaris: Structural profile and correlation with glucosinolate turnover

      Cárdenas, Pablo D., Landtved, J. P., Larsen, S. H., Lindegaard, Nicolai, Wøhlk, S., Jensen, Karen Rysbjerg, Pattison, David, Burow, Meike, Bak, Søren, Crocoll, C. & Agerbirk, Niels, 2023, In: Phytochemistry. 213, 17 p., 113742.

      Research output: Contribution to journal › Journal article › Research › peer-review

    7. Published

      Pollen-feeding delays reproductive senescence and maintains toxicity of Heliconius erato

      Castro, E. C. P. D., McPherson, J., Jullian, G., Mattila, A. L. K., Bak, Søren, Montgomery, S. H. & Jiggins, C., 2023, bioRxiv, 18 p.

      Research output: Working paper › Preprint › Research

    8. Published

      The saponin bomb: a nucleolar-localized β-glucosidase hydrolyzes triterpene saponins in Medicago truncatula

      Lacchini, E., Erffelinck, M., Mertens, J., Marcou, S., Molina-Hidalgo, F. J., Tzfadia, O., Venegas-Molina, J., Cárdenas, Pablo D., Pollier, J., Tava, A., Bak, Søren, Höfte, M. & Goossens, A., 2023, In: New Phytologist. 239, 2, 15 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    9. 2022
    10. Published

      A GPCR-based yeast biosensor for biomedical, biotechnological, and point-of-use cannabinoid determination

      Miettinen, Karel, Leelahakorn, Nattawat, Almeida Robles, A. R., Zhao, Yong, Hansen, L. R., Nikolajsen, I. E., Andersen, Jens Bo, Givskov, Michael, Stærk, Dan, Bak, Søren & Kampranis, Sotirios, 2022, In: Nature Communications. 13, 16 p., 3664.

      Research output: Contribution to journal › Journal article › Research › peer-review

    11. Published

      Metabolic engineering of cucurbitacins in Cucurbita pepo hairy roots

      Almeida, A., Dong, L., Thorsen, T. H., Raadam, Morten Hessellund, Khakimov, Bekzod, Carreno-Quintero, N., Kampranis, Sotirios & Bak, Søren, 2022, In: Frontiers in Plant Science. 13, 18 p., 1021907.

      Research output: Contribution to journal › Journal article › Research › peer-review

    12. Published

      Reciprocal mutations of two multifunctional β-amyrin synthases from Barbarea vulgaris shift α/β-amyrin ratios

      Günther, Jan, Erthmann, P. O., Khakimov, Bekzod & Bak, Søren, 2022, In: Plant Physiology. 188, 3, p. 1483-1495

      Research output: Contribution to journal › Journal article › Research › peer-review

    13. Published

      The saponin bomb

      Erffelinck, M., Mertens, J., Lacchini, E., Molina-Hidalgo, F. J., Tzfadia, O., Cárdenas, Pablo D., Pollier, J., Tava, A., Bak, Søren & Goossens, A., 2022, Research Square, 33 p.

      Research output: Working paper › Preprint › Research

    14. 2021
    15. Published

      An independent evolutionary origin for insect deterrent cucurbitacins in Iberis amara

      Dong, L., Almeida Robles, A. R., Pollier, J., Khakimov, Bekzod, Bassard, J. A., Miettinen, K., Stærk, Dan, Mehran, R., Olsen, C. E., Motawie, Mohammed Saddik, Goossens, A. & Bak, Søren, 2021, In: Molecular Biology and Evolution. 38, 11, p. 4659-4673 15 p., msab213.

      Research output: Contribution to journal › Journal article › Research › peer-review

    16. Published

      Cascading effects of root microbial symbiosis on the development and metabolome of the insect herbivore Manduca sexta L.

      Papantoniou, D., Vergara, F., Weinhold, A., Quijano, T., Khakimov, Bekzod, Pattison, David, Bak, Søren, van Dam, N. M. & Martínez-Medina, A., 2021, In: Metabolites. 11, 11, 23 p., 731.

      Research output: Contribution to journal › Review › Research › peer-review

    17. Published

      Effects of a saponin-based insect resistance and a systemic pathogen resistance on field performance of the wild crucifer Barbarea vulgaris

      Hauser, T. P., Christensen, S., Kuzina, V., Thines, M., Ploch, S. & Bak, Søren, 2021, In: Arthropod-Plant Interactions. 15, p. 683-698

      Research output: Contribution to journal › Journal article › Research › peer-review

    18. Published

      Phenotypic plasticity in chemical defence of butterflies allows usage of diverse host plants

      De Castro, É. C. P., Musgrove, J., Bak, Søren, McMillan, W. O. & Jiggins, C. D., 2021, In: Biology Letters. 17, 3, 6 p., 20200863.

      Research output: Contribution to journal › Journal article › Research › peer-review

    19. 2020
    20. Published

      The dynamics of cyanide defences in the life cycle of an aposematic butterfly: Biosynthesis versus sequestration

      Pinheiro de Castro, É. C., Demirtas, R., Orteu, A., Olsen, C. E., Motawie, Mohammed Saddik, Zikan Cardoso, M., Zagrobelny, M. & Bak, Søren, Jan 2020, In: Insect Biochemistry and Molecular Biology. 116, p. 1-9 103259.

      Research output: Contribution to journal › Journal article › Research › peer-review

    21. Published

      Integrating pathway elucidation with yeast engineering to produce polpunonic acid the precursor of the anti-obesity agent celastrol

      Hansen, N. L., Miettinen, Karel, Zhao, Yong, Ignea, C., Andreadeli, A., Raadam, Morten Hessellund, Makris, A. M., Møller, Birger Lindberg, Stærk, Dan, Bak, Søren & Kampranis, Sotirios, 2020, In: Microbial Cell Factories. 19, 17 p., 15.

      Research output: Contribution to journal › Journal article › Research › peer-review

    22. Published

      Phenotypic plasticity in chemical defence allows butterflies to diversify host use strategies

      Castro, É. C. P. D., Musgrove, J., Bak, Søren, McMillan, W. O. & Jiggins, C. D., 2020, bioRxiv, 14 p.

      Research output: Working paper › Preprint › Research

    23. Published

      Plant triterpenoids with bond-missing skeletons: biogenesis, distribution and bioactivity

      Almeida, A., Dong, L., Appendino, G. & Bak, Søren, 2020, In: Natural Product Reports. 37, 22 p.

      Research output: Contribution to journal › Review › Research › peer-review

    24. Published

      Variation of chemical compounds in wild Heliconiini reveals ecological factors involved in the evolution of chemical defenses in mimetic butterflies

      Sculfort, O., de Castro, E. C. P., Kozak, K. M., Bak, Søren, Elias, M., Nay, B. & Llaurens, V., 2020, In: Ecology and Evolution. 10, 5, p. 2677-2694 18 p.

      Research output: Contribution to journal › Review › Research › peer-review

    25. 2019
    26. Published

      Sequestration and biosynthesis of cyanogenic glucosides in passion vine butterflies and consequences for the diversification of their host plants

      Pinheiro de Castro, É. C., Zagrobelny, M., Zurano, J. P., Zikan Cardoso, M., Feyereisen, R. & Bak, Søren, 1 May 2019, In: Ecology and Evolution. 9, 9, p. 5079-5093

      Research output: Contribution to journal › Journal article › Research › peer-review

    27. Published

      The cytochrome P450 CYP72A552 is key to production of hederagenin‐based saponins that mediate plant defense against herbivores

      Liu, Q., Khakimov, Bekzod, Cárdenas, Pablo D., Cozzi, F., Olsen, C. E., Jensen, Karen Rysbjerg, Hauser, T. P. & Bak, Søren, May 2019, In: New Phytologist (Online). 222, 3, p. 1599-1609

      Research output: Contribution to journal › Journal article › Research › peer-review

    28. Published

      Evolution of Structural Diversity of Triterpenoids

      Cárdenas, Pablo D., Almeida, A. & Bak, Søren, 2019, In: Frontiers in Plant Science. 10, p. 1-10 1523.

      Research output: Contribution to journal › Journal article › Research › peer-review

    29. Published

      Sequestration and functional diversification of cyanogenic glucosides in the life cycle of Heliconius melpomene

      Castro, É. C. P. D., Demirtas, R., Orteu, A., Olsen, C. E., Motawie, Mohammed Saddik, Cardoso, M. Z., Zagrobelny, M. & Bak, Søren, 2019, bioRxiv, 31 p.

      Research output: Working paper › Preprint › Research

    30. 2018
    31. Published

      A Single Oxidosqualene Cyclase Produces the Seco-Triterpenoid α-Onocerin

      Almeida, A., Dong, L., Khakimov, Bekzod, Bassard, J. A., Moses, T., Lota, F., Goossens, A., Appendino, G. & Bak, Søren, 2018, In: Plant Physiology. 176, 2, p. 1469-1484 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    32. Published

      A tandem array of UDP-glycosyltransferases from the UGT73C subfamily glycosylate sapogenins, forming a spectrum of mono- and bisdesmosidic saponins

      Erthmann, P. Ø., Agerbirk, Niels & Bak, Søren, 2018, In: Plant Molecular Biology. 97, 1-2, p. 37-55 19 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    33. Published

      Co-expression of squalene epoxidases with triterpene cyclases boosts production of triterpenoids in plants and yeast

      Dong, L., Pollier, J., Bassard, J., Ntallas, G., Almeida, A., Lazaridi, E., Khakimov, Bekzod, Arendt, P., de Oliveira, L. S., Lota, F., Goossens, A., Michoux, F. & Bak, Søren, 2018, In: Metabolic Engineering. 49, p. 1-12

      Research output: Contribution to journal › Journal article › Research › peer-review

    34. Published

      Cyanogenesis in arthropods: from chemical warfare to nuptial gifts

      Zagrobelny, M., Pinheiro de Castro, É. C., Møller, Birger Lindberg & Bak, Søren, 2018, In: Insects. 9, 2, 39 p., 51.

      Research output: Contribution to journal › Review › Research › peer-review

    35. Published

      Evolution of the biosynthetic pathway for cyanogenic glucosides in Lepidoptera

      Zagrobelny, M., Jensen, M. K., Vogel, H., Feyereisen, R. & Bak, Søren, 2018, In: Journal of Molecular Evolution. 86, 6, p. 379-394 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    36. Published

      Glucosinolate turnover in Brassicales species to an oxazolidin-2-one, formed via the 2-thione and without formation of thioamide

      Agerbirk, Niels, Matthes, A., Erthmann, P. Ø., Ugolini, L., Cinti, S., Lazaridi, E., Nuzillard, J., Mueller, C., Bak, Søren, Rollin, P. & Lazzeri, L., 2018, In: Phytochemistry. 153, p. 79-93

      Research output: Contribution to journal › Journal article › Research › peer-review

    37. Published

      The TriForC database: a comprehensive up-to-date resource of plant triterpene biosynthesis

      Miettinen, Karel, Inigo, S., Kreft, L., Pollier, J., De Bo, C., Botzki, A., Coppens, F., Bak, Søren & Goossens, A., 2018, In: Nucleic Acids Research. 46, D1, p. D586-D594 9 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    38. Published

      The arms race between heliconiine butterflies and Passiflora plants - new insights on an ancient subject

      Pinheiro de Castro, É. C., Zagrobelny, M., Cardoso, M. Z. & Bak, Søren, 2018, In: Biological Reviews. 93, 1, p. 555-573 19 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    39. Published

      Triterpene Messages from the EU-FP7 Project TriForC

      Goossens, A., Osbourn, A., Michoux, F. & Bak, Søren, 2018, In: Trends in Plant Science. 23, 4, p. 273-276

      Research output: Contribution to journal › Editorial › Research › peer-review

    40. 2017
    41. Published

      Developmentally regulated glucosylation of bitter triterpenoid in cucumber by the Udp-Glucosyltransferase Ugt73am3

      Zhong, Y., Xue, X., Liu, Z., Ma, Y., Zeng, K., Han, L., Qi, J., Ro, D., Bak, Søren, Huang, S., Zhou, Y. & Shang, Y., 2017, In: Molecular Plant. 10, 7, p. 1000-1003 4 p.

      Research output: Contribution to journal › Letter › Research › peer-review

    42. Published

      Quinoa seed coats as an expanding and sustainable source of bioactive compounds: an investigation of genotypic diversity in saponin profiles

      Ruiz, K. B., Khakimov, Bekzod, Engelsen, Søren Balling, Bak, Søren, Biondi, S. & Jacobsen, S., 2017, In: Industrial Crops and Products. 104, p. 156-163 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    43. Published

      Spatial separation of the cyanogenic β-glucosidase ZfBGD2 and cyanogenic glucosides in the haemolymph of Zygaena larvae facilitates cyanide release

      Pentzold, S., Jensen, M. K., Matthes, A., Olsen, C. E., Petersen, Bent L, Clausen, Henrik, Møller, Birger Lindberg, Bak, Søren & Zagrobelny, M., 2017, In: Royal Society Open Science. 4, 13 p., 170262.

      Research output: Contribution to journal › Journal article › Research › peer-review

    44. Published

      The genome sequence of Barbarea vulgaris facilitates the study of ecological biochemistry

      Byrne, S. L., Erthmann, P. Ø., Agerbirk, Niels, Bak, Søren, Hauser, T. P., Nagy, I., Paina, C. & Asp, T., 2017, In: Scientific Reports. 7, 14 p., 40728.

      Research output: Contribution to journal › Journal article › Research › peer-review

    45. 2016
    46. Published

      Lepidopteran defence droplets - a composite physical and chemical weapon against potential predators

      Pentzold, S., Zagrobelny, M., Khakimov, Bekzod, Engelsen, Søren Balling, Clausen, Henrik, Petersen, Bent L, Borch, J., Møller, Birger Lindberg & Bak, Søren, 2016, In: Scientific Reports. 6, 11 p., 22407 .

      Research output: Contribution to journal › Journal article › Research › peer-review

    47. Published

      Screening for triterpenoid saponins in plants using hyphenated analytical platforms

      Khakimov, Bekzod, Tseng, L. H., Godejohann, M., Bak, Søren & Engelsen, Søren Balling, 2016, In: Molecules. 21, 12, 19 p., 1614.

      Research output: Contribution to journal › Journal article › Research › peer-review

    48. 2015
    49. Published

      Identification and genome organization of saponin pathway genes from a wild crucifer, and their use for transient production of saponins in Nicotiana benthamiana

      Khakimov, Bekzod, Poulsen, V. K., Erthmann, P. Ø., Fukushima, E. O., Augustin, J. M., Olsen, C. E., Scholtalbers, J., Volpin, H., Andersen, S. B., Hauser, T. P., Muranaka, T. & Bak, Søren, 2015, In: The Plant Journal. 84, 3, p. 478-490 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    50. Published

      Metabolism, excretion and avoidance of cyanogenic glucosides in insects with different feeding specialisations

      Pentzold, S., Zagrobelny, M., Bjarnholt, Nanna, Kroymann, J., Vogel, H., Olsen, C. E., Møller, Birger Lindberg & Bak, Søren, 2015, In: Insect Biochemistry and Molecular Biology. 66, p. 119-128 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    51. Published

      Multiple hydroxyphenethyl glucosinolate isomers and their tandem mass spectrometric destinction in a geographically structured polymorphism in the crucifer Barbarea vulgaris

      Agerbirk, Niels, Olsen, C. E., Heimes, C., Christensen, S., Bak, Søren & Hauser, T. P., 2015, In: Phytochemistry. 115, p. 130-142 13 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    52. Published

      The bifurcation of the cyanogenic glucoside and glucosinolate biosynthetic pathways

      Sørensen, Mette, Kannangara, R. M., Olsen, C. E., Blomstedt, C. K., Gleadow, R. M., Jørgensen, Kirsten, Bak, Søren, Motawie, Mohammed Saddik & Møller, Birger Lindberg, 2015, In: The Plant Journal. 84, 3, p. 558-573 16 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    53. Published

      Volatiles from the burnet Moth Zygaena filipendulae (Lepidoptera) and Associated flowers, and their involvement in mating communication

      Zagrobelny, M., Simonsen, H. T., Olsen, C. E., Bak, Søren & Møller, Birger Lindberg, 2015, In: Physiological Entomology. 40, 4, p. 284-295 12 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    54. 2014
    55. Published

      Chemical defense balanced by sequestration and de novo biosynthesis in a lepidopteran specialist

      Fürstenberg-Hägg, J., Zagrobelny, M., Jørgensen, Kirsten, Vogel, H., Møller, Birger Lindberg & Bak, Søren, 2014, In: P L o S One. 9, 10, 9 p., e108745.

      Research output: Contribution to journal › Journal article › Research › peer-review

    56. Published

      High-throughput cereal metabolomics: current analytical technologies, challenges and perspectives

      Khakimov, Bekzod, Bak, Søren & Engelsen, Søren Balling, 2014, In: Journal of Cereal Science. 59, 3, p. 393-418 26 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    57. Published

      How insects overcome two-component plant chemical defence: plant β-glucosidases as the main target for herbivore adaptation

      Pentzold, S., Zagrobelny, M., Rook, F. & Bak, Søren, 2014, In: Biological Reviews. 89, 3, p. 531-551 21 p.

      Research output: Contribution to journal › Review › Research › peer-review

    58. Published

      Sequestration, tissue distribution and developmental transmission of cyanogenic glucosides in a specialist insect herbivore

      Zagrobelny, M., Olsen, C. E., Pentzold, S., Fürstenberg-Hägg, J., Jørgensen, Kirsten, Bak, Søren, Møller, Birger Lindberg & Motawie, Mohammed Saddik, 2014, In: Insect Biochemistry and Molecular Biology. 44, p. 44-53 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    59. Published

      The multiple strategies of an insect herbivore to overcome plant cyanogenic glucoside defence

      Pentzold, S., Zagrobelny, M., Roelsgaard, P. S., Møller, Birger Lindberg & Bak, Søren, 2014, In: PLOS ONE. 9, 3, 8 p., e91337.

      Research output: Contribution to journal › Journal article › Research › peer-review

    60. Published

      Transcriptional regulation of de novo biosynthesis of cyanogenic glucosides throughout the life-cycle of the burnet moth Zyagena filipendulae (Lepidoptera)

      Fürstenberg-Hägg, J., Zagrobelny, M., Olsen, C. E., Jørgensen, Kirsten, Møller, Birger Lindberg & Bak, Søren, 2014, In: Insect Biochemistry and Molecular Biology. 49, p. 80-89 10 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

    61. 2013
    62. Published

      Biochemical analysis of a multifunctional cytochrome P450 (CYP51) enzyme required for synthesis of antimicrobial triterpenes in plants

      Geisler, K., Hughes, R. K., Sainsbury, F., Lomonossoff, G. P., Rejzek, M., Fairhurst, S., Olsen, C. E., Motawie, Mohammed Saddik, Melton, R. E., Hemmings, A. M., Bak, Søren & Osbourn, A., 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 35, p. E3360-E3367 8 p.

      Research output: Contribution to journal › Journal article › Research › peer-review

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