Fernando Geu-Flores

Fernando Geu-Flores

Associate Professor


  1. 2023
  2. Published

    An improved Nicotiana benthamiana bioproduction chassis provides novel insights into nicotine biosynthesis

    Vollheyde, K., Dudley, Q. M., Yang, T., Oz, M. T., Mancinotti, Davide, Fedi, M. O., Heavens, D., Linsmith, G., Chhetry, M., Smedley, M. A., Harwood, W. A., Swarbreck, D., Geu-Flores, Fernando & Patron, N. J., 2023, In: New Phytologist. 240, 1, p. 302-317 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  3. Published
  4. Published

    The causal mutation leading to sweetness in modern white lupin cultivars

    Mancinotti, Davide, Czepiel, K., Taylor, J. L., Galehshahi, H. G., Møller, L. A., Jensen, M. K., Motawie, Mohammed Saddik, Hufnagel, B., Soriano, A., Yeheyis, L., Kjaerulff, Louise, Péret, B., Stærk, Dan, Wendt, T., Nelson, M. N., Kroc, M. & Geu-Flores, Fernando, 2023, In: Science Advances. 9, 31, 10 p., eadg8866.

    Research output: Contribution to journalJournal articlepeer-review

  5. 2022
  6. Published
  7. Published

    Biosynthesis of quinolizidine alkaloids in lupins: mechanistic considerations and prospects for pathway elucidation

    Mancinotti, Davide, Frick, Karen Michiko & Geu-Flores, Fernando, 2022, In: Natural Product Reports. 39, 7, p. 1423-1437 15 p.

    Research output: Contribution to journalReviewpeer-review

  8. Published

    Prospects to improve the nutritional quality of crops. Food and Energy Security

    Scharff, L., Saltenis, V. L. R., Jensen, P. E., Baekelandt, A., Burgess, A. J., Burow, M., Ceriotti, A., Cohan, J-P., Geu-Flores, F., Halkier, B. A., Haslam, R. P., Inzé, D., Lankhorst, R. K., Murchie, E., Napier, J. A., Nacry, P., Parry, M. A. J., Santino, A., Scarano, A., Sparvoli, F. & 2 others, Wilhelm, R. & Pribil, Mathias, 2022, In: Food and Energy Security. 11, 1, 14 p., e327.

    Research output: Contribution to journalJournal articlepeer-review

  9. 2021
  10. Published

    Bioengineering potato plants to produce benzylglucosinolate for improved broad-spectrum pest and disease resistance

    González-Romero, M. E., Rivera, C., Cancino, K., Geu-Flores, Fernando, Cosio, E. G., Ghislain, M. & Halkier, Barbara Ann, 2021, In: Transgenic Research. 30, p. 649-660 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  11. Published

    Development and application of a virus-induced gene silencing protocol for the study of gene function in narrow-leafed lupin

    Mancinotti, Davide, Rodriguez, M. C., Frick, Karen Michiko, Dueholm, B., Jepsen, D. G., Agerbirk, Niels & Geu-Flores, Fernando, 2021, In: Plant Methods. 17, 1, 13 p., 131.

    Research output: Contribution to journalJournal articlepeer-review

  12. Published

    VC1 catalyses a key step in the biosynthesis of vicine in faba bean

    Björnsdotter, E., Nadzieja, M., Chang, W., Escobar-Herrera, L., Mancinotti, Davide, Angra, D., Xia, Xinxing, Tacke, R., Khazaei, H., Crocoll, C., Vandenberg, A., Link, W., Stoddard, F. L., O'Sullivan, D. M., Stougaard, J., Schulman, A. H., Andersen, S. U. & Geu-Flores, Fernando, 2021, In: Nature Plants. 7, p. 923–931

    Research output: Contribution to journalJournal articlepeer-review

  13. 2020
  14. Published

    High-quality genome sequence of white lupin provides insight into soil exploration and seed quality

    Hufnagel, B., Marques, A., Soriano, A., Marquès, L., Divol, F., Doumas, P., Sallet, E., Mancinotti, D., Carrere, S., Marande, W., Arribat, S., Keller, J., Huneau, C., Blein, T., Aimé, D., Laguerre, M., Taylor, J., Schubert, V., Nelson, M., Geu-Flores, F. & 8 others, Crespi, M., Gallardo, K., Delaux, P., Salse, J., Bergès, H., Guyot, R., Gouzy, J. & Péret, B., 2020, In: Nature Communications. 11, 1, 12 p., 492.

    Research output: Contribution to journalJournal articlepeer-review

  15. 2019
  16. Published

    Quinolizidine alkaloids are transported to seeds of bitter narrow-leafed lupin

    Otterbach, S. L., Yang, T., Kato, L., Janfelt, Christian & Geu-Flores, Fernando, 15 Oct 2019, In: Journal of Experimental Botany. 70, 20, p. 5799-5808

    Research output: Contribution to journalJournal articlepeer-review

  17. Published

    Eliminating vicine and convicine, the main anti-nutritional factors restricting faba bean usage

    Khazaei, H., Purves, R. W., Hughes, J., Link, W., O'Sullivan, D. M., Schulman, A. H., Björnsdotter, E., Geu-Flores, Fernando, Nadzieja, M., Andersen, S. U., Stougaard, J., Vandenberg, A. & Stoddard, F. L., Sep 2019, In: Trends in Food Science and Technology. 91, p. 549-556

    Research output: Contribution to journalReviewpeer-review

  18. 2017
  19. Published

    An NPF transporter exports a central monoterpene indole alkaloid intermediate from the vacuole

    Payne, R., Xu, Deyang, Foureau, E., Ines Soares Teto Carqueijeiro, M., Oudin, A., Dugé de Bernonville, T., Novák, V., Burow, Meike, Olsen, C. E., Jones, D. M., C. Tatsis, E., Pendleton, A., Halkier, Barbara Ann, Geu-Flores, Fernando, Courdavault, V., Nour-Eldin, Hussam Hassan & O'Connor, S. E., 2017, In: Nature Plants. 3, 9 p., 16208.

    Research output: Contribution to journalJournal articlepeer-review

  20. Published

    Transcript profiling of a bitter variety of narrow-leafed lupin to discover alkaloid biosynthetic genes

    Yang, T., Nagy, I., Mancinotti, Davide, Otterbach, S. L., Andersen, T. B., Motawie, Mohammed Saddik, Asp, T. & Geu-Flores, Fernando, 2017, In: Journal of Experimental Botany. 68, 20, p. 5527-5537 11 p.

    Research output: Contribution to journalJournal articlepeer-review

  21. 2016
  22. Published

    Glucosinolate diversity within a phylogenetic framework of the tribe Cardamineae (Brassicaceae) unraveled with HPLC-MS/MS and NMR-based analytical distinction of 70 desulfoglucosinolates

    Olsen, C. E., Huang, X., Hansen, Cecilie Ida Cetti, Cipollini, D., Ørgaard, Marian, Matthes, A., Geu-Flores, Fernando, Koch, M. A. & Agerbirk, Niels, 2016, In: Phytochemistry. 132, p. 33-56 24 p.

    Research output: Contribution to journalJournal articlepeer-review

  23. Published

    Identification and characterization of the iridoid synthase involved in oleuropein biosynthesis in olive (Olea europaea) fruits

    Alagna, F., Geu-Flores, Fernando, Kries, H., Panara, F., Baldoni, L., O'Connor, S. E. & Osbourn, A., 2016, In: Journal of Biological Chemistry. 291, 11, p. 5542-5554 13 p.

    Research output: Contribution to journalJournal articlepeer-review

  24. Published

    Structural determinants of reductive terpene cyclization in iridoid biosynthesis

    Kries, H., Caputi, L., Stevenson, C. E. M., Kamileen, M. O., Sherden, N. H., Geu-Flores, Fernando, Lawson, D. M. & O'Connor, S. E., 2016, In: Nature Chemical Biology. 12, 1, p. 6-8 3 p.

    Research output: Contribution to journalJournal articlepeer-review

  25. Published

    Transcriptome sequencing in narrow-leafed lupin (Lupinus angustifolius): combining short- and long-read sequencing platforms

    Yang, T., Nagy, I., Asp, T. & Geu-Flores, Fernando, 2016, In: Planta Medica. 82, S 01, 1 p.

    Research output: Contribution to journalConference abstract in journalpeer-review

  26. 2015
  27. Published

    Discovery of a P450-catalyzed step in vindoline biosynthesis: a link between the aspidosperma and eburnamine alkaloids

    Kellner, F., Geu-Flores, Fernando, Sherden, N. H., Brown, S., Foureau, E., Courdavault, V. & O'Connor, S. E., 2015, In: Chemical Communications. 51, 36, p. 7626-7628 3 p.

    Research output: Contribution to journalJournal articlepeer-review

  28. 2014
  29. Conversion of substrate analogs suggests a Michael cyclization in iridoid biosynthesis

    Lindner, S., Geu-Flores, Fernando, Bräse, S., Sherden, N. H. & O'Connor, S. E., 2014, In: Chemistry & Biology. 21, 11, p. 1452-1456 5 p.

    Research output: Contribution to journalJournal articlepeer-review

  30. 2013
  31. Published

    De novo genetic engineering of the camalexin biosynthetic pathway

    Møldrup, M. E., Salomonsen, B., Geu-Flores, Fernando, Olsen, C. E. & Halkier, Barbara Ann, 2013, In: Journal of Biotechnology. 167, 3, p. 296-301 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  32. A pair of tabersonine 16-hydroxylases initiates the synthesis of vindoline in an organ-dependent manner in Catharanthus roseus

    Besseau, S., Kellner, F., Lanoue, A., Thamm, A. M. K., Salim, V., Schneider, B., Geu Flores, F., Höfer, R., Guirimand, G., Guihur, A., Oudin, A., Glevarec, G., Foureau, E., Papon, N., Clastre, M., Giglioli-Guivarc'h, N., St-Pierre, B., Werck-Reichhart, D., Burlat, V., De Luca, V. & 2 others, O'Connor, S. E. & Courdavault, V., 2013, In: Plant Physiology. 163, 4, p. 1792-803 12 p.

    Research output: Contribution to journalJournal articlepeer-review

  33. 2012
  34. An alternative route to cyclic terpenes by reductive cyclization in iridoid biosynthesis

    Geu-Flores, Fernando, Sherden, N. H., Courdavault, V., Burlat, V., Glenn, W. S., Wu, C., Nims, E., Cui, Y. & O'Connor, S. E., 2012, In: Nature. 492, 7427, p. 138-42 5 p.

    Research output: Contribution to journalLetterpeer-review

  35. Published

    Engineering of benzylglucosinolate in tobacco provides proof-of-concept for dead-end trap crops genetically modified to attract Plutella xylostella (diamondback moth)

    Møldrup, M. E., Geu-Flores, Fernando, de Vos, M., Olsen, C. E., Sun, J., Jander, G. & Halkier, Barbara Ann, 2012, In: Plant Biotechnology Journal. 10, 4, p. 435-442 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  36. 2011
  37. Published

    Cytosolic γ-glutamyl peptidases process glutathione conjugates in the biosynthesis of glucosinolates and camalexin in Arabidopsis

    Geu-Flores, Fernando, Møldrup, M. E., Böttcher, C., Olsen, C. E., Scheel, D. & Halkier, Barbara Ann, 2011, In: Plant Cell. 23, 6, p. 2456-2469 14 p.

    Research output: Contribution to journalJournal articlepeer-review

  38. Published

    Modulation of sulfur metabolism enables efficient glucosinolate engineering

    Møldrup, M. E., Geu-Flores, Fernando, Olsen, C. E. & Halkier, Barbara Ann, 2011, In: B M C Biotechnology. 11, 12, 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  39. 2010
  40. Published

    Biosynthesis of glucosinolates - gene discovery and beyond

    Sønderby, I. E., Geu-Flores, Fernando & Halkier, Barbara Ann, 2010, In: Trends in Plant Science. 15, 5, p. 283-290 8 p.

    Research output: Contribution to journalJournal articlepeer-review

  41. Published

    USER cloning and USER fusion: the ideal cloning techniques for small and big laboratories

    Nour-Eldin, Hussam Hassan, Geu-Flores, Fernando & Halkier, Barbara Ann, 2010, Plant secondary metabolism engineering: methods and applications. Fett-Neto, A. G. (ed.). Springer Science+Business Media, Vol. 643. p. 185-200 16 p. (Methods in Molecular Biology, Vol. 643).

    Research output: Chapter in Book/Report/Conference proceedingBook chapterResearchpeer-review

  42. 2009
  43. Published

    A toolkit for engineering multi-enzyme pathways into higher plants

    Geu-Flores, Fernando, Nielsen, M. T., Motawie, Mohammed Saddik, Olsen, C. E. & Halkier, Barbara Ann, 2009.

    Research output: Contribution to conferencePosterResearch

  44. Published

    A toolkit for engineering multi-enzyme pathways into higher plants

    Geu-Flores, Fernando, Nielsen, M. T., Møldrup, M. E., Olsen, C. E., Motawie, Mohammed Saddik & Halkier, Barbara Ann, 2009. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  45. Published

    Engineering benzylglucosinolate into tobacco

    Mikkelsen, M. D., Geu-Flores, Fernando, Nielsen, M. T., Nafisi, M., Møldrup, M. E., Olsen, C. E., Motawie, Mohammed Saddik & Halkier, Barbara Ann, 2009. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  46. Published

    Engineering of benzyl glucosinolate identifies a critical γ-glutamyl peptidase

    Geu-Flores, Fernando, Nielsen, M. T., Nafisi, M., Møldrup, M. E., Olsen, C. E., Motawie, Mohammed Saddik & Halkier, Barbara Ann, 2009. 1 p.

    Research output: Contribution to conferencePosterResearch

  47. Published

    Glucosinolate engineering identifies a missing biosynthetic enzyme

    Geu-Flores, Fernando, Nielsen, M. T., Nafisi, M., Møldrup, M. E., Motawie, Mohammed Saddik, Olsen, C. E. & Halkier, Barbara Ann, 2009. 1 p.

    Research output: Contribution to conferencePosterResearch

  48. Published

    Glucosinolate engineering identifies a ¿-glutamyl peptidase

    Geu-Flores, Fernando, Nielsen, M. T., Nafisi, M., Møldrup, M. E., Olsen, C. E., Motawie, Mohammed Saddik & Halkier, Barbara Ann, 2009, In: Nature Chemical Biology. 5, p. 575-577 3 p.

    Research output: Contribution to journalJournal articlepeer-review

  49. Published

    Towards engineering glucosinolates into non-cruciferous plants

    Geu-Flores, Fernando, Olsen, C. E. & Halkier, Barbara Ann, 2009, In: Planta. 229, 2, p. 261-270 10 p.

    Research output: Contribution to journalJournal articlepeer-review

  50. 2008
  51. Published

    Engineering glucosinolates into non-crucifers

    Geu-Flores, Fernando, 2008, Department of Plant Biology, University of Copenhagen.

    Research output: Book/ReportPh.D. thesis

  52. 2007
  53. Published

    Engineering the glucosinolate pathway into potato

    Geu-Flores, Fernando, Halkier, Barbara Ann & Ghislan, M., 2007. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  54. Published

    USER fusion: a rapid and efficient method for simultaneous fusion and cloning of multiple PCR products

    Geu-Flores, Fernando, Nour-Eldin, Hussam Hassan, Nielsen, M. T. & Halkier, Barbara Ann, 2007, In: Nucleic Acids Research. 35, 7, 6 p.

    Research output: Contribution to journalJournal articlepeer-review

  55. Published

    Uracil-excision based cloning and DNA-fusion technology - an ideal platform for both high-troughput and single-gene plant molecular biology

    Nørholm, M. H. H., Nour-Eldin, Hussam Hassan, Hansen, B. G., Jensen, J. K., Geu-Flores, Fernando, Nielsen, M. T. & Halkier, Barbara Ann, 2007. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  56. Published

    Uracil-excision based cloning and DNA-fusion technology – an ideal platform for both high-throughput and single-gene plant molecular biology

    Nørholm, M. H. H., Nour-Eldin, Hussam Hassan, Hansen, B. G., Jensen, J. K., Geu-Flores, Fernando, Nielsen, M. T. & Halkier, Barbara Ann, 2007. 1 p.

    Research output: Contribution to conferencePosterResearch

  57. Published

    Uracil-excision based cloning and DNA-fusion technology – an ideal platform for both high-throughput and single-gene plant molecular biology

    Geu-Flores, Fernando, Nørholm, M. H. H., Nour-Eldin, Hussam Hassan, Hansen, B. G., Jensen, J. K., Nielsen, M. T. & Halkier, Barbara Ann, 2007. 1 p.

    Research output: Contribution to conferencePosterResearch

  58. 2006
  59. Published

    Cytochromes P450 in the biosynthesis of glucosinolates and indole alkaloids

    Nafisi, M., Sønderby, I. E., Hansen, B. G., Geu-Flores, Fernando, Nour-Eldin, Hussam Hassan, Nørholm, M. H. H., Jensen, N. B., Li, J. & Halkier, Barbara Ann, 2006, In: Phytochemistry Reviews. 5, 2-3, p. 331-346 16 p.

    Research output: Contribution to journalJournal articlepeer-review

  60. Published

    Engineering the glucosinolate pathway into potato

    Geu-Flores, Fernando, Halkier, Barbara Ann, Ghislain, M. & Cosio, E., 2006. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  61. Published

    Engineering the glucosinolate pathway into yeast

    Geu-Flores, Fernando, Nielsen, M. T. & Halkier, Barbara Ann, 2006. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  62. Published

    Engineering the glucosinolate pathway into yeast

    Geu-Flores, Fernando, Nielsen, M. T. & Halkier, Barbara Ann, 2006. 1 p.

    Research output: Contribution to conferencePosterResearch

  63. Published

    Engineering the glucosinolate pathway into yeast

    Geu-Flores, Fernando, Nielsen, M. T. & Halkier, Barbara Ann, 2006. 1 p.

    Research output: Contribution to conferencePosterResearch

  64. Published

    Heterologous expression of the glucosinolate pathway

    Geu-Flores, Fernando, Nielsen, M. T., Ghislain, M., Cosio, E. & Halkier, Barbara Ann, 2006. 1 p.

    Research output: Contribution to conferenceConference abstract for conferenceResearch

  65. 2005
  66. Published

    Engineering the glucosinolate pathway into potato

    Geu-Flores, Fernando, Halkier, Barbara Ann, Ghislain, M. & Cosio, E., 2005. 1 p.

    Research output: Contribution to conferencePosterResearch

ID: 37992063