Whole genome analysis of a schistosomiasis-transmitting freshwater snail
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- Whole genome analysis of a schistosomiasis-transmitting freshwater snail
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Biomphalaria snails are instrumental in transmission of the human blood fluke Schistosoma mansoni. With the World Health Organization's goal to eliminate schistosomiasis as a global health problem by 2025, there is now renewed emphasis on snail control. Here, we characterize the genome of Biomphalaria glabrata, a lophotrochozoan protostome, and provide timely and important information on snail biology. We describe aspects of phero-perception, stress responses, immune function and regulation of gene expression that support the persistence of B. glabrata in the field and may define this species as a suitable snail host for S. mansoni. We identify several potential targets for developing novel control measures aimed at reducing snail-mediated transmission of schistosomiasis.
Originalsprog | Engelsk |
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Artikelnummer | 15451 |
Tidsskrift | Nature Communications |
Vol/bind | 8 |
Antal sider | 11 |
ISSN | 2041-1723 |
DOI | |
Status | Udgivet - 2017 |
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