Søren Bak

Søren Bak

Professor

Introductory remarks on publicationslist

ResearcherID H-4404-2014

ORCID 0000-0003-4100-115X


  1. 2024
  2. E-pub ahead of print

    Site-directed genotype screening for elimination of antinutritional saponins in quinoa seeds identifies TSARL1 as a master controller of saponin biosynthesis selectively in seeds

    Trinh, Mai Duy Luu, Visintainer, Davide, Günther, Jan, Østerberg, J. T., Rodrigues da Fonseca, Rute Andreia, Fondevilla, S., Moog, Max William, Luo, Guangbin, Nørrevang, Anton Frisgaard, Crocoll, C., Nielsen, P. V., Jacobsen, S., Wendt, T., Bak, Søren, Lopez Marques, Rosa Laura & Palmgren, Michael, 2024, (E-pub ahead of print) In: Plant Biotechnology Journal. 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  3. 2023
  4. Published

    Lessons learned from metabolic engineering in hairy roots: Transcriptome and metabolic profile changes caused by Rhizobium-mediated plant transformation in Cucurbitaceae species

    Almeida, A., Favero, Bruno Trevenzoli, Dong, L., Cárdenas, Pablo D., Saenz-Mata, J., Lütken, Henrik Vlk & Bak, Søren, Aug 2023, In: Plant Physiology and Biochemistry. 201, 8 p., 107797.

    Research output: Contribution to journalJournal articleResearchpeer-review

  5. Published

    Biosynthesis and biotechnological production of the anti-obesity agent celastrol

    Zhao, Yong, Hansen, N. L., Duan, Yaotao, Prasad, M., Motawie, Mohammed Saddik, Møller, Birger Lindberg, Pateraki, Irini, Stærk, Dan, Bak, Søren, Miettinen, Karel & Kampranis, Sotirios, 2023, In: Nature Chemistry. 15, p. 1236–1246

    Research output: Contribution to journalJournal articleResearchpeer-review

  6. Published

    Phytoalexins of the crucifer Barbarea vulgaris: Structural profile and correlation with glucosinolate turnover

    Cárdenas, Pablo D., Landtved, J. P., Larsen, S. H., Lindegaard, Nicolai, Wøhlk, S., Jensen, Karen Rysbjerg, Pattison, David, Burow, Meike, Bak, Søren, Crocoll, C. & Agerbirk, Niels, 2023, In: Phytochemistry. 213, 17 p., 113742.

    Research output: Contribution to journalJournal articleResearchpeer-review

  7. Published

    Pollen-feeding delays reproductive senescence and maintains toxicity of Heliconius erato

    Castro, E. C. P. D., McPherson, J., Jullian, G., Mattila, A. L. K., Bak, Søren, Montgomery, S. H. & Jiggins, C., 2023, bioRxiv, 18 p.

    Research output: Working paperPreprintResearch

  8. Published

    The saponin bomb: a nucleolar-localized β-glucosidase hydrolyzes triterpene saponins in Medicago truncatula

    Lacchini, E., Erffelinck, M., Mertens, J., Marcou, S., Molina-Hidalgo, F. J., Tzfadia, O., Venegas-Molina, J., Cárdenas, Pablo D., Pollier, J., Tava, A., Bak, Søren, Höfte, M. & Goossens, A., 2023, In: New Phytologist. 239, 2, 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  9. 2022
  10. Published

    A GPCR-based yeast biosensor for biomedical, biotechnological, and point-of-use cannabinoid determination

    Miettinen, Karel, Leelahakorn, Nattawat, Almeida Robles, A. R., Zhao, Yong, Hansen, L. R., Nikolajsen, I. E., Andersen, Jens Bo, Givskov, Michael, Stærk, Dan, Bak, Søren & Kampranis, Sotirios, 2022, In: Nature Communications. 13, 16 p., 3664.

    Research output: Contribution to journalJournal articleResearchpeer-review

  11. Published

    Metabolic engineering of cucurbitacins in Cucurbita pepo hairy roots

    Almeida, A., Dong, L., Thorsen, T. H., Raadam, Morten Hessellund, Khakimov, Bekzod, Carreno-Quintero, N., Kampranis, Sotirios & Bak, Søren, 2022, In: Frontiers in Plant Science. 13, 18 p., 1021907.

    Research output: Contribution to journalJournal articleResearchpeer-review

  12. Published

    Reciprocal mutations of two multifunctional β-amyrin synthases from Barbarea vulgaris shift α/β-amyrin ratios

    Günther, Jan, Erthmann, P. O., Khakimov, Bekzod & Bak, Søren, 2022, In: Plant Physiology. 188, 3, p. 1483-1495

    Research output: Contribution to journalJournal articleResearchpeer-review

  13. Published

    The saponin bomb

    Erffelinck, M., Mertens, J., Lacchini, E., Molina-Hidalgo, F. J., Tzfadia, O., Cárdenas, Pablo D., Pollier, J., Tava, A., Bak, Søren & Goossens, A., 2022, Research Square, 33 p.

    Research output: Working paperPreprintResearch

  14. 2021
  15. Published

    An independent evolutionary origin for insect deterrent cucurbitacins in Iberis amara

    Dong, L., Almeida Robles, A. R., Pollier, J., Khakimov, Bekzod, Bassard, J. A., Miettinen, K., Stærk, Dan, Mehran, R., Olsen, C. E., Motawie, Mohammed Saddik, Goossens, A. & Bak, Søren, 2021, In: Molecular Biology and Evolution. 38, 11, p. 4659-4673 15 p., msab213.

    Research output: Contribution to journalJournal articleResearchpeer-review

  16. Published

    Cascading effects of root microbial symbiosis on the development and metabolome of the insect herbivore Manduca sexta L.

    Papantoniou, D., Vergara, F., Weinhold, A., Quijano, T., Khakimov, Bekzod, Pattison, David, Bak, Søren, van Dam, N. M. & Martínez-Medina, A., 2021, In: Metabolites. 11, 11, 23 p., 731.

    Research output: Contribution to journalReviewResearchpeer-review

  17. Published

    Effects of a saponin-based insect resistance and a systemic pathogen resistance on field performance of the wild crucifer Barbarea vulgaris

    Hauser, T. P., Christensen, S., Kuzina, V., Thines, M., Ploch, S. & Bak, Søren, 2021, In: Arthropod-Plant Interactions. 15, p. 683-698

    Research output: Contribution to journalJournal articleResearchpeer-review

  18. Published

    Phenotypic plasticity in chemical defence of butterflies allows usage of diverse host plants

    De Castro, É. C. P., Musgrove, J., Bak, Søren, McMillan, W. O. & Jiggins, C. D., 2021, In: Biology Letters. 17, 3, 6 p., 20200863.

    Research output: Contribution to journalJournal articleResearchpeer-review

  19. 2020
  20. Published

    The dynamics of cyanide defences in the life cycle of an aposematic butterfly: Biosynthesis versus sequestration

    Pinheiro de Castro, É. C., Demirtas, R., Orteu, A., Olsen, C. E., Motawie, Mohammed Saddik, Zikan Cardoso, M., Zagrobelny, M. & Bak, Søren, Jan 2020, In: Insect Biochemistry and Molecular Biology. 116, p. 1-9 103259.

    Research output: Contribution to journalJournal articleResearchpeer-review

  21. Published

    Integrating pathway elucidation with yeast engineering to produce polpunonic acid the precursor of the anti-obesity agent celastrol

    Hansen, N. L., Miettinen, Karel, Zhao, Yong, Ignea, C., Andreadeli, A., Raadam, Morten Hessellund, Makris, A. M., Møller, Birger Lindberg, Stærk, Dan, Bak, Søren & Kampranis, Sotirios, 2020, In: Microbial Cell Factories. 19, 17 p., 15.

    Research output: Contribution to journalJournal articleResearchpeer-review

  22. Published

    Phenotypic plasticity in chemical defence allows butterflies to diversify host use strategies

    Castro, É. C. P. D., Musgrove, J., Bak, Søren, McMillan, W. O. & Jiggins, C. D., 2020, bioRxiv, 14 p.

    Research output: Working paperPreprintResearch

  23. Published

    Plant triterpenoids with bond-missing skeletons: biogenesis, distribution and bioactivity

    Almeida, A., Dong, L., Appendino, G. & Bak, Søren, 2020, In: Natural Product Reports. 37, 22 p.

    Research output: Contribution to journalReviewResearchpeer-review

  24. Published

    Variation of chemical compounds in wild Heliconiini reveals ecological factors involved in the evolution of chemical defenses in mimetic butterflies

    Sculfort, O., de Castro, E. C. P., Kozak, K. M., Bak, Søren, Elias, M., Nay, B. & Llaurens, V., 2020, In: Ecology and Evolution. 10, 5, p. 2677-2694 18 p.

    Research output: Contribution to journalReviewResearchpeer-review

  25. 2019
  26. Published

    Sequestration and biosynthesis of cyanogenic glucosides in passion vine butterflies and consequences for the diversification of their host plants

    Pinheiro de Castro, É. C., Zagrobelny, M., Zurano, J. P., Zikan Cardoso, M., Feyereisen, R. & Bak, Søren, 1 May 2019, In: Ecology and Evolution. 9, 9, p. 5079-5093

    Research output: Contribution to journalJournal articleResearchpeer-review

  27. Published

    The cytochrome P450 CYP72A552 is key to production of hederagenin‐based saponins that mediate plant defense against herbivores

    Liu, Q., Khakimov, Bekzod, Cárdenas, Pablo D., Cozzi, F., Olsen, C. E., Jensen, Karen Rysbjerg, Hauser, T. P. & Bak, Søren, May 2019, In: New Phytologist (Online). 222, 3, p. 1599-1609

    Research output: Contribution to journalJournal articleResearchpeer-review

  28. Published

    Evolution of Structural Diversity of Triterpenoids

    Cárdenas, Pablo D., Almeida, A. & Bak, Søren, 2019, In: Frontiers in Plant Science. 10, p. 1-10 1523.

    Research output: Contribution to journalJournal articleResearchpeer-review

  29. Published

    Sequestration and functional diversification of cyanogenic glucosides in the life cycle of Heliconius melpomene

    Castro, É. C. P. D., Demirtas, R., Orteu, A., Olsen, C. E., Motawie, Mohammed Saddik, Cardoso, M. Z., Zagrobelny, M. & Bak, Søren, 2019, bioRxiv, 31 p.

    Research output: Working paperPreprintResearch

  30. 2018
  31. Published

    A Single Oxidosqualene Cyclase Produces the Seco-Triterpenoid α-Onocerin

    Almeida, A., Dong, L., Khakimov, Bekzod, Bassard, J. A., Moses, T., Lota, F., Goossens, A., Appendino, G. & Bak, Søren, 2018, In: Plant Physiology. 176, 2, p. 1469-1484 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  32. Published

    A tandem array of UDP-glycosyltransferases from the UGT73C subfamily glycosylate sapogenins, forming a spectrum of mono- and bisdesmosidic saponins

    Erthmann, P. Ø., Agerbirk, Niels & Bak, Søren, 2018, In: Plant Molecular Biology. 97, 1-2, p. 37-55 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  33. Published

    Co-expression of squalene epoxidases with triterpene cyclases boosts production of triterpenoids in plants and yeast

    Dong, L., Pollier, J., Bassard, J., Ntallas, G., Almeida, A., Lazaridi, E., Khakimov, Bekzod, Arendt, P., de Oliveira, L. S., Lota, F., Goossens, A., Michoux, F. & Bak, Søren, 2018, In: Metabolic Engineering. 49, p. 1-12

    Research output: Contribution to journalJournal articleResearchpeer-review

  34. Published

    Cyanogenesis in arthropods: from chemical warfare to nuptial gifts

    Zagrobelny, M., Pinheiro de Castro, É. C., Møller, Birger Lindberg & Bak, Søren, 2018, In: Insects. 9, 2, 39 p., 51.

    Research output: Contribution to journalReviewResearchpeer-review

  35. Published

    Evolution of the biosynthetic pathway for cyanogenic glucosides in Lepidoptera

    Zagrobelny, M., Jensen, M. K., Vogel, H., Feyereisen, R. & Bak, Søren, 2018, In: Journal of Molecular Evolution. 86, 6, p. 379-394 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  36. Published

    Glucosinolate turnover in Brassicales species to an oxazolidin-2-one, formed via the 2-thione and without formation of thioamide

    Agerbirk, Niels, Matthes, A., Erthmann, P. Ø., Ugolini, L., Cinti, S., Lazaridi, E., Nuzillard, J., Mueller, C., Bak, Søren, Rollin, P. & Lazzeri, L., 2018, In: Phytochemistry. 153, p. 79-93

    Research output: Contribution to journalJournal articleResearchpeer-review

  37. Published

    The TriForC database: a comprehensive up-to-date resource of plant triterpene biosynthesis

    Miettinen, Karel, Inigo, S., Kreft, L., Pollier, J., De Bo, C., Botzki, A., Coppens, F., Bak, Søren & Goossens, A., 2018, In: Nucleic Acids Research. 46, D1, p. D586-D594 9 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  38. Published

    The arms race between heliconiine butterflies and Passiflora plants - new insights on an ancient subject

    Pinheiro de Castro, É. C., Zagrobelny, M., Cardoso, M. Z. & Bak, Søren, 2018, In: Biological Reviews. 93, 1, p. 555-573 19 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  39. Published

    Triterpene Messages from the EU-FP7 Project TriForC

    Goossens, A., Osbourn, A., Michoux, F. & Bak, Søren, 2018, In: Trends in Plant Science. 23, 4, p. 273-276

    Research output: Contribution to journalEditorialResearchpeer-review

  40. 2017
  41. Published

    Developmentally regulated glucosylation of bitter triterpenoid in cucumber by the Udp-Glucosyltransferase Ugt73am3

    Zhong, Y., Xue, X., Liu, Z., Ma, Y., Zeng, K., Han, L., Qi, J., Ro, D., Bak, Søren, Huang, S., Zhou, Y. & Shang, Y., 2017, In: Molecular Plant. 10, 7, p. 1000-1003 4 p.

    Research output: Contribution to journalLetterResearchpeer-review

  42. Published

    Quinoa seed coats as an expanding and sustainable source of bioactive compounds: an investigation of genotypic diversity in saponin profiles

    Ruiz, K. B., Khakimov, Bekzod, Engelsen, Søren Balling, Bak, Søren, Biondi, S. & Jacobsen, S., 2017, In: Industrial Crops and Products. 104, p. 156-163 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  43. Published

    Spatial separation of the cyanogenic β-glucosidase ZfBGD2 and cyanogenic glucosides in the haemolymph of Zygaena larvae facilitates cyanide release

    Pentzold, S., Jensen, M. K., Matthes, A., Olsen, C. E., Petersen, Bent L, Clausen, Henrik, Møller, Birger Lindberg, Bak, Søren & Zagrobelny, M., 2017, In: Royal Society Open Science. 4, 13 p., 170262.

    Research output: Contribution to journalJournal articleResearchpeer-review

  44. Published

    The genome sequence of Barbarea vulgaris facilitates the study of ecological biochemistry

    Byrne, S. L., Erthmann, P. Ø., Agerbirk, Niels, Bak, Søren, Hauser, T. P., Nagy, I., Paina, C. & Asp, T., 2017, In: Scientific Reports. 7, 14 p., 40728.

    Research output: Contribution to journalJournal articleResearchpeer-review

  45. 2016
  46. Published

    Lepidopteran defence droplets - a composite physical and chemical weapon against potential predators

    Pentzold, S., Zagrobelny, M., Khakimov, Bekzod, Engelsen, Søren Balling, Clausen, Henrik, Petersen, Bent L, Borch, J., Møller, Birger Lindberg & Bak, Søren, 2016, In: Scientific Reports. 6, 11 p., 22407 .

    Research output: Contribution to journalJournal articleResearchpeer-review

  47. Published

    Screening for triterpenoid saponins in plants using hyphenated analytical platforms

    Khakimov, Bekzod, Tseng, L. H., Godejohann, M., Bak, Søren & Engelsen, Søren Balling, 2016, In: Molecules. 21, 12, 19 p., 1614.

    Research output: Contribution to journalJournal articleResearchpeer-review

  48. 2015
  49. Published

    Identification and genome organization of saponin pathway genes from a wild crucifer, and their use for transient production of saponins in Nicotiana benthamiana

    Khakimov, Bekzod, Poulsen, V. K., Erthmann, P. Ø., Fukushima, E. O., Augustin, J. M., Olsen, C. E., Scholtalbers, J., Volpin, H., Andersen, S. B., Hauser, T. P., Muranaka, T. & Bak, Søren, 2015, In: The Plant Journal. 84, 3, p. 478-490 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  50. Published

    Metabolism, excretion and avoidance of cyanogenic glucosides in insects with different feeding specialisations

    Pentzold, S., Zagrobelny, M., Bjarnholt, Nanna, Kroymann, J., Vogel, H., Olsen, C. E., Møller, Birger Lindberg & Bak, Søren, 2015, In: Insect Biochemistry and Molecular Biology. 66, p. 119-128 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  51. Published

    Multiple hydroxyphenethyl glucosinolate isomers and their tandem mass spectrometric destinction in a geographically structured polymorphism in the crucifer Barbarea vulgaris

    Agerbirk, Niels, Olsen, C. E., Heimes, C., Christensen, S., Bak, Søren & Hauser, T. P., 2015, In: Phytochemistry. 115, p. 130-142 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  52. Published

    The bifurcation of the cyanogenic glucoside and glucosinolate biosynthetic pathways

    Sørensen, Mette, Kannangara, R. M., Olsen, C. E., Blomstedt, C. K., Gleadow, R. M., Jørgensen, Kirsten, Bak, Søren, Motawie, Mohammed Saddik & Møller, Birger Lindberg, 2015, In: The Plant Journal. 84, 3, p. 558-573 16 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  53. Published

    Volatiles from the burnet Moth Zygaena filipendulae (Lepidoptera) and Associated flowers, and their involvement in mating communication

    Zagrobelny, M., Simonsen, H. T., Olsen, C. E., Bak, Søren & Møller, Birger Lindberg, 2015, In: Physiological Entomology. 40, 4, p. 284-295 12 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  54. 2014
  55. Published

    Chemical defense balanced by sequestration and de novo biosynthesis in a lepidopteran specialist

    Fürstenberg-Hägg, J., Zagrobelny, M., Jørgensen, Kirsten, Vogel, H., Møller, Birger Lindberg & Bak, Søren, 2014, In: P L o S One. 9, 10, 9 p., e108745.

    Research output: Contribution to journalJournal articleResearchpeer-review

  56. Published

    High-throughput cereal metabolomics: current analytical technologies, challenges and perspectives

    Khakimov, Bekzod, Bak, Søren & Engelsen, Søren Balling, 2014, In: Journal of Cereal Science. 59, 3, p. 393-418 26 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  57. Published

    How insects overcome two-component plant chemical defence: plant β-glucosidases as the main target for herbivore adaptation

    Pentzold, S., Zagrobelny, M., Rook, F. & Bak, Søren, 2014, In: Biological Reviews. 89, 3, p. 531-551 21 p.

    Research output: Contribution to journalReviewResearchpeer-review

  58. Published

    Sequestration, tissue distribution and developmental transmission of cyanogenic glucosides in a specialist insect herbivore

    Zagrobelny, M., Olsen, C. E., Pentzold, S., Fürstenberg-Hägg, J., Jørgensen, Kirsten, Bak, Søren, Møller, Birger Lindberg & Motawie, Mohammed Saddik, 2014, In: Insect Biochemistry and Molecular Biology. 44, p. 44-53 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  59. Published

    The multiple strategies of an insect herbivore to overcome plant cyanogenic glucoside defence

    Pentzold, S., Zagrobelny, M., Roelsgaard, P. S., Møller, Birger Lindberg & Bak, Søren, 2014, In: PLOS ONE. 9, 3, 8 p., e91337.

    Research output: Contribution to journalJournal articleResearchpeer-review

  60. Published

    Transcriptional regulation of de novo biosynthesis of cyanogenic glucosides throughout the life-cycle of the burnet moth Zyagena filipendulae (Lepidoptera)

    Fürstenberg-Hägg, J., Zagrobelny, M., Olsen, C. E., Jørgensen, Kirsten, Møller, Birger Lindberg & Bak, Søren, 2014, In: Insect Biochemistry and Molecular Biology. 49, p. 80-89 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  61. 2013
  62. Published

    Biochemical analysis of a multifunctional cytochrome P450 (CYP51) enzyme required for synthesis of antimicrobial triterpenes in plants

    Geisler, K., Hughes, R. K., Sainsbury, F., Lomonossoff, G. P., Rejzek, M., Fairhurst, S., Olsen, C. E., Motawie, Mohammed Saddik, Melton, R. E., Hemmings, A. M., Bak, Søren & Osbourn, A., 2013, In: Proceedings of the National Academy of Sciences of the United States of America. 110, 35, p. E3360-E3367 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  63. Published

    Integrative analysis of metabolomics and transcriptomics data: a unified model framework to identify underlying system pathways

    Brink-Jensen, K., Bak, Søren, Jørgensen, Kirsten & Ekstrøm, Claus Thorn, 2013, In: P L o S One. 8, 9, 8 p., e72116.

    Research output: Contribution to journalJournal articleResearchpeer-review

  64. Published

    Male-to-female transfer of 5-hydroxytryptophan glucoside during mating in Zyagena filipendulae (Lepidoptera)

    Zagrobelny, M., Motawie, Mohammed Saddik, Olsen, C. E., Bak, Søren & Møller, Birger Lindberg, 2013, In: Insect Biochemistry and Molecular Biology. 43, 11, p. 1037-1044 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  65. Published

    Plant P450s as versatile drivers for evolution of species-specific chemical diversity

    Hamberger, B. R. & Bak, Søren, 2013, In: Philosophical Transactions of the Royal Society B: Biological Sciences. 368, 1612, 16 p., 20120426.

    Research output: Contribution to journalJournal articleResearchpeer-review

  66. Published

    Plant defense against insect herbivores

    Fürstenberg-Hägg, J., Zagrobelny, M. & Bak, Søren, 2013, In: International Journal of Molecular Sciences (Online). 14, 5, 56 p.

    Research output: Contribution to journalReviewResearchpeer-review

  67. Published

    The use of trimethylsilyl cyanide derivatization for robust and broad-spectrum high-throughput gas chromatography–mass spectrometry based metabolomics

    Khakimov, Bekzod, Motawie, Mohammed Saddik, Bak, Søren & Engelsen, Søren Balling, 2013, In: Analytical and Bioanalytical Chemistry. 405, 28, p. 9193-9205 13 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  68. Published

    Visualizing metabolite distribution and enzymatic conversion in plant tissues by desorption electrospray ionization mass spectrometry imaging

    Li, B., Baden, C. K., Hansen, N. K. K., Jørgensen, Kirsten, Kannangara, R. M., Bak, Søren, Takos, A. M., Rook, F., Hansen, S. H., Møller, Birger Lindberg, Janfelt, Christian & Bjarnholt, Nanna, 2013, In: Plant Journal. 74, 6, p. 1059-1071 74.

    Research output: Contribution to journalJournal articleResearchpeer-review

  69. 2012
  70. Published

    Biosynthesis of rhodiocyanosides in Lotus japonicus: Rhodiocyanoside A is synthesized from (Z)-2-methylbutanaloxime via 2-methyl-2-butenenitrile

    Saito, S., Motawie, Mohammed Saddik, Olsen, C. E., Møller, Birger Lindberg & Bak, Søren, 2012, In: Phytochemistry. 77, p. 260-267 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  71. Published

    Plant metabolomics: resolution and quantification of elusive peaks in liquid chromatography–mass spectrometry profiles of complex plant extracts using multi-way decomposition methods

    Khakimov, Bekzod, Amigo Rubio, J. M., Bak, Søren & Engelsen, Søren Balling, 2012, In: Journal of Chromatography A. 1266, p. 84-94 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  72. Published

    UDP-glycosyltransferases from the UGT73C subfamily in Barbarea vulgaris catalyse Sapogenin 3-O-glucosylation in Saponin-mediated Insect resistance

    Augustin, J. M., Drok, S., Shinoda, T., Sanmiya, K., Nielsen, J. K., Khakimov, Bekzod, Olsen, C. E., Hansen, E. H., Poulsen, V. K., Ekstrøm, Claus Thorn, Hauser, T. P. & Bak, Søren, 2012, In: Plant Physiology. 160, 4, p. 1881-1895 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  73. 2011
  74. Published

    Barbarea vulgaris linkage map and quantitative trait loci for saponins, glucosinolates, hairiness and resistance to the herbivore Phyllotreta nemorum

    Poulsen, V. K., Nielsen, J. K., Augustin, J. M., Torp, A. M., Bak, Søren & Andersen, S. B., 2011, In: Phytochemistry. 72, 2-3, p. 188-198 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  75. Published

    Biosynthesis of the cyanogenic glucosides linamarin and lotaustralin in cassava: isolation, biochemical, characterization, and expression pattern of CYP71E7, the oxime-metabolizing cytochrome P450 enzyme

    Jørgensen, Kirsten, Morant, A. V., Morant, M., Jensen, N. B., Olsen, C. E., Kannangara, R. M., Motawie, Mohammed Saddik, Møller, Birger Lindberg & Bak, Søren, 2011, In: Plant Physiology. 155, 1, p. 282-292 11 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  76. Published

    Convergent evolution in biosynthesis of cyanogenic defence compounds in plants and insects

    Jensen, N. B., Zagrobelny, M., Hjernø, K., Olsen, C. E., Hougton-Larsen, J., Borch-Jensen, J., Møller, Birger Lindberg & Bak, Søren, 2011, In: Nature Communications. 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  77. Published

    Cytochromes P450

    Bak, Søren, Beisson, F., Bishop, G., Hamberger, B. R., Höfer, R., Paquette, S. & Werck-Reichhart, D., 2011, The arabidopsis book. American Society of Plant Biologists, 56 p.

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  78. Published

    Molecular activities, biosynthesis and evolution of triterpenoid saponins

    Augustin, J. M., Poulsen, V. K., Andersen, S. B. & Bak, Søren, 2011, In: Phytochemistry. 72, 6, p. 435-457 23 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  79. 2010
  80. Published

    454 pyrosequencing based transcriptome analysis of Zygaena filipendulae with focus on genes involved in biosynthesis of cyanogenic glucosides

    Zagrobelny, M., Scheibye-Alsing, K., Jensen, N. B., Møller, Birger Lindberg, Gorodkin, Jan & Bak, Søren, 2010.

    Research output: Contribution to conferencePosterResearch

  81. Published

    454 pyrosequencing based transcriptome analysis of Zygaena filipendulae with focus on genes involved in biosynthesis of cyanogenic glucosides

    Zagrobelny, M., Scheibye-Alsing, K., Jensen, N. B., Møller, Birger Lindberg, Gorodkin, Jan & Bak, Søren, 2010.

    Research output: Contribution to conferencePosterResearch

  82. Published

    The role of saponins in the tripartite interaction between Barbarea vulgaris (Brassicaceae), flea beetles and white rust.

    van Mölken, M. A. R., Hauser, T. P., Andersen, S. B., Augustin, J. M., Bak, Søren, Poulsen, V. K., Munk, Lisa & Nielsen, J. K., 2010.

    Research output: Contribution to conferencePosterResearch

  83. Published

    Interactions between Barbarea vulgaris, flea beetles and white rust

    Hauser, T. P., Andersen, S. B., Augustin, J. M., Bak, Søren, Poulsen, V. K. & Munk, Lisa, 2010.

    Research output: Contribution to conferencePosterResearch

  84. Published

    Metabolomic, transcriptional, hormonal, and signaling cross-talk in Superroot2

    Morant, M. D., Ekstrøm, Claus Thorn, Ulvskov, Peter, Kristensen, C., Rudemo, M. E., Olsen, C. E., Hansen, J., Jørgensen, Kirsten, Jørgensen, B., Møller, Birger Lindberg & Bak, Søren, 2010, In: Molecular Plant. 3, 1, p. 192-211 20 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  85. Published

    Planters naturlige forsvar mod forskellige samtidige skadevoldere

    Hauser, T. P., Nielsen, J. K., Munk, Lisa, Poulsen, V. K., Bak, Søren, van Mölken, T. & Andersen, S. B., 2010, Plantekongres 2010: sammendrag af indlæg: 12-14 januar i Herning Kongrescenter. Dansk Landbrugsrådgivning, p. 402-403 2 p.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearch

  86. 2009
  87. Published

    454 pyrosequencing based transcriptome analysis of Zygaena filipendulae with focus on genes involved in biosynthesis of cyanogenic glucosides

    Zagrobelny, M., Scheibye-Alsing, K., Jensen, N. B., Møller, Birger Lindberg, Gorodkin, Jan & Bak, Søren, 2009, In: BMC Genomics. 10, 574, 15 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  88. Published

    Lotus japonicus as a model system to study evolution and function of cyanogenic glucosides in plant-insect interactions

    Bak, Søren, Saito, S., Takos, A. M., Zagrobelny, M., Bjarnholt, Nanna, Jensen, N. B., Rook, F., Martin, C. R. & Møller, Birger Lindberg, 2009.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  89. Published

    A web-based resource for the Arabidopsis P450, cytochromes b5, NADPH-cytochrome P450 reductases, and family 1 glycosyltransferases

    Paquette, S. M., Jensen, K. & Bak, Søren, 2009, In: Phytochemistry. 70, 17-18, p. 1940-1947 8 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  90. Published

    Ecogenomic and ecometabolomic approaches to unraveling natural plant resistance to insects

    Poulsen, V. K., Augustin, J. M., Andersen, S. B., Ekstrøm, Claus Thorn, Nielsen, J. K., Olsen, C. E. & Bak, Søren, 2009. 1 p.

    Research output: Contribution to conferencePaperResearch

  91. Published

    Ecometabolomic Approach for Identification of Defensive Compounds in Plants towards Herbivorous Insects

    Poulsen, V. K., Andersen, S. B., Ekstrøm, Claus Thorn, Nielsen, J. K., Olsen, C. E. & Bak, Søren, 2009.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  92. Published

    Effect of glucuronosylation on anthocyanin color stability

    Osmani, S. A., Hansen, E. H., Malien-Aubert, C., Olsen, C. E., Bak, Søren & Møller, Birger Lindberg, 2009, In: Journal of Agricultural and Food Chemistry. 57, 8, p. 3149-3155 7 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  93. Published

    Genes involved in metabolism of cyanogenic glucosides in Zygaena filipendulae determined by 454 pyrosequencing

    Zagrobelny, M., Scheibye-Alsing, K., Jensen, N. B., Møller, Birger Lindberg, Gorodkin, Jan & Bak, Søren, 2009.

    Research output: Contribution to conferencePosterResearch

  94. Published

    Identification of defense compounds in Barbarea vulgaris against the herbivore Phyllotreta nemorum by an ecometabolomic approach

    Poulsen, V. K., Ekstrøm, Claus Thorn, Andersen, S. B., Nielsen, J. K., Olsen, C. E. & Bak, Søren, 2009, In: Plant Physiology. 151, 4, p. 1977-1990 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  95. Published

    Metabolon formation in natural product synthesis studied by anchoring the biosynthetic pathway for cyanogenic glucoside synthesis in NanoDiscs and 3D modeling of the interacting partners

    Osmani, S. A., Hamann, T., Grimme, S., Bak, Søren, Sligar, S. G. & Møller, Birger Lindberg, 2009.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  96. Published

    Microarray analysis of phenylpropanoid metabolism in the model legume Lotus japonicus

    Shelton, D. A., Bailey, P., Mikkelsen, L., Takos, A. M., Bak, Søren, Wang, T., Rook, F. & Martin, C. R., 2009.

    Research output: Contribution to conferencePosterResearch

  97. Published

    Microarray analysis of phenylpropanoid metabolism in the model legume Lotus japonicus

    Shelton, D. A., Bailey, P., Takos, A. M., Bak, Søren, Wang, T., Rook, F. & Martin, C. R., 2009.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  98. Published

    Microarray analysis of phenylpropanoid metabolism in the model legume Lotus japonicus

    Shelton, D. A., Bailey, P., Mikkelsen, L., Takos, A. M., Bak, Søren, Wang, T., Rook, F. & Martin, C. R., 2009. 1 p.

    Research output: Contribution to conferencePosterResearch

  99. Published

    Microarray analysis of phenylpropanoid metabolism in the model legume Lotus japonicus

    Shelton, D. A., Bailey, P., Takos, A. M., Bak, Søren, Wang, T., Rook, F. & Martin, C. R., 2009.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  100. Published

    Natural variation in hydroxynitrile glucosides in the model legume Lotus japonicus

    Mikkelsen, L., Bjarnholt, Nanna, Olsen, C. E., Takos, A. M., Wang, T., Møller, Birger Lindberg, Bak, Søren, Martin, C. R. & Rook, F., 2009.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  101. Published

    Recruitment of cytocromes P450 for evolution of new natural products in Lotus japonicus

    Saito, S., Engelbrecht, J., Olsen, C. E., Møller, Birger Lindberg & Bak, Søren, 2009.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  102. Published

    Regulation of isoflavonoid biosynthesis in the model legume Lotus japonicus

    Shelton, D. A., Bailey, P., Olsen, C. E., Mikkelsen, L., Takos, A. M., Wang, T., Bak, Søren, Rook, F. & Martin, C. R., 2009.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  103. Published

    Substrate specificity of plant UDP-dependent glycosyltransferases predicted from crystal structures and homology modeling

    Osmani, S. A., Bak, Søren & Møller, Birger Lindberg, 2009, In: Phytochemistry. 70, 3, p. 325-347 23 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  104. Published

    Unraveling the biosynthetic pathway of triterpenoid saponins in Barbarea vulgaris

    Augustin, J. M., Poulsen, V. K., Andersen, S. B., Nielsen, J. K. & Bak, Søren, 2009. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  105. Published

    Unraveling the biosynthetic pathway of triterpenoid saponins in Barbarea vulgaris

    Augustin, J. M., Poulsen, V. K., Andersen, S. B., Nielsen, J. K. & Bak, Søren, 2009. 1 p.

    Research output: Contribution to conferencePosterResearch

  106. 2008
  107. Published

    CYP703 catalyzes in-chain hydroxylation of lauric acid to provide building blocks for sporopollenin synthesis

    Morant, M., Jørgensen, Kirsten, Schaller, H., Pinot, F., Olsen, C. E., Werck-Reichhart, D., Møller, Birger Lindberg & Bak, Søren, 2008.

    Research output: Contribution to conferencePosterResearch

  108. Published

    Catalytic key amino acids and UDP-sugar donor specificity of a plant glucuronosyltransferase, UGT94B1: molecular modeling substantiated by site-specific mutagenesis and biochemical analyses

    Osmani, S. A., Bak, Søren, Imberty, A., Olsen, C. E. & Møller, Birger Lindberg, 2008, In: Plant Physiology. 148, p. 1295-1308 14 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  109. Published

    Cyanogenesis in plants and arthropods

    Zagrobelny, M., Bak, Søren & Møller, Birger Lindberg, 2008, In: Phytochemistry. 69, 7, p. 1457-1468 12 p.

    Research output: Contribution to journalReviewResearchpeer-review

  110. Published

    Cyanogenic glucosides as determinants of feeding preference in Zygaena filipendulae (Linnaeus, 1758) (Lepidoptera, Zygaenidae)

    Zagrobelny, M., Bak, Søren & Møller, Birger Lindberg, 2008, Les chaires du musée des confluences: vol. 2: l'expérimentation. Drouet, E. (ed.). Musée des Confluences, p. 113-122 10 p.

    Research output: Chapter in Book/Report/Conference proceedingArticle in proceedingsResearchpeer-review

  111. Published

    Cyanogenic glucosides in primary and secondary metabolism

    Sánchez-Pérez, R., Zagrobelny, M., Jørgensen, Kirsten, Bak, Søren & Møller, Birger Lindberg, 2008.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  112. Published

    Diversification of an ancient theme: hydroxynitrile glucosides

    Bjarnholt, Nanna, Rook, F., Motawie, Mohammed Saddik, Cornett, Claus, Jørgensen, C., Olsen, C. E., Jaroszewski, J. W., Bak, Søren & Møller, Birger Lindberg, 2008, In: Phytochemistry. 69, 7, p. 1507-1516 10 p.

    Research output: Contribution to journalJournal articleResearchpeer-review

  113. Published

    Diversification of an ancient theme: hydroxynitrile glucosides

    Bjarnholt, Nanna, Rook, F., Motawie, Mohammed Saddik, Cornett, Claus, Olsen, C. E., Jaroszewski, J. W., Bak, Søren & Møller, Birger Lindberg, 2008.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  114. Published

    Erratum: Cyanogenic glycosides: A case study for evolution and application of cytochromes P450 (Phytochemistry Reviews (2006) 5, (309-329) DOI: 10.1007/s11101-006-9033-1)

    Bak, Søren, Paquette, S. M., Morant, M., Morant, A. V., Saito, S., Bjarnholt, Nanna, Zagrobelny, M., Jørgensen, K., Osmani, S., Hamann, T., Simonsen, H. T., Pérez, R. S., Van Heeswijck, T. B., Jørgensen, Bodil & Møller, Birger Lindberg, 2008, In: Phytochemistry Reviews. 7, 1, p. 209 1 p.

    Research output: Contribution to journalComment/debateResearchpeer-review

  115. Published

    Is evolutionary speed related to function in the Arabidopsis cytochrome P450 multigene family?

    Engelbrecht, J. & Bak, Søren, 2008.

    Research output: Contribution to conferencePosterResearch

  116. Published

    Is evolutionary speed related to function in the Arabidopsis cytochrome P450 multigene family?

    Engelbrecht, J. & Bak, Søren, 2008.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  117. Published

    Isoflavonoid Biosynthesis in the Model Legume Lotus japonicus

    Shelton, D., Bailey, P., Olsen, C. E., Mikkelsen, L., Takos, A., Bak, Søren, Rook, F., Wang, T. & Martin, C., 2008.

    Research output: Contribution to conferencePosterResearch

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